FR2220273A1 - Sulphur-contg. N-substd nicotinamide derivs - for curing effects of hepatic diseases and reducing arterial pressure - Google Patents

Sulphur-contg. N-substd nicotinamide derivs - for curing effects of hepatic diseases and reducing arterial pressure

Info

Publication number
FR2220273A1
FR2220273A1 FR7411339A FR7411339A FR2220273A1 FR 2220273 A1 FR2220273 A1 FR 2220273A1 FR 7411339 A FR7411339 A FR 7411339A FR 7411339 A FR7411339 A FR 7411339A FR 2220273 A1 FR2220273 A1 FR 2220273A1
Authority
FR
France
Prior art keywords
substd
derivs
contg
nicotinamide
sulphur
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7411339A
Other languages
French (fr)
Other versions
FR2220273B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Publication of FR2220273A1 publication Critical patent/FR2220273A1/en
Application granted granted Critical
Publication of FR2220273B1 publication Critical patent/FR2220273B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

The novel cpds. of formula (I):-(where R is H or opt. substd. alkyl or alkaryl; R1 is an opt. substd. linear or branched aliphatic chain, or an opt. substd. 3-6- membered ring opt. contng. heteroatoms; R2 is H, opt. substd. alkyl or alkaryl, or COR), prepd. by reacting nicotinoyl chloride hydrochloride with the corresp. amine.
FR7411339A 1973-03-08 1974-03-29 Sulphur-contg. N-substd nicotinamide derivs - for curing effects of hepatic diseases and reducing arterial pressure Granted FR2220273A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT4867573A IT1056032B (en) 1973-03-08 1973-03-08 NICOTINIC ACID DERIVATIVES WITH VARIOUSLY REPLACED AMINES

Publications (2)

Publication Number Publication Date
FR2220273A1 true FR2220273A1 (en) 1974-10-04
FR2220273B1 FR2220273B1 (en) 1977-05-06

Family

ID=11267982

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7411339A Granted FR2220273A1 (en) 1973-03-08 1974-03-29 Sulphur-contg. N-substd nicotinamide derivs - for curing effects of hepatic diseases and reducing arterial pressure

Country Status (2)

Country Link
FR (1) FR2220273A1 (en)
IT (1) IT1056032B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2526431A1 (en) * 1982-05-10 1983-11-10 Sanofi Sa N-2-guanidino-thiazolyl methyl:thio-ethyl benzamide and nicotinamide - histamine H2 receptor blockers, used to treat ulcers
EP0094303A1 (en) * 1982-05-10 1983-11-16 Sanofi S.A. Amides, their salts, process for their preparation and pharmaceutical compositions containing them

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2526431A1 (en) * 1982-05-10 1983-11-10 Sanofi Sa N-2-guanidino-thiazolyl methyl:thio-ethyl benzamide and nicotinamide - histamine H2 receptor blockers, used to treat ulcers
EP0094303A1 (en) * 1982-05-10 1983-11-16 Sanofi S.A. Amides, their salts, process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
IT1056032B (en) 1982-01-30
FR2220273B1 (en) 1977-05-06

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Legal Events

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