FR2207715A1 - (Leu3 leu4)-arginine and lysine-vasopressins - natriuretics with low hypertensive activity useful for treatment of oedema - Google Patents

(Leu3 leu4)-arginine and lysine-vasopressins - natriuretics with low hypertensive activity useful for treatment of oedema

Info

Publication number
FR2207715A1
FR2207715A1 FR7341563A FR7341563A FR2207715A1 FR 2207715 A1 FR2207715 A1 FR 2207715A1 FR 7341563 A FR7341563 A FR 7341563A FR 7341563 A FR7341563 A FR 7341563A FR 2207715 A1 FR2207715 A1 FR 2207715A1
Authority
FR
France
Prior art keywords
natriuretics
vasopressins
leu4
leu3
oedema
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7341563A
Other languages
English (en)
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2207715A1 publication Critical patent/FR2207715A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/16—Oxytocins; Vasopressins; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR7341563A 1972-11-24 1973-11-22 (Leu3 leu4)-arginine and lysine-vasopressins - natriuretics with low hypertensive activity useful for treatment of oedema Withdrawn FR2207715A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1718472 1972-11-24

Publications (1)

Publication Number Publication Date
FR2207715A1 true FR2207715A1 (en) 1974-06-21

Family

ID=4423420

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7341563A Withdrawn FR2207715A1 (en) 1972-11-24 1973-11-22 (Leu3 leu4)-arginine and lysine-vasopressins - natriuretics with low hypertensive activity useful for treatment of oedema

Country Status (7)

Country Link
JP (1) JPS4982682A (enExample)
AU (1) AU6147073A (enExample)
BE (1) BE807704A (enExample)
DE (1) DE2357334A1 (enExample)
FR (1) FR2207715A1 (enExample)
NL (1) NL7314486A (enExample)
ZA (1) ZA737898B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0151016A3 (en) * 1984-01-26 1987-04-01 Medical College of Ohio Arginine vasopressin antagonists
EP0189326A3 (en) * 1985-01-23 1988-10-26 Medical College of Ohio Derivatives of arginine vasopressin antagonists

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1133648C (zh) * 1997-07-31 2004-01-07 伊兰药品公司 抑制vla-4介导的白细胞粘附的取代的苯丙氨酸型化合物
US6362341B1 (en) 1997-07-31 2002-03-26 Athena Neurosciences, Inc. Benzyl compounds which inhibit leukocyte adhesion mediated by VLA-4
US6583139B1 (en) 1997-07-31 2003-06-24 Eugene D. Thorsett Compounds which inhibit leukocyte adhesion mediated by VLA-4
US6291453B1 (en) 1997-07-31 2001-09-18 Athena Neurosciences, Inc. 4-amino-phenylalanine type compounds which inhibit leukocyte adhesion mediated by VLA-4
US6489300B1 (en) 1997-07-31 2002-12-03 Eugene D. Thorsett Carbamyloxy compounds which inhibit leukocyte adhesion mediated by VLA-4
US6423688B1 (en) 1997-07-31 2002-07-23 Athena Neurosciences, Inc. Dipeptide and related compounds which inhibit leukocyte adhesion mediated by VLA-4
US6492421B1 (en) 1997-07-31 2002-12-10 Athena Neurosciences, Inc. Substituted phenylalanine type compounds which inhibit leukocyte adhesion mediated by VLA-4
US6939855B2 (en) 1997-07-31 2005-09-06 Elan Pharmaceuticals, Inc. Anti-inflammatory compositions and method
US6559127B1 (en) 1997-07-31 2003-05-06 Athena Neurosciences, Inc. Compounds which inhibit leukocyte adhesion mediated by VLA-4
US7030114B1 (en) 1997-07-31 2006-04-18 Elan Pharmaceuticals, Inc. Compounds which inhibit leukocyte adhesion mediated by VLA-4
US6407066B1 (en) 1999-01-26 2002-06-18 Elan Pharmaceuticals, Inc. Pyroglutamic acid derivatives and related compounds which inhibit leukocyte adhesion mediated by VLA-4

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0151016A3 (en) * 1984-01-26 1987-04-01 Medical College of Ohio Arginine vasopressin antagonists
EP0189326A3 (en) * 1985-01-23 1988-10-26 Medical College of Ohio Derivatives of arginine vasopressin antagonists

Also Published As

Publication number Publication date
AU6147073A (en) 1975-04-17
ZA737898B (en) 1974-07-31
NL7314486A (enExample) 1974-05-28
DE2357334A1 (de) 1974-06-06
BE807704A (fr) 1974-05-24
JPS4982682A (enExample) 1974-08-08

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Legal Events

Date Code Title Description
ST Notification of lapse