FR2112142A1 - 1,2-diphenylcyclopropanes and chalcone intermediates - - with neuroleptic,tranquillizing,antiemetic activity - Google Patents

1,2-diphenylcyclopropanes and chalcone intermediates - - with neuroleptic,tranquillizing,antiemetic activity

Info

Publication number
FR2112142A1
FR2112142A1 FR7040149A FR7040149A FR2112142A1 FR 2112142 A1 FR2112142 A1 FR 2112142A1 FR 7040149 A FR7040149 A FR 7040149A FR 7040149 A FR7040149 A FR 7040149A FR 2112142 A1 FR2112142 A1 FR 2112142A1
Authority
FR
France
Prior art keywords
diphenylcyclopropanes
tranquillizing
neuroleptic
methoxychalcone
antiemetic activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7040149A
Other languages
French (fr)
Other versions
FR2112142B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR7040149A priority Critical patent/FR2112142A1/en
Publication of FR2112142A1 publication Critical patent/FR2112142A1/en
Application granted granted Critical
Publication of FR2112142B1 publication Critical patent/FR2112142B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Abstract

Cpds. are of formula: (where R1, R2 = OH, SH, 1-4C alkoxy except when R1=R2=OMe, 3-5C alkenyloxy, 3-5C alkynyloxy, 1-4C alkylthio, 3-5C alkenylthio, alkoxycarbonyl, dialkylaminoalkoxy and its acid-addn. and quaternary ammonium salts; R3, R4=H, halogen, 1-4C alkyl or 1-4C alkoxy) and the inters. are 31-hydroxy-4-methoxychalcone, 4-hydroxy-21-methoxychalcone, 4-beta-dimethylaminoethoxy-21-methoxychalcone, 41-chloro-21-beta-dimethylaminoethoxy-4-methoxychalcone.
FR7040149A 1970-11-09 1970-11-09 1,2-diphenylcyclopropanes and chalcone intermediates - - with neuroleptic,tranquillizing,antiemetic activity Granted FR2112142A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7040149A FR2112142A1 (en) 1970-11-09 1970-11-09 1,2-diphenylcyclopropanes and chalcone intermediates - - with neuroleptic,tranquillizing,antiemetic activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7040149A FR2112142A1 (en) 1970-11-09 1970-11-09 1,2-diphenylcyclopropanes and chalcone intermediates - - with neuroleptic,tranquillizing,antiemetic activity

Publications (2)

Publication Number Publication Date
FR2112142A1 true FR2112142A1 (en) 1972-06-16
FR2112142B1 FR2112142B1 (en) 1974-08-30

Family

ID=9063931

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7040149A Granted FR2112142A1 (en) 1970-11-09 1970-11-09 1,2-diphenylcyclopropanes and chalcone intermediates - - with neuroleptic,tranquillizing,antiemetic activity

Country Status (1)

Country Link
FR (1) FR2112142A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103130742A (en) * 2013-02-27 2013-06-05 陕西科技大学 N-phenothiazinylchalcone preparation method
CN114105753A (en) * 2021-09-17 2022-03-01 温州医科大学 Fisetin derivative and application thereof in preparation of anti-inflammatory drugs

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103130742A (en) * 2013-02-27 2013-06-05 陕西科技大学 N-phenothiazinylchalcone preparation method
CN114105753A (en) * 2021-09-17 2022-03-01 温州医科大学 Fisetin derivative and application thereof in preparation of anti-inflammatory drugs
CN114105753B (en) * 2021-09-17 2024-02-20 温州医科大学 Fisetin derivative and application thereof in preparation of anti-inflammatory drugs

Also Published As

Publication number Publication date
FR2112142B1 (en) 1974-08-30

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