FR2260580A1 - 5-Phenyl benzodiazepines prepn - from 2-(azidoacetylamino) benzophenones by conversion to phosphorus imine then cyclising - Google Patents
5-Phenyl benzodiazepines prepn - from 2-(azidoacetylamino) benzophenones by conversion to phosphorus imine then cyclisingInfo
- Publication number
- FR2260580A1 FR2260580A1 FR7503963A FR7503963A FR2260580A1 FR 2260580 A1 FR2260580 A1 FR 2260580A1 FR 7503963 A FR7503963 A FR 7503963A FR 7503963 A FR7503963 A FR 7503963A FR 2260580 A1 FR2260580 A1 FR 2260580A1
- Authority
- FR
- France
- Prior art keywords
- benzophenones
- benzodiazepines
- hydrocarbyl
- azidoacetylamino
- cyclising
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 phosphorus imine Chemical class 0.000 title abstract 2
- MMBZNMSKMXJMPU-UHFFFAOYSA-N 2-azido-N-(2-benzoylphenyl)acetamide Chemical class N(=[N+]=[N-])CC(=O)NC1=C(C(=O)C2=CC=CC=C2)C=CC=C1 MMBZNMSKMXJMPU-UHFFFAOYSA-N 0.000 title 1
- PWESPFNZUJSUOH-UHFFFAOYSA-N 5-phenyl-1h-1,2-benzodiazepine Chemical class C12=CC=CC=C2NN=CC=C1C1=CC=CC=C1 PWESPFNZUJSUOH-UHFFFAOYSA-N 0.000 title 1
- 238000006243 chemical reaction Methods 0.000 title 1
- 229910052698 phosphorus Inorganic materials 0.000 title 1
- 239000011574 phosphorus Substances 0.000 title 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000008366 benzophenones Chemical class 0.000 abstract 2
- 150000002466 imines Chemical class 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000005236 alkanoylamino group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229940049706 benzodiazepine Drugs 0.000 abstract 1
- 150000001557 benzodiazepines Chemical class 0.000 abstract 1
- 239000012965 benzophenone Substances 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/22—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NLAANVRAGE7401801,A NL162379C (nl) | 1974-02-08 | 1974-02-08 | Werkwijze ter bereiding van benzodiazepinederivaten. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2260580A1 true FR2260580A1 (en) | 1975-09-05 |
| FR2260580B3 FR2260580B3 (enrdf_load_html_response) | 1977-10-21 |
Family
ID=19820720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7503963A Granted FR2260580A1 (en) | 1974-02-08 | 1975-02-07 | 5-Phenyl benzodiazepines prepn - from 2-(azidoacetylamino) benzophenones by conversion to phosphorus imine then cyclising |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS50112389A (enrdf_load_html_response) |
| BE (1) | BE825300A (enrdf_load_html_response) |
| DE (1) | DE2504937A1 (enrdf_load_html_response) |
| DK (1) | DK39775A (enrdf_load_html_response) |
| FR (1) | FR2260580A1 (enrdf_load_html_response) |
| IL (1) | IL46575A0 (enrdf_load_html_response) |
| IN (1) | IN138664B (enrdf_load_html_response) |
| NL (1) | NL162379C (enrdf_load_html_response) |
| NO (1) | NO750400L (enrdf_load_html_response) |
| ZA (1) | ZA75713B (enrdf_load_html_response) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3021107A1 (de) * | 1980-06-04 | 1981-12-17 | Hoechst Ag, 6000 Frankfurt | Carbamoyloxyamino-1,4-benzodiazepine, verfahren zu irer herstellung und diese enthaltende arzneimittel |
| CN115304554B (zh) * | 2022-09-19 | 2023-07-07 | 公安部物证鉴定中心 | 一种2’-氯地西泮-d3的制备方法 |
-
1974
- 1974-02-08 NL NLAANVRAGE7401801,A patent/NL162379C/xx not_active IP Right Cessation
-
1975
- 1975-02-04 ZA ZA00750713A patent/ZA75713B/xx unknown
- 1975-02-05 IL IL46575A patent/IL46575A0/xx unknown
- 1975-02-06 DK DK39775*#A patent/DK39775A/da unknown
- 1975-02-06 DE DE19752504937 patent/DE2504937A1/de not_active Withdrawn
- 1975-02-07 BE BE153162A patent/BE825300A/xx unknown
- 1975-02-07 FR FR7503963A patent/FR2260580A1/fr active Granted
- 1975-02-07 IN IN225/CAL/75A patent/IN138664B/en unknown
- 1975-02-07 NO NO750400A patent/NO750400L/no unknown
- 1975-02-08 JP JP50015912A patent/JPS50112389A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NL162379B (nl) | 1979-12-17 |
| DK39775A (enrdf_load_html_response) | 1975-09-29 |
| FR2260580B3 (enrdf_load_html_response) | 1977-10-21 |
| NL7401801A (nl) | 1975-08-12 |
| NL162379C (nl) | 1984-07-16 |
| JPS50112389A (enrdf_load_html_response) | 1975-09-03 |
| IN138664B (enrdf_load_html_response) | 1976-03-13 |
| IL46575A0 (en) | 1975-04-25 |
| DE2504937A1 (de) | 1975-08-14 |
| BE825300A (nl) | 1975-08-07 |
| ZA75713B (en) | 1976-01-28 |
| NO750400L (enrdf_load_html_response) | 1975-09-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI851317L (fi) | Enantioselektiivinen menetelmä optisesti aktiivisten -aryylialkaanikarboksyylihappojen valmistamiseksi | |
| DE69106977D1 (de) | Verfahren zur Herstellung von Nitrilen. | |
| GB1267016A (enrdf_load_html_response) | ||
| DE3561721D1 (en) | Process for the preparation of formic acid | |
| FR2260580A1 (en) | 5-Phenyl benzodiazepines prepn - from 2-(azidoacetylamino) benzophenones by conversion to phosphorus imine then cyclising | |
| ATE200896T1 (de) | Herstellung von säureamiden und metallierung von verbindungen | |
| ES482415A1 (es) | Procedimiento para la preparacion de la sal de 4-aminohex-5-inoico o una sal del mismo. | |
| ES8105709A1 (es) | Un procedimiento para la preparacion de derivados de azeti din-2-ona. | |
| ATE123027T1 (de) | Verfahren zur herstellung von (3,5- dioxopiperazinyl)-alkanen oder -alkenen. | |
| ES478706A1 (es) | Un metodo para producir un compuesto desmetilmaitansinoide. | |
| GB1301210A (en) | Process for the production of novel triazole compounds | |
| ES452377A1 (es) | Procedimiento para la preparacion de alfa amino-y metilmer- capto-butironitrilo. | |
| RO72882B (ro) | Procedeu de preparare a pirolului substituit | |
| GB1462498A (en) | Antimicrobial agents and their use | |
| FR2385683A1 (fr) | Procede de preparation de m-aminophenols utilisables pour la preparation de colorants | |
| IE38930B1 (en) | Production of 2,5-disubstituted benzamides | |
| ES2099014A1 (es) | Nuevos eteres de oxima quirales derivados del limoneno, procedimiento para su preparacion y aplicaciones. | |
| GB1463667A (en) | Process for preparing thioamides | |
| KR790000080B1 (en) | Process for preparation of 2-(phenoxyalkylthio) imidazoles | |
| KR970042499A (ko) | 4-(N-t-부톡시카르보닐)아미노메틸-1-(N-t-부톡시카르보닐)피롤리딘-3-올의 제조방법 | |
| GB1382756A (en) | Treating 3-methyl-3-hydroxycepham compounds |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |