FR2133503A1 - 2-(1-phenylpyrazol-4-yl)propionic acids - with antiinflammatory analgesic and antirheumatic activity - Google Patents
2-(1-phenylpyrazol-4-yl)propionic acids - with antiinflammatory analgesic and antirheumatic activityInfo
- Publication number
- FR2133503A1 FR2133503A1 FR7113296A FR7113296A FR2133503A1 FR 2133503 A1 FR2133503 A1 FR 2133503A1 FR 7113296 A FR7113296 A FR 7113296A FR 7113296 A FR7113296 A FR 7113296A FR 2133503 A1 FR2133503 A1 FR 2133503A1
- Authority
- FR
- France
- Prior art keywords
- phenylpyrazol
- propionic acids
- antiinflammatory
- cpds
- antiinflammatory analgesic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000202 analgesic effect Effects 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
- YFURHEQBISNUQG-UHFFFAOYSA-N 2-(1-phenylpyrazol-4-yl)propanoic acid Chemical class C1=C(C(C(O)=O)C)C=NN1C1=CC=CC=C1 YFURHEQBISNUQG-UHFFFAOYSA-N 0.000 title 1
- 230000003356 anti-rheumatic effect Effects 0.000 title 1
- 208000025747 Rheumatic disease Diseases 0.000 abstract 1
- 235000011054 acetic acid Nutrition 0.000 abstract 1
- 150000001243 acetic acids Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- INQOMBQAUSQDDS-UHFFFAOYSA-N iodomethane Chemical compound IC INQOMBQAUSQDDS-UHFFFAOYSA-N 0.000 abstract 1
- 238000007069 methylation reaction Methods 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003151 propanoic acid esters Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- ODZPKZBBUMBTMG-UHFFFAOYSA-N sodium amide Chemical compound [NH2-].[Na+] ODZPKZBBUMBTMG-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7113296A FR2133503A1 (en) | 1971-04-15 | 1971-04-15 | 2-(1-phenylpyrazol-4-yl)propionic acids - with antiinflammatory analgesic and antirheumatic activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7113296A FR2133503A1 (en) | 1971-04-15 | 1971-04-15 | 2-(1-phenylpyrazol-4-yl)propionic acids - with antiinflammatory analgesic and antirheumatic activity |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2133503A1 true FR2133503A1 (en) | 1972-12-01 |
FR2133503B1 FR2133503B1 (enrdf_load_stackoverflow) | 1974-08-30 |
Family
ID=9075312
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7113296A Granted FR2133503A1 (en) | 1971-04-15 | 1971-04-15 | 2-(1-phenylpyrazol-4-yl)propionic acids - with antiinflammatory analgesic and antirheumatic activity |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2133503A1 (enrdf_load_stackoverflow) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4325962A (en) * | 1969-09-12 | 1982-04-20 | Byk-Gulden Lomberg Chemische Fabrik Gmbh | Pharmaceutical compositions comprising a pyrazole derivative and method of use |
EP0299504A1 (en) * | 1987-07-17 | 1989-01-18 | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu | A process for the preparation of 1-phenyl-3-(4-chlorophenyl)-pyrazol-4-ylacetic acid and its calcium salt |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2536003C2 (de) | 1975-08-08 | 1985-11-14 | Schering AG, 1000 Berlin und 4709 Bergkamen | Pyrazol-Derivate, ihre Herstellung und diese enthaltende pharmazeutische Derivate |
-
1971
- 1971-04-15 FR FR7113296A patent/FR2133503A1/fr active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4325962A (en) * | 1969-09-12 | 1982-04-20 | Byk-Gulden Lomberg Chemische Fabrik Gmbh | Pharmaceutical compositions comprising a pyrazole derivative and method of use |
EP0299504A1 (en) * | 1987-07-17 | 1989-01-18 | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu | A process for the preparation of 1-phenyl-3-(4-chlorophenyl)-pyrazol-4-ylacetic acid and its calcium salt |
Also Published As
Publication number | Publication date |
---|---|
FR2133503B1 (enrdf_load_stackoverflow) | 1974-08-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |