FR20C1036I2 - PERIVASCULAR MESENCHYMAL PRECURSOR CELLS - Google Patents
PERIVASCULAR MESENCHYMAL PRECURSOR CELLSInfo
- Publication number
- FR20C1036I2 FR20C1036I2 FR20C1036C FR20C1036C FR20C1036I2 FR 20C1036 I2 FR20C1036 I2 FR 20C1036I2 FR 20C1036 C FR20C1036 C FR 20C1036C FR 20C1036 C FR20C1036 C FR 20C1036C FR 20C1036 I2 FR20C1036 I2 FR 20C1036I2
- Authority
- FR
- France
- Prior art keywords
- precursor cells
- mesenchymal precursor
- perivascular mesenchymal
- perivascular
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 210000002901 mesenchymal stem cell Anatomy 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0668—Mesenchymal stem cells from other natural sources
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
- C12N5/0691—Vascular smooth muscle cells; 3D culture thereof, e.g. models of blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/42—Organic phosphate, e.g. beta glycerophosphate
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/135—Platelet-derived growth factor [PDGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/165—Vascular endothelial growth factor [VEGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/235—Leukemia inhibitory factor [LIF]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
- C12N2506/1392—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from mesenchymal stem cells from other natural sources
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Virology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2003901668A AU2003901668A0 (en) | 2003-03-28 | 2003-03-28 | Non-haemopoietic precursor cells |
| EP04723935A EP1613741A4 (en) | 2003-03-28 | 2004-03-29 | Perivascular mesenchymal precursor cells |
| PCT/AU2004/000416 WO2004085630A1 (en) | 2003-03-28 | 2004-03-29 | Perivascular mesenchymal precursor cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR20C1036I1 FR20C1036I1 (en) | 2020-02-10 |
| FR20C1036I2 true FR20C1036I2 (en) | 2022-11-18 |
Family
ID=31500707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR20C1036C Active FR20C1036I2 (en) | 2003-03-28 | 2020-08-06 | PERIVASCULAR MESENCHYMAL PRECURSOR CELLS |
Country Status (14)
| Country | Link |
|---|---|
| US (6) | US7947266B2 (en) |
| EP (4) | EP2380971B1 (en) |
| JP (10) | JP5721302B2 (en) |
| CN (4) | CN1809632B (en) |
| AU (7) | AU2003901668A0 (en) |
| CA (4) | CA2520273C (en) |
| DK (1) | DK1613335T3 (en) |
| ES (3) | ES2465226T3 (en) |
| FR (1) | FR20C1036I2 (en) |
| NL (1) | NL301059I2 (en) |
| PL (1) | PL1613335T3 (en) |
| PT (1) | PT1613335E (en) |
| SI (1) | SI1613335T1 (en) |
| WO (2) | WO2004084921A1 (en) |
Families Citing this family (106)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7514074B2 (en) | 1997-07-14 | 2009-04-07 | Osiris Therapeutics, Inc. | Cardiac muscle regeneration using mesenchymal stem cells |
| US8062675B2 (en) * | 1999-07-07 | 2011-11-22 | Angioblast Systems, Inc. | Mesenchymal precursor cell |
| US7670628B2 (en) * | 1999-07-07 | 2010-03-02 | Angioblast Systems, Inc. | Mesenchymal precursor cell |
| AUPQ147799A0 (en) * | 1999-07-07 | 1999-07-29 | Medvet Science Pty. Ltd. | Mesenchymal precursor cell |
| US20050158289A1 (en) * | 1999-07-07 | 2005-07-21 | Simmons Paul J. | Mesenchymal precursor cell and use thereof in the repair of bone defects and fractures in mammals |
| AU2003901668A0 (en) * | 2003-03-28 | 2003-05-01 | Medvet Science Pty. Ltd. | Non-haemopoietic precursor cells |
| AU2004210891B2 (en) | 2003-02-11 | 2008-09-25 | Dolores Baksh | Progenitor cells from Wharton's jelly of human umbilical cord |
| JP5265190B2 (en) * | 2004-09-24 | 2013-08-14 | メソブラスト,インコーポレーテッド | Pluripotent proliferating mesenchymal progenitor progeny (MEMP) and uses thereof |
| ES2645012T3 (en) | 2004-09-24 | 2017-12-01 | Mesoblast, Inc. | Method to enhance the proliferation and / or survival of mesenchymal precursor cells (MPC) |
| EP2048227B1 (en) | 2005-02-11 | 2015-08-19 | Agency For Science, Technology And Research | Methods for proliferating stem cells |
| US8287853B2 (en) | 2005-02-11 | 2012-10-16 | Agency For Science, Technology And Research | Methods of culturing mesenchymal stem cells |
| CA2604493C (en) | 2005-04-12 | 2015-12-22 | Angioblast Systems, Inc. | Isolation of adult multipotential cells by tissue non-specific alkaline phosphatase |
| US20080213235A1 (en) * | 2005-07-29 | 2008-09-04 | University Of Virginia Patent Foundation | Adipose Tissue Stem Cells, Perivascular Cells and Pericytes |
| EP1780265A1 (en) * | 2005-10-25 | 2007-05-02 | Stiftung CAESAR | Differentiation of stem cells into chondrocytes |
| CN101479377A (en) * | 2005-12-22 | 2009-07-08 | 简·恩尼斯 | Viable cells from frozen umbilical cord tissue |
| CA2649874C (en) * | 2006-05-05 | 2015-01-27 | John E. Davies | Immune privileged and modulatory progenitor cells |
| AU2007272313B2 (en) * | 2006-07-12 | 2013-11-21 | Mesoblast, Inc. | Treatment of excessive neovascularization |
| FR2909559B1 (en) * | 2006-12-06 | 2012-09-07 | Inst Vaisseaux Et Du Sang | CELLULAR PREPARATIONS FOR USE AS AGENT STIMULATING REVASCULARIZATION |
| US20100040584A1 (en) * | 2006-12-19 | 2010-02-18 | Children's Medical Center Corporation | Methods for promoting neovascularization |
| CA2679178A1 (en) * | 2007-02-26 | 2008-09-04 | Mount Sinai Hospital | Compositions and methods for treating peripheral vascular diseases |
| KR102099285B1 (en) | 2007-08-06 | 2020-04-10 | 메소블라스트, 아이엔씨. | Methods of generating, repairing and/or maintaining connective tissue in vivo |
| US9005599B2 (en) | 2008-04-21 | 2015-04-14 | Tissue Regeneration Therapeutics Inc. | Genetically modified human umbilical cord perivascular cells for prophylaxis against or treatment of biological or chemical agents |
| TR201815802T4 (en) | 2008-06-25 | 2018-11-21 | Mesoblast Inc | Repair and / or reconstruction of invertabral discs. |
| KR20110036101A (en) * | 2008-06-30 | 2011-04-06 | 안지오블라스트 시스템스 인코퍼레이티드 | Treatment of Ocular Diseases and Excessive Angiogenesis with Combination Therapy |
| WO2010011185A1 (en) * | 2008-07-21 | 2010-01-28 | Agency For Science, Technology And Research | Stem cells obtained through in vitro culture with heparan sulfate |
| DK2330889T3 (en) | 2008-08-20 | 2017-01-30 | Anthrogenesis Corp | Improved cell composition and process for making the same |
| MX2008014536A (en) * | 2008-11-13 | 2009-01-16 | Internac Para La Terapia Celul | Cellular regenerator compound. |
| CN104546912B (en) * | 2008-11-20 | 2019-11-08 | 中胚有限公司 | Methods for treating pancreatic dysfunction |
| EP2408904B1 (en) | 2009-03-20 | 2017-10-18 | Mesoblast, Inc. | Production of reprogrammed pluripotent cells |
| WO2011022071A2 (en) | 2009-08-20 | 2011-02-24 | The Regents Of The University Of California | Cardiac compositions |
| US8628979B2 (en) | 2009-10-21 | 2014-01-14 | Pronota N.V. | MCAM as a biomarker for fluid homeostasis |
| US9308277B2 (en) | 2010-02-25 | 2016-04-12 | Mesoblast International Sàrl | Protease-resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
| US10130736B1 (en) | 2010-05-14 | 2018-11-20 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US9352003B1 (en) | 2010-05-14 | 2016-05-31 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US8883210B1 (en) | 2010-05-14 | 2014-11-11 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| CA2803639C (en) | 2010-07-02 | 2019-01-08 | Mesoblast, Inc. | Method of treating graft versus host disease |
| EP2606121B1 (en) * | 2010-08-19 | 2016-05-11 | The Regents of The University of California | Compositions comrpising perivascular stem cells and nell-1 protein |
| CN101985052B (en) * | 2010-08-31 | 2013-11-06 | 中国人民解放军第二军医大学 | Skin substitute for automatically capturing endothelial progenitor cells and promoting vascularization and construction method thereof |
| WO2012040408A2 (en) * | 2010-09-23 | 2012-03-29 | Children's Medical Center Corporation | Engineered vascular adipose tissue |
| EP2625263B1 (en) | 2010-10-08 | 2020-03-11 | Terumo BCT, Inc. | Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system |
| WO2012048093A2 (en) | 2010-10-08 | 2012-04-12 | Osiris Therapeutics, Inc. | Enhanced msc preparations |
| US8834928B1 (en) | 2011-05-16 | 2014-09-16 | Musculoskeletal Transplant Foundation | Tissue-derived tissugenic implants, and methods of fabricating and using same |
| JP6091492B2 (en) * | 2011-05-19 | 2017-03-08 | メゾブラスト,インコーポレーテッド | Methods for treating obesity and / or metabolic syndrome |
| SG195127A1 (en) * | 2011-06-03 | 2013-12-30 | Mesoblast Inc | Methods of treating or preventing neurological diseases |
| CA2837898C (en) * | 2011-06-03 | 2020-06-30 | Mesoblast, Inc. | Method of treating the effects of stroke |
| WO2012170495A1 (en) | 2011-06-07 | 2012-12-13 | Provasculon, Inc. | Methods for repairing tissue damage using protease-resistant mutants of stromal cell derived factor-1 |
| CA2839341C (en) | 2011-07-04 | 2020-12-15 | Mesoblast, Inc. | Methods of treating or preventing rheumatic disease |
| AU2012279995C1 (en) | 2011-07-06 | 2019-10-24 | Cell Therapy Limited | Progenitor cells of mesodermal lineage |
| EP2734618B1 (en) * | 2011-07-20 | 2017-06-14 | Paracelsus Medizinische Privatuniversität Salzburg - Privatstiftung | Pluripotent tendon and ligament perivascular cells |
| EP2751256A4 (en) * | 2011-08-29 | 2015-01-28 | Safeguard Cell Technology Inc | Isolating and therapeutic use of perivascular medicinal cells |
| JP5831059B2 (en) * | 2011-09-07 | 2015-12-09 | ソニー株式会社 | Optical measuring apparatus, flow cytometer, and optical measuring method |
| US9177336B2 (en) * | 2011-09-08 | 2015-11-03 | Telefonaktiebolaget L M Ericsson (Publ) | Apparatuses and methods for recommending a path through an information space |
| AU2012307086B2 (en) | 2011-09-09 | 2016-05-26 | Mesoblast, Inc. | Methods for increasing osteoblastic function |
| CN102539736B (en) * | 2011-12-16 | 2015-04-29 | 北京汉氏联合生物技术有限公司 | CD106-positive cells, and identification and preparation method and application thereof |
| JP6901823B2 (en) | 2012-08-01 | 2021-07-14 | ユナイテッド セラピューティクス コーポレイション | Treatment of pulmonary arterial hypertension with mesenchymal stem cells |
| ES2869701T3 (en) | 2012-08-01 | 2021-10-25 | United Therapeutics Corp | Treatment of pulmonary arterial hypertension with prostacyclin-treated endothelial progenitor cells |
| KR102217962B1 (en) * | 2012-12-12 | 2021-02-22 | 메소블라스트, 아이엔씨. | Treatment of diseases of endothelial dysfunction and inflammation |
| CA2893951C (en) * | 2012-12-12 | 2022-05-03 | Mesoblast, Inc. | Methods of treating or preventing respiratory conditions |
| EP2943069B1 (en) | 2013-01-09 | 2018-08-15 | United Therapeutics Corporation | Treatment of vasculopathy with prostacyclin and mesenchymal stem cells |
| WO2015017500A1 (en) | 2013-07-30 | 2015-02-05 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
| WO2015073913A1 (en) | 2013-11-16 | 2015-05-21 | Terumo Bct, Inc. | Expanding cells in a bioreactor |
| CN106029086A (en) * | 2013-12-13 | 2016-10-12 | 美索布拉斯特国际有限公司 | Methods for repairing tissue damage using protease-resistant mutants of stromal cell derived factor-1 |
| CN106232800B (en) | 2014-03-25 | 2020-07-03 | 泰尔茂比司特公司 | Passive replacement of media |
| SG11201607925SA (en) * | 2014-04-07 | 2016-10-28 | Mesoblast Internat Sarl | Improved stem cell composition |
| WO2015157694A1 (en) | 2014-04-11 | 2015-10-15 | The Administrators Of The Tulane Educational Fund | Cell-surface marker of early msc aging |
| WO2015189063A1 (en) | 2014-06-10 | 2015-12-17 | Mesoblast International Sàrl | Treatment of immune disorders |
| KR102263824B1 (en) * | 2014-07-11 | 2021-06-10 | 가부시키가이샤 메토세라 | Cardiac cell culture material |
| JP6830059B2 (en) | 2014-09-26 | 2021-02-17 | テルモ ビーシーティー、インコーポレーテッド | Scheduled cell feeding |
| ES2956655T3 (en) | 2014-12-23 | 2023-12-26 | Mesoblast Int Sarl | Method for the treatment of heart failure |
| CA2971514A1 (en) | 2014-12-23 | 2016-06-30 | Mesoblast International Sarl | Prevention of progressive heart failure |
| CN113957043A (en) | 2015-03-04 | 2022-01-21 | 迈索布拉斯特国际有限公司 | Cell culture method of mesenchymal stem cells |
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