FR2254336B1 - - Google Patents

Info

Publication number
FR2254336B1
FR2254336B1 FR7441513A FR7441513A FR2254336B1 FR 2254336 B1 FR2254336 B1 FR 2254336B1 FR 7441513 A FR7441513 A FR 7441513A FR 7441513 A FR7441513 A FR 7441513A FR 2254336 B1 FR2254336 B1 FR 2254336B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7441513A
Other versions
FR2254336A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of FR2254336A1 publication Critical patent/FR2254336A1/fr
Application granted granted Critical
Publication of FR2254336B1 publication Critical patent/FR2254336B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7441513A 1973-12-17 1974-12-17 Expired FR2254336B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP48139579A JPS5240B2 (fr) 1973-12-17 1973-12-17

Publications (2)

Publication Number Publication Date
FR2254336A1 FR2254336A1 (fr) 1975-07-11
FR2254336B1 true FR2254336B1 (fr) 1977-09-09

Family

ID=15248533

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7441513A Expired FR2254336B1 (fr) 1973-12-17 1974-12-17

Country Status (5)

Country Link
US (1) US4021449A (fr)
JP (1) JPS5240B2 (fr)
DE (1) DE2459616C3 (fr)
FR (1) FR2254336B1 (fr)
GB (1) GB1488129A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100512879C (zh) * 1999-04-23 2009-07-15 阿尔萨公司 用于脂质体中的有可裂解键的缀合物

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5240B2 (fr) * 1973-12-17 1977-01-05
JPS5439098A (en) * 1977-08-31 1979-03-24 Kyowa Hakko Kogyo Co Ltd Mitomycin c derivatives
JPS5925327A (ja) * 1982-07-31 1984-02-09 Hidematsu Hirai 抗腫瘍性複合体の製造方法
EP0179092A4 (fr) * 1984-04-10 1987-08-05 Baxter Travenol Lab Solutions de mitomycine.
US4720543A (en) * 1985-06-06 1988-01-19 Georgetown University 1a-7-substituted derivatives of mitomycin and uses thereof
JPH04500513A (ja) * 1988-08-23 1992-01-30 ジョージタウン・ユニバーシティー 低骨髄毒性マイトマイシン誘導体、その製造方法およびその使用
US5091523A (en) * 1990-04-25 1992-02-25 Georgetown University Mitomycin derivatives having reduced bone marrow toxicity, processes for their preparation, and the uses thereof
US7303760B2 (en) 1999-04-23 2007-12-04 Alza Corporation Method for treating multi-drug resistant tumors
US7238368B2 (en) * 1999-04-23 2007-07-03 Alza Corporation Releasable linkage and compositions containing same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL129868C (fr) * 1963-06-07
DE1570029A1 (de) * 1964-07-09 1970-04-09 Kyowa Hakko Kogyo Kk Verfahren zur Herstellung von Mitosanverbindungen
CH439311A (fr) * 1964-08-25 1967-07-15 Kyowa Hakko Kogyo Co Limited Procédé pour préparer une mitomycine C 1a-acylée
JPS5240B2 (fr) * 1973-12-17 1977-01-05

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100512879C (zh) * 1999-04-23 2009-07-15 阿尔萨公司 用于脂质体中的有可裂解键的缀合物

Also Published As

Publication number Publication date
FR2254336A1 (fr) 1975-07-11
DE2459616A1 (de) 1975-06-26
JPS5240B2 (fr) 1977-01-05
DE2459616C3 (de) 1981-10-22
JPS5089398A (fr) 1975-07-17
DE2459616B2 (de) 1980-11-27
US4021449A (en) 1977-05-03
GB1488129A (en) 1977-10-05

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Legal Events

Date Code Title Description
ST Notification of lapse