FR2224448A1 - N-(substd alkyl)-2-alk(enyl)oxybenzamides - antiemetics digestion-regulators and psychotropics - Google Patents

N-(substd alkyl)-2-alk(enyl)oxybenzamides - antiemetics digestion-regulators and psychotropics

Info

Publication number
FR2224448A1
FR2224448A1 FR7312392A FR7312392A FR2224448A1 FR 2224448 A1 FR2224448 A1 FR 2224448A1 FR 7312392 A FR7312392 A FR 7312392A FR 7312392 A FR7312392 A FR 7312392A FR 2224448 A1 FR2224448 A1 FR 2224448A1
Authority
FR
France
Prior art keywords
alkyl
oxybenzamides
psychotropics
antiemetics
enyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7312392A
Other languages
French (fr)
Other versions
FR2224448B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ILE DE FRANCE ETUDES SCIENTIFIQU FR
Original Assignee
ILE DE FRANCE ETUDES SCIENTIFIQU FR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ILE DE FRANCE ETUDES SCIENTIFIQU FR filed Critical ILE DE FRANCE ETUDES SCIENTIFIQU FR
Priority to FR7312392A priority Critical patent/FR2224448A1/en
Priority to PH14664*UA priority patent/PH9265A/en
Priority to CS769273A priority patent/CS174898B2/cs
Priority to DE2327414A priority patent/DE2327414C2/en
Priority to CS769175A priority patent/CS174897B2/cs
Priority to JP6076573A priority patent/JPS5537545B2/ja
Priority to YU01421/73A priority patent/YU39107B/en
Priority to BG23737A priority patent/BG21854A3/xx
Priority to CS3876A priority patent/CS174886B2/cs
Priority to IE883/76A priority patent/IE37728B1/en
Priority to HUSO1081A priority patent/HU168115B/hu
Priority to HUSO1147A priority patent/HU169275B/hu
Priority to IL42400A priority patent/IL42400A/en
Priority to IE866/73A priority patent/IE37726B1/en
Priority to IL48880A priority patent/IL48880A/en
Priority to IE882/76A priority patent/IE37727B1/en
Priority to CH785973A priority patent/CH575913A5/xx
Priority to HUSO1148A priority patent/HU168989B/hu
Priority to BE1005109A priority patent/BE800234A/en
Priority to RO197374983A priority patent/RO73007A/en
Priority to DD171219A priority patent/DD109617A5/xx
Priority to KR7300889A priority patent/KR780000266B1/en
Priority to GB2627373A priority patent/GB1422221A/en
Priority to GB3253875A priority patent/GB1422223A/en
Priority to LU67729A priority patent/LU67729A1/xx
Priority to ES415454A priority patent/ES415454A1/en
Priority to CA172,965A priority patent/CA1016175A/en
Priority to GB582375A priority patent/GB1422222A/en
Priority to JP9234773A priority patent/JPS5069021A/ja
Priority to JP48092346A priority patent/JPS5070323A/ja
Priority to AU60514/73A priority patent/AU476711B2/en
Publication of FR2224448A1 publication Critical patent/FR2224448A1/en
Priority to IL48880A priority patent/IL48880A0/en
Priority to CA261,553A priority patent/CA1017745A/en
Priority to CA261,552A priority patent/CA1017343A/en
Application granted granted Critical
Publication of FR2224448B1 publication Critical patent/FR2224448B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Cpds. of formula (I): (where R1 is H or Me; B is 1-4C alkyl or alkenyl; X is H, NO2, acylamino or NH2; Y is H, halogen or SO2R2; R2 is NH2, mono- or dialkylamino, 1-5C alkyl or haloalkyl; n =3; A is (a) NR3R4, where R3 and R4 are lower alkyl or NR3R4 is a heterocycle, or (b) a gp. of formula: where R is 1-4C alkyl or alkenyl and m =4) and their acid-addn. salts and quat. ammonium derivs. are prepd. by reacting H2N(CHR1)nA with CS2, reacting the resulting cpd. HS-CS-HN(CHR1)nA with a substance capable of forming a volatile or insol. cpd. with S, and condensing the resulting cpd. SCN(CHR1)nA with the corresp. 2-OB-4X-5Y-benzoic acid.
FR7312392A 1972-06-02 1973-04-05 N-(substd alkyl)-2-alk(enyl)oxybenzamides - antiemetics digestion-regulators and psychotropics Granted FR2224448A1 (en)

Priority Applications (34)

Application Number Priority Date Filing Date Title
FR7312392A FR2224448A1 (en) 1973-04-05 1973-04-05 N-(substd alkyl)-2-alk(enyl)oxybenzamides - antiemetics digestion-regulators and psychotropics
PH14664*UA PH9265A (en) 1972-06-02 1973-05-28 A method of preparing 2-alkoxy-4,5-substituted benzamides
DE2327414A DE2327414C2 (en) 1972-06-02 1973-05-29 Process for the preparation of N- (diethylaminoethyl) -2-methoxy-5-methylsulfonylbenzamide and its addition salts
CS769175A CS174897B2 (en) 1972-06-02 1973-05-29
JP6076573A JPS5537545B2 (en) 1972-06-02 1973-05-29
YU01421/73A YU39107B (en) 1972-06-02 1973-05-29 Process for obtaining 2-methoxy-4,5-subst.benzamides
BG23737A BG21854A3 (en) 1972-06-02 1973-05-29
CS3876A CS174886B2 (en) 1972-06-02 1973-05-29
CS769273A CS174898B2 (en) 1972-06-02 1973-05-29
HUSO1148A HU168989B (en) 1973-04-05 1973-05-30
HUSO1147A HU169275B (en) 1973-04-05 1973-05-30
IL42400A IL42400A (en) 1972-06-02 1973-05-30 Preparation of 2-alkoxy or alkenyloxy-4,5-substituted-aminoalkylbenzamides and certain new intermediates therefor
IE866/73A IE37726B1 (en) 1972-06-02 1973-05-30 Preparation of 2-alkoxybenzamides
IL48880A IL48880A (en) 1972-06-02 1973-05-30 Isothiocyanates and their preparation
IE882/76A IE37727B1 (en) 1972-06-02 1973-05-30 Dithiocarbamates
CH785973A CH575913A5 (en) 1972-06-02 1973-05-30
IE883/76A IE37728B1 (en) 1972-06-02 1973-05-30 Isothiocyanates
BE1005109A BE800234A (en) 1972-06-02 1973-05-30 NEW PROCESS FOR THE PREPARATION OF 2-ALCOXY-4,5-BENZAMIDE SUBSTITUTES,
HUSO1081A HU168115B (en) 1972-06-02 1973-05-30
RO197374983A RO73007A (en) 1972-06-02 1973-05-31 PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-METOXYBENZAMIDES IN POSITIONS 4,5
DD171219A DD109617A5 (en) 1972-06-02 1973-05-31
KR7300889A KR780000266B1 (en) 1973-04-05 1973-06-01 Method of preparing 2-alkoxy 45-substituted benzanides
GB2627373A GB1422221A (en) 1972-06-02 1973-06-01 Preparation of 2-alkoxybenzamides
GB3253875A GB1422223A (en) 1972-06-02 1973-06-01 Isothiocyanates
LU67729A LU67729A1 (en) 1972-06-02 1973-06-01
ES415454A ES415454A1 (en) 1973-04-05 1973-06-01 Method of preparation of 2-alcoxy-benzamides replaced in positions 4 and 5. (Machine-translation by Google Translate, not legally binding)
CA172,965A CA1016175A (en) 1972-06-02 1973-06-01 Process of preparation of 2-alcoxy4-5 subsituted benzamides
GB582375A GB1422222A (en) 1972-06-02 1973-06-01 Dithiocarbamates
JP48092346A JPS5070323A (en) 1972-06-02 1973-08-17
JP9234773A JPS5069021A (en) 1972-06-02 1973-08-17
AU60514/73A AU476711B2 (en) 1972-06-02 1973-09-20 New method of preparing 2-alkoxy 4-5 substituted benzamides
IL48880A IL48880A0 (en) 1972-06-02 1976-01-20 Novel isothiocyanates and their preparation
CA261,553A CA1017745A (en) 1972-06-02 1976-09-20 Isothiocyanate derivatives and the preparation thereof
CA261,552A CA1017343A (en) 1972-06-02 1976-09-20 Process for preparing dithiocarbamic acid derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7312392A FR2224448A1 (en) 1973-04-05 1973-04-05 N-(substd alkyl)-2-alk(enyl)oxybenzamides - antiemetics digestion-regulators and psychotropics

Publications (2)

Publication Number Publication Date
FR2224448A1 true FR2224448A1 (en) 1974-10-31
FR2224448B1 FR2224448B1 (en) 1977-12-30

Family

ID=9117504

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7312392A Granted FR2224448A1 (en) 1972-06-02 1973-04-05 N-(substd alkyl)-2-alk(enyl)oxybenzamides - antiemetics digestion-regulators and psychotropics

Country Status (4)

Country Link
KR (1) KR780000266B1 (en)
ES (1) ES415454A1 (en)
FR (1) FR2224448A1 (en)
HU (2) HU169275B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2305176A1 (en) * 1975-03-28 1976-10-22 Ile De France NEW DRUG BASED ON N- (DIETHYLAMINOETHYL) 2-METHOXY-5-METHYL-SULFONYL BENZAMIDE

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2305176A1 (en) * 1975-03-28 1976-10-22 Ile De France NEW DRUG BASED ON N- (DIETHYLAMINOETHYL) 2-METHOXY-5-METHYL-SULFONYL BENZAMIDE

Also Published As

Publication number Publication date
HU169275B (en) 1976-10-28
KR780000266B1 (en) 1978-07-24
ES415454A1 (en) 1976-02-16
HU168989B (en) 1976-08-28
FR2224448B1 (en) 1977-12-30

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