FR2201287A1 - Epoxidation using hexafluoroacetone hydroperoxide - for treatment of unsatd. cyclic cpds esp steroids - Google Patents

Epoxidation using hexafluoroacetone hydroperoxide - for treatment of unsatd. cyclic cpds esp steroids

Info

Publication number
FR2201287A1
FR2201287A1 FR7234136A FR7234136A FR2201287A1 FR 2201287 A1 FR2201287 A1 FR 2201287A1 FR 7234136 A FR7234136 A FR 7234136A FR 7234136 A FR7234136 A FR 7234136A FR 2201287 A1 FR2201287 A1 FR 2201287A1
Authority
FR
France
Prior art keywords
unsatd
epoxidation
esp
steroids
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7234136A
Other languages
English (en)
Other versions
FR2201287B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7234136A priority Critical patent/FR2201287A1/fr
Publication of FR2201287A1 publication Critical patent/FR2201287A1/fr
Application granted granted Critical
Publication of FR2201287B1 publication Critical patent/FR2201287B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D301/00Preparation of oxiranes
    • C07D301/02Synthesis of the oxirane ring
    • C07D301/03Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds
    • C07D301/19Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds with organic hydroperoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0066Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0074Esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005Ketals
    • C07J21/006Ketals at position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
FR7234136A 1972-09-27 1972-09-27 Epoxidation using hexafluoroacetone hydroperoxide - for treatment of unsatd. cyclic cpds esp steroids Granted FR2201287A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7234136A FR2201287A1 (en) 1972-09-27 1972-09-27 Epoxidation using hexafluoroacetone hydroperoxide - for treatment of unsatd. cyclic cpds esp steroids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7234136A FR2201287A1 (en) 1972-09-27 1972-09-27 Epoxidation using hexafluoroacetone hydroperoxide - for treatment of unsatd. cyclic cpds esp steroids

Publications (2)

Publication Number Publication Date
FR2201287A1 true FR2201287A1 (en) 1974-04-26
FR2201287B1 FR2201287B1 (fr) 1976-03-12

Family

ID=9104826

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7234136A Granted FR2201287A1 (en) 1972-09-27 1972-09-27 Epoxidation using hexafluoroacetone hydroperoxide - for treatment of unsatd. cyclic cpds esp steroids

Country Status (1)

Country Link
FR (1) FR2201287A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0005100A1 (fr) * 1978-04-19 1979-10-31 Roussel-Uclaf Nouveau réactif d'époxydation et son application à l'époxydation de composés organiques acycliques, cycliques ou polycycliques comportant au moins une insaturation éthylénique
WO1996030390A2 (fr) * 1995-03-30 1996-10-03 The United States Of America, Represented By The Secretary, Department Of Health And Human Services PROCEDE DE PREPARATION DE 17α-ACETOXY-11β-(4-N,N-DIMETHYLAMINOPHENYL)-19-NORPREGNA-4,9-DIENE-3,20-DIONE, INTERMEDIAIRES UTILISES DANS LE PROCEDE, ET PROCEDES DE PREPARATION DE CES INTERMEDIAIRES
US5955622A (en) * 1995-11-30 1999-09-21 Akzo Nobel, N.V. Method for the preparation of steroid derivative ketal
WO2015089338A2 (fr) 2013-12-11 2015-06-18 Sloan-Kettering Institute For Cancer Research Inhibiteurs de glucocorticoïdes pour le traitement du cancer de la prostate

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0005100A1 (fr) * 1978-04-19 1979-10-31 Roussel-Uclaf Nouveau réactif d'époxydation et son application à l'époxydation de composés organiques acycliques, cycliques ou polycycliques comportant au moins une insaturation éthylénique
WO1996030390A2 (fr) * 1995-03-30 1996-10-03 The United States Of America, Represented By The Secretary, Department Of Health And Human Services PROCEDE DE PREPARATION DE 17α-ACETOXY-11β-(4-N,N-DIMETHYLAMINOPHENYL)-19-NORPREGNA-4,9-DIENE-3,20-DIONE, INTERMEDIAIRES UTILISES DANS LE PROCEDE, ET PROCEDES DE PREPARATION DE CES INTERMEDIAIRES
WO1996030390A3 (fr) * 1995-03-30 1997-01-09 Us Health PROCEDE DE PREPARATION DE 17α-ACETOXY-11β-(4-N,N-DIMETHYLAMINOPHENYL)-19-NORPREGNA-4,9-DIENE-3,20-DIONE, INTERMEDIAIRES UTILISES DANS LE PROCEDE, ET PROCEDES DE PREPARATION DE CES INTERMEDIAIRES
US5929262A (en) * 1995-03-30 1999-07-27 The United States Of America As Represented By The Department Of Health And Human Services Method for preparing 17α-acetoxy-11β-(4-N, N-dimethylaminophyl)-19-Norpregna-4,9-diene-3, 20-dione, intermediates useful in the method, and methods for the preparation of such intermediates
AU716894B2 (en) * 1995-03-30 2000-03-09 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Method for preparing 17alpha-acetoxy-11beta-(4-N,N-dimethyla minophenyl)-19-norpregna-4,9-diene-3,20-dione, intermediates useful in the method, and methods for the preparation of such intermediates
US5955622A (en) * 1995-11-30 1999-09-21 Akzo Nobel, N.V. Method for the preparation of steroid derivative ketal
WO2015089338A2 (fr) 2013-12-11 2015-06-18 Sloan-Kettering Institute For Cancer Research Inhibiteurs de glucocorticoïdes pour le traitement du cancer de la prostate

Also Published As

Publication number Publication date
FR2201287B1 (fr) 1976-03-12

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Legal Events

Date Code Title Description
ST Notification of lapse