FR2097038A1 - 1-(substd phenyl)-2-oxo-4-piperazinocarbonyl pyrrolidines - analgesic - Google Patents

1-(substd phenyl)-2-oxo-4-piperazinocarbonyl pyrrolidines - analgesic

Info

Publication number
FR2097038A1
FR2097038A1 FR7028026A FR7028026A FR2097038A1 FR 2097038 A1 FR2097038 A1 FR 2097038A1 FR 7028026 A FR7028026 A FR 7028026A FR 7028026 A FR7028026 A FR 7028026A FR 2097038 A1 FR2097038 A1 FR 2097038A1
Authority
FR
France
Prior art keywords
piperazinocarbonyl
pyrrolidines
analgesic
oxo
substd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7028026A
Other languages
French (fr)
Other versions
FR2097038B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Roger Bellon SA
Original Assignee
Laboratoire Roger Bellon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Roger Bellon SA filed Critical Laboratoire Roger Bellon SA
Priority to FR7028026A priority Critical patent/FR2097038A1/en
Publication of FR2097038A1 publication Critical patent/FR2097038A1/en
Application granted granted Critical
Publication of FR2097038B1 publication Critical patent/FR2097038B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel compds. are of formula (I) (where R is H, lower alkyl or an aryl ring, opt. substd. by alkyl, alkoxy or methylenedioxy, R1, R2 are H, lower alkyl, opt. halo substd. or lower alkoxy; or R1 and R2 together are methylenedioxy, cis and trans isomers and non-toxic salts thereof).
FR7028026A 1970-07-29 1970-07-29 1-(substd phenyl)-2-oxo-4-piperazinocarbonyl pyrrolidines - analgesic Granted FR2097038A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7028026A FR2097038A1 (en) 1970-07-29 1970-07-29 1-(substd phenyl)-2-oxo-4-piperazinocarbonyl pyrrolidines - analgesic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7028026A FR2097038A1 (en) 1970-07-29 1970-07-29 1-(substd phenyl)-2-oxo-4-piperazinocarbonyl pyrrolidines - analgesic

Publications (2)

Publication Number Publication Date
FR2097038A1 true FR2097038A1 (en) 1972-03-03
FR2097038B1 FR2097038B1 (en) 1974-04-12

Family

ID=9059451

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7028026A Granted FR2097038A1 (en) 1970-07-29 1970-07-29 1-(substd phenyl)-2-oxo-4-piperazinocarbonyl pyrrolidines - analgesic

Country Status (1)

Country Link
FR (1) FR2097038A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4639529A (en) * 1982-02-19 1987-01-27 The Purdue Frederick Company Analgesic and anti-inflammatory compounds
JP2010513299A (en) * 2006-12-15 2010-04-30 アイアールエム・リミテッド・ライアビリティ・カンパニー Compounds and compositions as inhibitors of cannabinoid receptor 1 activity
US8101644B2 (en) 2007-03-30 2012-01-24 Shionogi & Co., Ltd. Pyrrolinone derivative and pharmaceutical composition comprising the same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH464924A (en) * 1965-12-09 1968-11-15 Geigy Ag J R Process for the preparation of new pyrrolidine derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH464924A (en) * 1965-12-09 1968-11-15 Geigy Ag J R Process for the preparation of new pyrrolidine derivatives

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4639529A (en) * 1982-02-19 1987-01-27 The Purdue Frederick Company Analgesic and anti-inflammatory compounds
JP2010513299A (en) * 2006-12-15 2010-04-30 アイアールエム・リミテッド・ライアビリティ・カンパニー Compounds and compositions as inhibitors of cannabinoid receptor 1 activity
US8431607B2 (en) 2006-12-15 2013-04-30 Irm Llc, A Delaware Limited Liability Company Compounds and compositions as inhibitors of cannabinoid receptor 1 activity
US8101644B2 (en) 2007-03-30 2012-01-24 Shionogi & Co., Ltd. Pyrrolinone derivative and pharmaceutical composition comprising the same
US8497263B2 (en) 2007-03-30 2013-07-30 Shionogi & Co., Ltd. Pyrrolinone derivative and pharmaceutical composition comprising the same

Also Published As

Publication number Publication date
FR2097038B1 (en) 1974-04-12

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Legal Events

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