FR2105090A2 - Metabenzoyl-phenylacetic acid esters, ana-lg - Google Patents

Metabenzoyl-phenylacetic acid esters, ana-lg

Info

Publication number
FR2105090A2
FR2105090A2 FR7034591A FR7034591A FR2105090A2 FR 2105090 A2 FR2105090 A2 FR 2105090A2 FR 7034591 A FR7034591 A FR 7034591A FR 7034591 A FR7034591 A FR 7034591A FR 2105090 A2 FR2105090 A2 FR 2105090A2
Authority
FR
France
Prior art keywords
metabenzoyl
acid esters
phenylacetic acid
ana
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7034591A
Other languages
French (fr)
Other versions
FR2105090B2 (en
Inventor
A Allais
J Meier
J Dube
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7034591A priority Critical patent/FR2105090A2/en
Priority to IL36521A priority patent/IL36521A/en
Priority to US00133429A priority patent/US3741988A/en
Priority to CH534071A priority patent/CH542840A/en
Priority to NL7104960A priority patent/NL7104960A/xx
Priority to CA110,363*7A priority patent/CA947306A/en
Priority to CH1095573A priority patent/CH567014A5/xx
Priority to AT316371A priority patent/AT310147B/en
Priority to SE7104861A priority patent/SE377331B/xx
Priority to CH331872A priority patent/CH539035A/en
Priority to DK178171AA priority patent/DK127973B/en
Priority to BE765764A priority patent/BE765764A/en
Priority to DE19712118365 priority patent/DE2118365C3/en
Priority to JP2353171A priority patent/JPS5547026B1/ja
Priority to GB992371*[A priority patent/GB1324622A/en
Priority to ES395314A priority patent/ES395314A2/en
Publication of FR2105090A2 publication Critical patent/FR2105090A2/en
Priority to US00346770A priority patent/US3829585A/en
Application granted granted Critical
Publication of FR2105090B2 publication Critical patent/FR2105090B2/fr
Priority to JP2146279A priority patent/JPS54145644A/en
Priority to US06/015,786 priority patent/US4192890A/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polyesters Or Polycarbonates (AREA)

Abstract

Metabenzoyl-phenylacetic acid esters anagestics, antiinflammatories The new cpds. are of formula in which R1 is H or lower alkyl, R2 and R3 are H or together represent where P and Q are 1-5C alkyl, and the two benzene rings may be substd. by one or more Cl, F, Br, alkyl, alkyloxy, alkylthio or CF3 radicals. They have high antiinflammatory and analgesic activity, with low ulcerogenic properties.
FR7034591A 1970-04-15 1970-09-24 Metabenzoyl-phenylacetic acid esters, ana-lg Granted FR2105090A2 (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
FR7034591A FR2105090A2 (en) 1970-09-24 1970-09-24 Metabenzoyl-phenylacetic acid esters, ana-lg
IL36521A IL36521A (en) 1970-04-15 1971-03-31 M-benzoylphenylacetic acid esters and process of preparation
US00133429A US3741988A (en) 1970-04-15 1971-04-12 Novel benzoylphenylacetic acid esters
NL7104960A NL7104960A (en) 1970-04-15 1971-04-14
CA110,363*7A CA947306A (en) 1970-04-15 1971-04-14 Procede de preparation de nouveaux esters de l'acide metabenzoylphenylacetique
CH1095573A CH567014A5 (en) 1970-04-15 1971-04-14
AT316371A AT310147B (en) 1970-04-15 1971-04-14 Process for the preparation of new m-benzoylphenylalkanoic acid esters
SE7104861A SE377331B (en) 1970-04-15 1971-04-14
CH331872A CH539035A (en) 1970-04-15 1971-04-14 Metabenzoyl-phenylacetic acid esters, ana-lg
CH534071A CH542840A (en) 1970-04-15 1971-04-14 Process for the preparation of new esters of metabenzoylphenylacetic acid
DK178171AA DK127973B (en) 1970-04-15 1971-04-15 Analogous process for the preparation of 2,3-substituted 1-propyl esters of m-benzoylphenylacetic acids.
BE765764A BE765764A (en) 1970-04-15 1971-04-15 NEW ESTERS OF METABENZOYLPHENYLACETIC ACID AND METHOD OF PREPARATION
DE19712118365 DE2118365C3 (en) 1970-04-15 1971-04-15 m-Benzoylphenylacetic acid esters, processes for their preparation and pharmaceutical compositions
JP2353171A JPS5547026B1 (en) 1970-04-15 1971-04-15
GB992371*[A GB1324622A (en) 1970-04-15 1971-04-19 Substituted phenylacetic acid esters processes for their preparation and compositions incorporating them
ES395314A ES395314A2 (en) 1970-09-24 1971-09-22 Procedure for preparation of new sters of meta-benzoilphenilactic acid. (Machine-translation by Google Translate, not legally binding)
US00346770A US3829585A (en) 1970-04-15 1973-04-02 Novel benzoylphenylacetic acid esters in the treatment of pain and inflammation
JP2146279A JPS54145644A (en) 1970-04-15 1979-02-27 Manufacture of novel mmbenzoylphenylacetic acid
US06/015,786 US4192890A (en) 1970-04-15 1979-02-28 Novel benzoylphenylacetic acid esters

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7034591A FR2105090A2 (en) 1970-09-24 1970-09-24 Metabenzoyl-phenylacetic acid esters, ana-lg

Publications (2)

Publication Number Publication Date
FR2105090A2 true FR2105090A2 (en) 1972-04-28
FR2105090B2 FR2105090B2 (en) 1974-03-22

Family

ID=9061783

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7034591A Granted FR2105090A2 (en) 1970-04-15 1970-09-24 Metabenzoyl-phenylacetic acid esters, ana-lg

Country Status (2)

Country Link
ES (1) ES395314A2 (en)
FR (1) FR2105090A2 (en)

Also Published As

Publication number Publication date
FR2105090B2 (en) 1974-03-22
ES395314A2 (en) 1973-12-16

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