FR2182943A1 - Cis-dihalo-bis(ethyleneimine) platinum (ii) derivs - anti-cancer agents - Google Patents
Cis-dihalo-bis(ethyleneimine) platinum (ii) derivs - anti-cancer agentsInfo
- Publication number
- FR2182943A1 FR2182943A1 FR7312664A FR7312664A FR2182943A1 FR 2182943 A1 FR2182943 A1 FR 2182943A1 FR 7312664 A FR7312664 A FR 7312664A FR 7312664 A FR7312664 A FR 7312664A FR 2182943 A1 FR2182943 A1 FR 2182943A1
- Authority
- FR
- France
- Prior art keywords
- derivs
- dihalo
- ethyleneimine
- cis
- platinum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- NOWKCMXCCJGMRR-UHFFFAOYSA-N Aziridine Chemical compound C1CN1 NOWKCMXCCJGMRR-UHFFFAOYSA-N 0.000 title 1
- 239000002246 antineoplastic agent Substances 0.000 title 1
- HRGDZIGMBDGFTC-UHFFFAOYSA-N platinum(2+) Chemical compound [Pt+2] HRGDZIGMBDGFTC-UHFFFAOYSA-N 0.000 title 1
- 229910006069 SO3H Inorganic materials 0.000 abstract 1
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 125000000020 sulfo group Chemical group O=S(=O)([*])O[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/22—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1635072 | 1972-04-10 | ||
| GB2138972 | 1972-05-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2182943A1 true FR2182943A1 (en) | 1973-12-14 |
| FR2182943B1 FR2182943B1 (enExample) | 1976-12-31 |
Family
ID=26251984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7312664A Granted FR2182943A1 (en) | 1972-04-10 | 1973-04-09 | Cis-dihalo-bis(ethyleneimine) platinum (ii) derivs - anti-cancer agents |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS4913316A (enExample) |
| DE (1) | DE2318020A1 (enExample) |
| FR (1) | FR2182943A1 (enExample) |
| NL (1) | NL7304882A (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5171994A (enExample) * | 1974-12-17 | 1976-06-22 | Nippon Electric Co | |
| US4645661A (en) * | 1984-06-29 | 1987-02-24 | St. Jude Children's Research Hospital | Method for alleviating cisplatin-induced nephrotoxicity and dithiocarbamate compounds for effecting same |
| TWI315982B (en) | 2001-07-19 | 2009-10-21 | Novartis Ag | Combinations comprising epothilones and pharmaceutical uses thereof |
| CA2456348A1 (en) * | 2001-08-23 | 2003-03-06 | Yechezkel Barenholz | Platinum complexes and their uses in therapy |
| NZ572299A (en) | 2006-05-09 | 2010-07-30 | Novartis Ag | Combination comprising a substituted 3,5-diphenyl-1,2,4-triazole and a platinum compound and use thereof |
| US8246975B2 (en) | 2006-06-28 | 2012-08-21 | Ihi Corporation | Drug, drug guidance system, magnetic detection system, and drug design method |
| CN101918030B (zh) | 2007-11-09 | 2015-10-14 | 派瑞格恩医药公司 | 抗vegf抗体的组合物和方法 |
| US20090169484A1 (en) | 2007-12-28 | 2009-07-02 | Ihi Corporation | Iron-salen complex |
| JP5513405B2 (ja) | 2008-11-20 | 2014-06-04 | 株式会社Ｉｈｉ | 自己磁性金属サレン錯体化合物 |
-
1973
- 1973-04-09 FR FR7312664A patent/FR2182943A1/fr active Granted
- 1973-04-09 NL NL7304882A patent/NL7304882A/xx not_active Application Discontinuation
- 1973-04-10 JP JP48040779A patent/JPS4913316A/ja active Pending
- 1973-04-10 DE DE2318020A patent/DE2318020A1/de active Pending
Non-Patent Citations (1)
| Title |
|---|
| CHEMICAL ABSTRACTS", VOLUME 78, REF. 79753Q 1973 ) * |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2182943B1 (enExample) | 1976-12-31 |
| DE2318020A1 (de) | 1973-11-08 |
| NL7304882A (enExample) | 1973-10-12 |
| JPS4913316A (enExample) | 1974-02-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |