FR2121447A2 - Beta-adrenergic blocking aryloxy-prop - anolamines - Google Patents

Beta-adrenergic blocking aryloxy-prop - anolamines

Info

Publication number
FR2121447A2
FR2121447A2 FR7101113A FR7101113A FR2121447A2 FR 2121447 A2 FR2121447 A2 FR 2121447A2 FR 7101113 A FR7101113 A FR 7101113A FR 7101113 A FR7101113 A FR 7101113A FR 2121447 A2 FR2121447 A2 FR 2121447A2
Authority
FR
France
Prior art keywords
beta
aryloxy
adrenergic blocking
anolamines
prop
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7101113A
Other languages
French (fr)
Other versions
FR2121447B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RECH PHARMACEUT SCIEN
Original Assignee
RECH PHARMACEUT SCIEN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RECH PHARMACEUT SCIEN filed Critical RECH PHARMACEUT SCIEN
Priority to FR7101113A priority Critical patent/FR2121447A2/en
Priority to DE19712106509 priority patent/DE2106509A1/en
Priority to GB2174571A priority patent/GB1304303A/en
Publication of FR2121447A2 publication Critical patent/FR2121447A2/en
Application granted granted Critical
Publication of FR2121447B2 publication Critical patent/FR2121447B2/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Beta-adrenergic blocking aryloxy-propanolamines Title cpds. of formula (I): (where -NR'R" is t-butylamino, isopropylamino, morpholino or dimethylaminoethyl), their opticallyl active isomers and their acid addition salts with pharmaceutically acceptable acids, some of which have no cardiodepressive effects at beta-blocking dosages and lack local-anaesthetic activity, are prepd. by reacting hydroxybenzamides with epichlorohydrin and reacting the resulting (2,3-epoxy-propoxy)-benzamides with HNR'R".
FR7101113A 1970-02-13 1971-01-14 Beta-adrenergic blocking aryloxy-prop - anolamines Granted FR2121447A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR7101113A FR2121447A2 (en) 1971-01-14 1971-01-14 Beta-adrenergic blocking aryloxy-prop - anolamines
DE19712106509 DE2106509A1 (en) 1970-02-13 1971-02-11 Aryloxy propanolamine
GB2174571A GB1304303A (en) 1970-02-13 1971-04-19

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7101113A FR2121447A2 (en) 1971-01-14 1971-01-14 Beta-adrenergic blocking aryloxy-prop - anolamines

Publications (2)

Publication Number Publication Date
FR2121447A2 true FR2121447A2 (en) 1972-08-25
FR2121447B2 FR2121447B2 (en) 1974-04-12

Family

ID=9070266

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7101113A Granted FR2121447A2 (en) 1970-02-13 1971-01-14 Beta-adrenergic blocking aryloxy-prop - anolamines

Country Status (1)

Country Link
FR (1) FR2121447A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1236523B (en) * 1962-02-15 1967-03-16 Sanol Arznei Schwarz Gmbh Process for the preparation of basic phenyl and naphthyl ethers and thioethers and their salts

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1236523B (en) * 1962-02-15 1967-03-16 Sanol Arznei Schwarz Gmbh Process for the preparation of basic phenyl and naphthyl ethers and thioethers and their salts

Also Published As

Publication number Publication date
FR2121447B2 (en) 1974-04-12

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