FR2117750A1 - 10-(3-quinuclidinylmethyl)phenothiazine 5-oxide and 5,5 - -dioxide - with antihistamine,antidepressant and tranquillizing activ - Google Patents
10-(3-quinuclidinylmethyl)phenothiazine 5-oxide and 5,5 - -dioxide - with antihistamine,antidepressant and tranquillizing activInfo
- Publication number
- FR2117750A1 FR2117750A1 FR7045116A FR7045116A FR2117750A1 FR 2117750 A1 FR2117750 A1 FR 2117750A1 FR 7045116 A FR7045116 A FR 7045116A FR 7045116 A FR7045116 A FR 7045116A FR 2117750 A1 FR2117750 A1 FR 2117750A1
- Authority
- FR
- France
- Prior art keywords
- antihistamine
- phenothiazine
- quinuclidinylmethyl
- tranquillizing
- activ
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 title abstract 2
- 230000001387 anti-histamine Effects 0.000 title abstract 2
- 239000000935 antidepressant agent Substances 0.000 title abstract 2
- 239000000739 antihistaminic agent Substances 0.000 title abstract 2
- GWHIBUGIPBSCCU-UHFFFAOYSA-N 10-(1-azabicyclo[2.2.2]octan-3-ylmethyl)phenothiazine 5-oxide Chemical compound C12=CC=CC=C2S(=O)C2=CC=CC=C2N1CC1C(CC2)CCN2C1 GWHIBUGIPBSCCU-UHFFFAOYSA-N 0.000 title 1
- ZAYUOSICZWFJSW-UHFFFAOYSA-N 10h-phenothiazine 5,5-dioxide Chemical compound C1=CC=C2S(=O)(=O)C3=CC=CC=C3NC2=C1 ZAYUOSICZWFJSW-UHFFFAOYSA-N 0.000 title 1
- 230000001430 anti-depressive effect Effects 0.000 title 1
- 229940005513 antidepressants Drugs 0.000 title 1
- 230000002936 tranquilizing effect Effects 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- JQWHASGSAFIOCM-UHFFFAOYSA-M sodium periodate Chemical compound [Na+].[O-]I(=O)(=O)=O JQWHASGSAFIOCM-UHFFFAOYSA-M 0.000 abstract 2
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical compound C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 abstract 1
- ATTZFSUZZUNHBP-UHFFFAOYSA-N Piperonyl sulfoxide Chemical compound CCCCCCCCS(=O)C(C)CC1=CC=C2OCOC2=C1 ATTZFSUZZUNHBP-UHFFFAOYSA-N 0.000 abstract 1
- 239000007800 oxidant agent Substances 0.000 abstract 1
- 150000002978 peroxides Chemical class 0.000 abstract 1
- 229950000688 phenothiazine Drugs 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- 125000001174 sulfone group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7045116A FR2117750A1 (en) | 1970-12-15 | 1970-12-15 | 10-(3-quinuclidinylmethyl)phenothiazine 5-oxide and 5,5 - -dioxide - with antihistamine,antidepressant and tranquillizing activ |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7045116A FR2117750A1 (en) | 1970-12-15 | 1970-12-15 | 10-(3-quinuclidinylmethyl)phenothiazine 5-oxide and 5,5 - -dioxide - with antihistamine,antidepressant and tranquillizing activ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2117750A1 true FR2117750A1 (en) | 1972-07-28 |
| FR2117750B1 FR2117750B1 (OSRAM) | 1974-04-12 |
Family
ID=9065792
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7045116A Granted FR2117750A1 (en) | 1970-12-15 | 1970-12-15 | 10-(3-quinuclidinylmethyl)phenothiazine 5-oxide and 5,5 - -dioxide - with antihistamine,antidepressant and tranquillizing activ |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2117750A1 (OSRAM) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7003014A (OSRAM) * | 1969-03-03 | 1970-09-07 |
-
1970
- 1970-12-15 FR FR7045116A patent/FR2117750A1/fr active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7003014A (OSRAM) * | 1969-03-03 | 1970-09-07 |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2117750B1 (OSRAM) | 1974-04-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |