FR2108456A5 - Antibacterial azetidin-2-ones - prepd from related sulphonoxy cpds and nucleophiles - Google Patents
Antibacterial azetidin-2-ones - prepd from related sulphonoxy cpds and nucleophilesInfo
- Publication number
- FR2108456A5 FR2108456A5 FR7134243A FR7134243A FR2108456A5 FR 2108456 A5 FR2108456 A5 FR 2108456A5 FR 7134243 A FR7134243 A FR 7134243A FR 7134243 A FR7134243 A FR 7134243A FR 2108456 A5 FR2108456 A5 FR 2108456A5
- Authority
- FR
- France
- Prior art keywords
- alkyl
- opt
- substd
- alkoxy
- benzyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- MNFORVFSTILPAW-UHFFFAOYSA-N azetidin-2-one Chemical class O=C1CCN1 MNFORVFSTILPAW-UHFFFAOYSA-N 0.000 title 1
- 239000012038 nucleophile Substances 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- -1 sulphamoyl Chemical group 0.000 abstract 4
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 3
- 229910052794 bromium Inorganic materials 0.000 abstract 3
- 229910052801 chlorine Inorganic materials 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- 125000003282 alkyl amino group Chemical group 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- 125000000304 alkynyl group Chemical group 0.000 abstract 2
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 2
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical group C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 125000004428 fluoroalkoxy group Chemical group 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000005035 acylthio group Chemical group 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000005108 alkenylthio group Chemical group 0.000 abstract 1
- 125000005078 alkoxycarbonylalkyl group Chemical group 0.000 abstract 1
- 125000005093 alkyl carbonyl alkyl group Chemical group 0.000 abstract 1
- 125000005109 alkynylthio group Chemical group 0.000 abstract 1
- 125000005097 aminocarbonylalkyl group Chemical group 0.000 abstract 1
- 239000000010 aprotic solvent Substances 0.000 abstract 1
- 125000005110 aryl thio group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000004966 cyanoalkyl group Chemical group 0.000 abstract 1
- 125000004967 formylalkyl group Chemical group 0.000 abstract 1
- 125000000262 haloalkenyl group Chemical group 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
- C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19702046822 DE2046822A1 (de) | 1970-09-23 | 1970-09-23 | Neue Azetidinone-(2) und Verfahren zu deren Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2108456A5 true FR2108456A5 (en) | 1972-05-19 |
Family
ID=5783147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7134243A Expired FR2108456A5 (en) | 1970-09-23 | 1971-09-23 | Antibacterial azetidin-2-ones - prepd from related sulphonoxy cpds and nucleophiles |
Country Status (5)
| Country | Link |
|---|---|
| AT (1) | AT313912B (enExample) |
| BE (1) | BE772990A (enExample) |
| DE (1) | DE2046822A1 (enExample) |
| FR (1) | FR2108456A5 (enExample) |
| NL (1) | NL7112824A (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4162250A (en) * | 1976-09-08 | 1979-07-24 | Smithkline Corporation | 3-Aminoazetidinone derivatives |
| JPS56125360A (en) * | 1980-03-07 | 1981-10-01 | Sagami Chem Res Center | Beta-lactam compound |
| US5229510A (en) * | 1983-12-01 | 1993-07-20 | Merck & Co., Inc. | β-lactams useful in determining the amount of elastase in a clinical sample |
| US4680391A (en) * | 1983-12-01 | 1987-07-14 | Merck & Co., Inc. | Substituted azetidinones as anti-inflammatory and antidegenerative agents |
| US5229381A (en) * | 1983-12-01 | 1993-07-20 | Merck & Co., Inc. | Substituted azetidinones as anti-inflammatory and antidegenerative agents |
| US5100880A (en) * | 1991-03-20 | 1992-03-31 | Merck & Co., Inc. | Novel betalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone |
| US5104862A (en) * | 1991-03-20 | 1992-04-14 | Merck & Co., Inc. | Bethalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone |
| US5348953A (en) * | 1991-06-25 | 1994-09-20 | Merck & Co., Inc. | Substituted azetidinones as anti-inflammatory and antidegenerative agents |
| CA2147129A1 (en) * | 1992-10-27 | 1994-05-11 | James B. Doherty | New substituted azetidinones as anti-inflammatory and antidegenerative agents |
| US5591737A (en) * | 1992-12-17 | 1997-01-07 | Merck & Co., Inc. | Substituted azetidinones as anti-inflammatory and antidegenerative agents |
| US5747485A (en) * | 1995-04-13 | 1998-05-05 | Merck & Co., Inc. | Substituted azetidiones as anti-inflammatory and antidegenerative agents |
-
1970
- 1970-09-23 DE DE19702046822 patent/DE2046822A1/de active Pending
-
1971
- 1971-09-17 NL NL7112824A patent/NL7112824A/xx unknown
- 1971-09-22 AT AT821771A patent/AT313912B/de not_active IP Right Cessation
- 1971-09-23 FR FR7134243A patent/FR2108456A5/fr not_active Expired
- 1971-09-23 BE BE772990A patent/BE772990A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL7112824A (enExample) | 1972-03-27 |
| BE772990A (fr) | 1972-03-23 |
| AT313912B (de) | 1974-03-11 |
| DE2046822A1 (de) | 1972-03-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FR2108456A5 (en) | Antibacterial azetidin-2-ones - prepd from related sulphonoxy cpds and nucleophiles | |
| ATE25196T1 (de) | Stabilisierung von 1-substituierten imidazolderivaten in talk. | |
| GB1240281A (en) | Imidazolyl compounds and process | |
| FR2108457A5 (en) | Antibacterial azetidin-2-one derivs - prepd by ozonolysis of other derivs contg unsatd gps | |
| GB1412886A (en) | Penicillin and cephalosporin compounds | |
| FR2337554A1 (fr) | Nouveaux derives de la pyrazolidinedione | |
| SE8305009D0 (sv) | Sett att framstella antibakteriella amidforeningar | |
| FR2001284A1 (en) | Penicillin derivatives - antibiotics, especially for veterinary use | |
| ES463737A1 (es) | Metodo para producir cefalosporinas y similares | |
| US4505894A (en) | Therapeutic compounds containing β-lactams | |
| ES420869A1 (es) | Un procedimiento para la preparacion de alfa-aminoacilcefa-losporinas. | |
| ES371709A1 (es) | Un metodo para producir una penicilina sintetica. | |
| FR2108458A5 (en) | Antibacterial azetidin-2-ones - from schiff bases and substd-acetyl halides | |
| ES8100278A1 (es) | Un procedimiento para la preparacion de derivados de 5-triazina | |
| IT1046792B (it) | Triazol derivati alogenati sul l eterociclico processi per la loro produzione e loro impiego come fungicidi | |
| FR2170496A5 (en) | 7-Acylamino-3-substd.-3-cephem-4-carboxylic acids prepn. - from corresp. 7-(5-acylaminoadipamido) derivs | |
| GB1325846A (en) | Process for the preparation of a 3-thiomethyl cephalosporin | |
| GB1421280A (en) | 3-heterocyclicthiomethylcephalosporins | |
| ES389076A1 (es) | Un metodo para la preparacion de 6-(d-alfa-amino -p- hidro-xifenilacetamido) penicilanato sodico o potasico. | |
| IE34651L (en) | Heterocyclic compounds. | |
| GB1138745A (en) | Penicillins | |
| FR2336130A1 (fr) | Composes utilisables dans le traitement des infections bacteriennes | |
| IE37420B1 (en) | Derivatives of penam-3-carboxylic acid and cephem-4-carboxylic acid and processes for their manufacture | |
| FR2127807A5 (en) | 2-fluoroacetylamino-benzothiazoles - insecticides, acaricides and nematocides | |
| SE7702558L (sv) | Forfarande for framstellning av cefalosporiner |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |