FR2189035A1 - Substd benzoylethylene diamine derivs - with antiemetic and choleretic activity - Google Patents
Substd benzoylethylene diamine derivs - with antiemetic and choleretic activityInfo
- Publication number
- FR2189035A1 FR2189035A1 FR7321850A FR7321850A FR2189035A1 FR 2189035 A1 FR2189035 A1 FR 2189035A1 FR 7321850 A FR7321850 A FR 7321850A FR 7321850 A FR7321850 A FR 7321850A FR 2189035 A1 FR2189035 A1 FR 2189035A1
- Authority
- FR
- France
- Prior art keywords
- coch3
- derivs
- treatment
- benzoylethylene
- substd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000003474 anti-emetic effect Effects 0.000 title 1
- 239000002111 antiemetic agent Substances 0.000 title 1
- -1 benzoylethylene diamine Chemical class 0.000 title 1
- 230000001989 choleretic effect Effects 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- INQOMBQAUSQDDS-UHFFFAOYSA-N iodomethane Chemical compound IC INQOMBQAUSQDDS-UHFFFAOYSA-N 0.000 abstract 3
- 102100038916 Caspase-5 Human genes 0.000 abstract 2
- 101100112336 Homo sapiens CASP5 gene Proteins 0.000 abstract 2
- 101100273286 Mus musculus Casp4 gene Proteins 0.000 abstract 2
- GBOUQGUQUUPGLO-UHFFFAOYSA-N 2-chloro-5-methoxyaniline Chemical compound COC1=CC=C(Cl)C(N)=C1 GBOUQGUQUUPGLO-UHFFFAOYSA-N 0.000 abstract 1
- WETWJCDKMRHUPV-UHFFFAOYSA-N acetyl chloride Chemical compound CC(Cl)=O WETWJCDKMRHUPV-UHFFFAOYSA-N 0.000 abstract 1
- 239000012346 acetyl chloride Substances 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 230000001079 digestive effect Effects 0.000 abstract 1
- HVTICUPFWKNHNG-UHFFFAOYSA-N iodoethane Chemical compound CCI HVTICUPFWKNHNG-UHFFFAOYSA-N 0.000 abstract 1
- FNDSFWLXHWZIQR-UHFFFAOYSA-N n,n-diethyl-2-isocyanatoethanamine Chemical compound CCN(CC)CCN=C=O FNDSFWLXHWZIQR-UHFFFAOYSA-N 0.000 abstract 1
- HQQWOFSQIIPRJY-UHFFFAOYSA-N n-(2-chloro-5-methoxyphenyl)acetamide Chemical compound COC1=CC=C(Cl)C(NC(C)=O)=C1 HQQWOFSQIIPRJY-UHFFFAOYSA-N 0.000 abstract 1
- 239000007800 oxidant agent Substances 0.000 abstract 1
- 230000002040 relaxant effect Effects 0.000 abstract 1
- 210000004514 sphincter of oddi Anatomy 0.000 abstract 1
- 238000002636 symptomatic treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
- C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
- C07C291/04—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds containing amino-oxide bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES404497A ES404497A1 (es) | 1972-06-20 | 1972-06-20 | Procedimiento para la obtencion de derivados de benzoileti-lendiaminas sustituidas. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2189035A1 true FR2189035A1 (en) | 1974-01-25 |
| FR2189035B1 FR2189035B1 (enExample) | 1976-12-31 |
Family
ID=8461615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7321850A Granted FR2189035A1 (en) | 1972-06-20 | 1973-06-15 | Substd benzoylethylene diamine derivs - with antiemetic and choleretic activity |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5644065B2 (enExample) |
| AR (1) | AR201912A1 (enExample) |
| DE (1) | DE2330425B2 (enExample) |
| ES (1) | ES404497A1 (enExample) |
| FR (1) | FR2189035A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0002531D0 (sv) * | 2000-07-05 | 2000-07-05 | Active Biotech Ab | Immune Enhancement |
-
1972
- 1972-06-20 ES ES404497A patent/ES404497A1/es not_active Expired
-
1973
- 1973-02-09 AR AR246516A patent/AR201912A1/es active
- 1973-06-15 FR FR7321850A patent/FR2189035A1/fr active Granted
- 1973-06-15 DE DE19732330425 patent/DE2330425B2/de not_active Withdrawn
- 1973-06-20 JP JP6966973A patent/JPS5644065B2/ja not_active Expired
Non-Patent Citations (1)
| Title |
|---|
| HOUBEN WEYL METHODEN DER ORGANISCHEN CHEMIE,BAND III, PAGE 415) * |
Also Published As
| Publication number | Publication date |
|---|---|
| ES404497A1 (es) | 1975-06-01 |
| JPS4961134A (enExample) | 1974-06-13 |
| DE2330425A1 (de) | 1974-01-17 |
| JPS5644065B2 (enExample) | 1981-10-16 |
| FR2189035B1 (enExample) | 1976-12-31 |
| DE2330425B2 (de) | 1976-02-19 |
| AR201912A1 (es) | 1975-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |