FR2135221A1 - Doxorubicin 14-esters prepn - by treating 14-bromodaunomycin with a salt of the corresp acid - Google Patents

Doxorubicin 14-esters prepn - by treating 14-bromodaunomycin with a salt of the corresp acid

Info

Publication number
FR2135221A1
FR2135221A1 FR7215548A FR7215548A FR2135221A1 FR 2135221 A1 FR2135221 A1 FR 2135221A1 FR 7215548 A FR7215548 A FR 7215548A FR 7215548 A FR7215548 A FR 7215548A FR 2135221 A1 FR2135221 A1 FR 2135221A1
Authority
FR
France
Prior art keywords
acid
salt
acids
bromodaunomycin
doxorubicin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7215548A
Other languages
English (en)
French (fr)
Other versions
FR2135221B1 (https=
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmaceutici Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia SpA filed Critical Farmaceutici Italia SpA
Publication of FR2135221A1 publication Critical patent/FR2135221A1/fr
Application granted granted Critical
Publication of FR2135221B1 publication Critical patent/FR2135221B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FR7215548A 1971-05-04 1972-05-02 Doxorubicin 14-esters prepn - by treating 14-bromodaunomycin with a salt of the corresp acid Granted FR2135221A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2403071 1971-05-04

Publications (2)

Publication Number Publication Date
FR2135221A1 true FR2135221A1 (en) 1972-12-15
FR2135221B1 FR2135221B1 (https=) 1978-03-03

Family

ID=11211575

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7215548A Granted FR2135221A1 (en) 1971-05-04 1972-05-02 Doxorubicin 14-esters prepn - by treating 14-bromodaunomycin with a salt of the corresp acid

Country Status (1)

Country Link
FR (1) FR2135221A1 (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2361417A1 (fr) * 1976-08-12 1978-03-10 Farmaceutici Italia Nouveaux derives d'adriamycine et procede pour les preparer
US4299822A (en) * 1980-06-09 1981-11-10 Sidney Farber Cancer Institute, Inc. N-Trifluoroacetyladriamycin-14-O-hemiglutarate and -hemiadipate and therapeutic compositions containing same
EP0424899A3 (en) * 1989-10-25 1991-09-18 Dong-A Pharm. Co., Ltd. Novel anthracycline glycoside derivatives and preparing method thereof
EP0746336A4 (en) * 1991-08-05 1996-07-26 Igen Inc PRECURRENT DRUGS ACTIVATED BY TARGETED CATALYTIC PROTEINS
US6258360B1 (en) 1989-05-04 2001-07-10 Igen International, Inc. Prodrugs activated by targeted catalytic proteins
US6702705B1 (en) 1988-05-04 2004-03-09 Igen International, Inc. Prodrugs activated by targeted catalytic proteins

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2007443A1 (https=) * 1968-04-12 1970-01-09 Farmaceutici Italia

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2007443A1 (https=) * 1968-04-12 1970-01-09 Farmaceutici Italia

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2361417A1 (fr) * 1976-08-12 1978-03-10 Farmaceutici Italia Nouveaux derives d'adriamycine et procede pour les preparer
US4299822A (en) * 1980-06-09 1981-11-10 Sidney Farber Cancer Institute, Inc. N-Trifluoroacetyladriamycin-14-O-hemiglutarate and -hemiadipate and therapeutic compositions containing same
US6702705B1 (en) 1988-05-04 2004-03-09 Igen International, Inc. Prodrugs activated by targeted catalytic proteins
US6258360B1 (en) 1989-05-04 2001-07-10 Igen International, Inc. Prodrugs activated by targeted catalytic proteins
EP0424899A3 (en) * 1989-10-25 1991-09-18 Dong-A Pharm. Co., Ltd. Novel anthracycline glycoside derivatives and preparing method thereof
EP0746336A4 (en) * 1991-08-05 1996-07-26 Igen Inc PRECURRENT DRUGS ACTIVATED BY TARGETED CATALYTIC PROTEINS

Also Published As

Publication number Publication date
FR2135221B1 (https=) 1978-03-03

Similar Documents

Publication Publication Date Title
FR2135221A1 (en) Doxorubicin 14-esters prepn - by treating 14-bromodaunomycin with a salt of the corresp acid
SE7409248L (sv) Forfarande for framstellning av alkalimetall- och ammoniuminsuliner.
ES8301626A1 (es) Un procedimiento mejorado para producir un preparado antimicrobiano de d-7(&-(4-hidroxi-6-metilnicotinamido)-4-hidroxi- fenilacetamido)-3-(1-metiltetrazol-5-il) tiometil-a3-cefem-4-carboxilato de sodio.
FR2113774A1 (en) Prepn of l-ornithine salts with org acids - using silver oxides
GB1418338A (en) Sulphone salts deriving from 2,5-dihydroxy benzene monosulphonic and 2,5-dihydroxy genzene disulphonic acids
GB1368680A (en) Adriamycin derivatives
FR2107980A1 (en) Beta-amino-penicillins - antibacterials which give high blood levels on oral administration
FR2201096A1 (en) 5-Alkoxymethyl sulphamoyl-anthranilic acid derivs - diuretics and salure-tics from corresp 5-sulphamoyl-cpds with formaldehyde and alcohols
GB1181784A (en) Sulphamic Acid Derivatives
GB1039376A (en) Process for preparing bis-hydroxyalkylsulphones and ª‰-hydroxyalkylsulphonic acid salts
FR2100844A1 (en) Amidino - (halophenyl-ureas) - used as antimalarial agents
FR2073992A5 (en) Substd oxadiazole insecticides
GB579001A (en) Manufacture of new derivatives of 4:4-diamino-diphenylsulphones
FR2128115A1 (en) Pyrid-3-ylmethyl aryloxy alkanoates - with lipotropic and coronary vasodilator activity
AT229886B (de) Verfahren zur Herstellung von Alkalisalzen der Saccharose
FR2206091A1 (en) Carbamoyloxy prostadienoic acids prepn. - for treatment of hypertension, circulatory and respiratory disorders
DK129709B (da) Fremgangsmåde til fremstilling af en alkalimetalhydroxidmodificeret form af naturlig dobbeltstrenget ribonucleinsyre.
FR2321496A1 (fr) Procede de preparation de sels de l'acide clavulanique
GB1037424A (en) Production of electrodes for alkaline storage batteries
GR27011B (el) Μεθοδος προς παραγωγην 2 - αμινο - οξαζολων.
GB1309019A (en) 1,2-disubstituted hydrazines
FR2165762A1 (en) 3-(5-mercapto-thiadiazolyl thiomethyl)-7-tetrazolylalkanamido - -3-cephem-4-carboxylic acids - useful as antibacterial agents
ZA732148B (en) Method of stabilizing dichlorocyanuric acid salts
Pusić et al. Local government in rapid social change
FR2168183A1 (en) Pyrimid-4-yl o,o-dialkyl (thio) phosphates - as biodegradable insecticides of low toxicity

Legal Events

Date Code Title Description
TP Transmission of property