FR2245354A1 - N-Benzoyl-N,N-diethyl ethylene diamines - and their N-oxides and quat. ammonium iodides, are antiemetics, choleretics and laxatives - Google Patents
N-Benzoyl-N,N-diethyl ethylene diamines - and their N-oxides and quat. ammonium iodides, are antiemetics, choleretics and laxativesInfo
- Publication number
- FR2245354A1 FR2245354A1 FR7430459A FR7430459A FR2245354A1 FR 2245354 A1 FR2245354 A1 FR 2245354A1 FR 7430459 A FR7430459 A FR 7430459A FR 7430459 A FR7430459 A FR 7430459A FR 2245354 A1 FR2245354 A1 FR 2245354A1
- Authority
- FR
- France
- Prior art keywords
- choleretics
- laxatives
- antiemetics
- quat
- benzoyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000003474 anti-emetic effect Effects 0.000 title abstract 2
- 239000002111 antiemetic agent Substances 0.000 title abstract 2
- 229940125683 antiemetic agent Drugs 0.000 title abstract 2
- 239000008141 laxative Substances 0.000 title abstract 2
- 229940125722 laxative agent Drugs 0.000 title abstract 2
- PUAQLLVFLMYYJJ-UHFFFAOYSA-N 2-aminopropiophenone Chemical compound CC(N)C(=O)C1=CC=CC=C1 PUAQLLVFLMYYJJ-UHFFFAOYSA-N 0.000 title 1
- 150000001204 N-oxides Chemical class 0.000 title 1
- UKFWSNCTAHXBQN-UHFFFAOYSA-N ammonium iodide Chemical class [NH4+].[I-] UKFWSNCTAHXBQN-UHFFFAOYSA-N 0.000 title 1
- 230000001989 choleretic effect Effects 0.000 title 1
- -1 benzoylethylene diamine Chemical class 0.000 abstract 2
- HVTICUPFWKNHNG-UHFFFAOYSA-N iodoethane Chemical compound CCI HVTICUPFWKNHNG-UHFFFAOYSA-N 0.000 abstract 2
- BZSXEZOLBIJVQK-UHFFFAOYSA-N 2-methylsulfonylbenzoic acid Chemical compound CS(=O)(=O)C1=CC=CC=C1C(O)=O BZSXEZOLBIJVQK-UHFFFAOYSA-N 0.000 abstract 1
- OLJXRTRRJSMURJ-UHFFFAOYSA-N 4-amino-2-methoxybenzoic acid Chemical compound COC1=CC(N)=CC=C1C(O)=O OLJXRTRRJSMURJ-UHFFFAOYSA-N 0.000 abstract 1
- TUCNEACPLKLKNU-UHFFFAOYSA-N acetyl Chemical compound C[C]=O TUCNEACPLKLKNU-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000003591 anti-choleraic effect Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- INQOMBQAUSQDDS-UHFFFAOYSA-N iodomethane Chemical compound IC INQOMBQAUSQDDS-UHFFFAOYSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- TTWJBBZEZQICBI-UHFFFAOYSA-N metoclopramide Chemical compound CCN(CC)CCNC(=O)C1=CC(Cl)=C(N)C=C1OC TTWJBBZEZQICBI-UHFFFAOYSA-N 0.000 abstract 1
- 229960004503 metoclopramide Drugs 0.000 abstract 1
- UDGSVBYJWHOHNN-UHFFFAOYSA-N n',n'-diethylethane-1,2-diamine Chemical compound CCN(CC)CCN UDGSVBYJWHOHNN-UHFFFAOYSA-N 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 231100001274 therapeutic index Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES419284A ES419284A1 (es) | 1973-09-27 | 1973-09-27 | Procedimiento para la obtencion de derivados de benzoileti-lendiaminas sustituidas. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2245354A1 true FR2245354A1 (en) | 1975-04-25 |
| FR2245354B1 FR2245354B1 (enrdf_load_stackoverflow) | 1978-07-28 |
Family
ID=8465128
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7430459A Granted FR2245354A1 (en) | 1973-09-27 | 1974-09-09 | N-Benzoyl-N,N-diethyl ethylene diamines - and their N-oxides and quat. ammonium iodides, are antiemetics, choleretics and laxatives |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JPS5076039A (enrdf_load_stackoverflow) |
| ES (1) | ES419284A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2245354A1 (enrdf_load_stackoverflow) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1407055A (fr) * | 1963-03-05 | 1965-07-30 | Ile De France | Nouveau procédé de préparation de benzamides substitués |
| JPS4857950A (enrdf_load_stackoverflow) * | 1971-11-27 | 1973-08-14 |
-
1973
- 1973-09-27 ES ES419284A patent/ES419284A1/es not_active Expired
-
1974
- 1974-09-09 FR FR7430459A patent/FR2245354A1/fr active Granted
- 1974-09-27 JP JP49111369A patent/JPS5076039A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2245354B1 (enrdf_load_stackoverflow) | 1978-07-28 |
| JPS5076039A (enrdf_load_stackoverflow) | 1975-06-21 |
| ES419284A1 (es) | 1976-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |