FR2140347A1 - 2-cinnamoyl-1-(2-hydroxyethyl) benzimidazoles - with vasodilator , hypotensive respiratory analeptic, diuretic and analgesic activity - Google Patents
2-cinnamoyl-1-(2-hydroxyethyl) benzimidazoles - with vasodilator , hypotensive respiratory analeptic, diuretic and analgesic activityInfo
- Publication number
- FR2140347A1 FR2140347A1 FR7121341A FR7121341A FR2140347A1 FR 2140347 A1 FR2140347 A1 FR 2140347A1 FR 7121341 A FR7121341 A FR 7121341A FR 7121341 A FR7121341 A FR 7121341A FR 2140347 A1 FR2140347 A1 FR 2140347A1
- Authority
- FR
- France
- Prior art keywords
- vasodilator
- hypotensive
- diuretic
- hydroxyethyl
- cinnamoyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000001953 Hypotension Diseases 0.000 title abstract 2
- 239000002269 analeptic agent Substances 0.000 title abstract 2
- 230000003555 analeptic effect Effects 0.000 title abstract 2
- 230000000202 analgesic effect Effects 0.000 title abstract 2
- 239000002934 diuretic Substances 0.000 title abstract 2
- 230000001882 diuretic effect Effects 0.000 title abstract 2
- 208000021822 hypotensive Diseases 0.000 title abstract 2
- 230000001077 hypotensive effect Effects 0.000 title abstract 2
- 230000000241 respiratory effect Effects 0.000 title abstract 2
- 229940124549 vasodilator Drugs 0.000 title abstract 2
- 239000003071 vasodilator agent Substances 0.000 title abstract 2
- RPYGRBSABAAGDQ-UHFFFAOYSA-N 1-[1-(2-hydroxyethyl)benzimidazol-2-yl]-3-phenylprop-2-en-1-one Chemical class C(C=CC1=CC=CC=C1)(=O)C1=NC2=C(N1CCO)C=CC=C2 RPYGRBSABAAGDQ-UHFFFAOYSA-N 0.000 title 1
- JHALMTNWEGYQFQ-UHFFFAOYSA-N 1-[1-(2-hydroxyethyl)benzimidazol-2-yl]ethanone Chemical compound C1=CC=C2N(CCO)C(C(=O)C)=NC2=C1 JHALMTNWEGYQFQ-UHFFFAOYSA-N 0.000 abstract 1
- 125000002941 2-furyl group Chemical group O1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000003935 benzaldehydes Chemical class 0.000 abstract 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7121341A FR2140347A1 (en) | 1971-06-11 | 1971-06-11 | 2-cinnamoyl-1-(2-hydroxyethyl) benzimidazoles - with vasodilator , hypotensive respiratory analeptic, diuretic and analgesic activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7121341A FR2140347A1 (en) | 1971-06-11 | 1971-06-11 | 2-cinnamoyl-1-(2-hydroxyethyl) benzimidazoles - with vasodilator , hypotensive respiratory analeptic, diuretic and analgesic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2140347A1 true FR2140347A1 (en) | 1973-01-19 |
| FR2140347B1 FR2140347B1 (cs) | 1974-08-30 |
Family
ID=9078529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7121341A Granted FR2140347A1 (en) | 1971-06-11 | 1971-06-11 | 2-cinnamoyl-1-(2-hydroxyethyl) benzimidazoles - with vasodilator , hypotensive respiratory analeptic, diuretic and analgesic activity |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2140347A1 (cs) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104140415A (zh) * | 2014-06-03 | 2014-11-12 | 中国医学科学院医药生物技术研究所 | 含有苯并五元不饱和杂环结构的α、β不饱和酮类化合物及其制备方法和应用 |
-
1971
- 1971-06-11 FR FR7121341A patent/FR2140347A1/fr active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104140415A (zh) * | 2014-06-03 | 2014-11-12 | 中国医学科学院医药生物技术研究所 | 含有苯并五元不饱和杂环结构的α、β不饱和酮类化合物及其制备方法和应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2140347B1 (cs) | 1974-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |