FR2081564A1 - N-amino carbonyl-piperazines analgesics - antiinflammatories ,hypotensives and spasmolytics - Google Patents
N-amino carbonyl-piperazines analgesics - antiinflammatories ,hypotensives and spasmolyticsInfo
- Publication number
- FR2081564A1 FR2081564A1 FR7007821A FR7007821A FR2081564A1 FR 2081564 A1 FR2081564 A1 FR 2081564A1 FR 7007821 A FR7007821 A FR 7007821A FR 7007821 A FR7007821 A FR 7007821A FR 2081564 A1 FR2081564 A1 FR 2081564A1
- Authority
- FR
- France
- Prior art keywords
- hypotensives
- spasmolytics
- antiinflammatories
- piperazines
- analgesics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000001953 Hypotension Diseases 0.000 title 1
- 229940035676 analgesics Drugs 0.000 title 1
- 239000000730 antalgic agent Substances 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- 229940121363 anti-inflammatory agent Drugs 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 208000021822 hypotensive Diseases 0.000 title 1
- 230000001077 hypotensive effect Effects 0.000 title 1
- IVXQBCUBSIPQGU-UHFFFAOYSA-N piperazine-1-carboxamide Chemical class NC(=O)N1CCNCC1 IVXQBCUBSIPQGU-UHFFFAOYSA-N 0.000 title 1
- 230000002048 spasmolytic effect Effects 0.000 title 1
- -1 dihydroxyethyl Chemical group 0.000 abstract 3
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- OQURWGJAWSLGQG-UHFFFAOYSA-N 1-isocyanatopropane Chemical compound CCCN=C=O OQURWGJAWSLGQG-UHFFFAOYSA-N 0.000 abstract 1
- FFOHTSTWXWJGQR-UHFFFAOYSA-N 2-piperazin-1-yl-n-propan-2-ylacetamide Chemical compound CC(C)NC(=O)CN1CCNCC1 FFOHTSTWXWJGQR-UHFFFAOYSA-N 0.000 abstract 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 150000002688 maleic acid derivatives Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004742 propyloxycarbonyl group Chemical group 0.000 abstract 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7007821A FR2081564A1 (en) | 1970-03-05 | 1970-03-05 | N-amino carbonyl-piperazines analgesics - antiinflammatories ,hypotensives and spasmolytics |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7007821A FR2081564A1 (en) | 1970-03-05 | 1970-03-05 | N-amino carbonyl-piperazines analgesics - antiinflammatories ,hypotensives and spasmolytics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2081564A1 true FR2081564A1 (en) | 1971-12-10 |
| FR2081564B1 FR2081564B1 (https=) | 1973-04-06 |
Family
ID=9051697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7007821A Granted FR2081564A1 (en) | 1970-03-05 | 1970-03-05 | N-amino carbonyl-piperazines analgesics - antiinflammatories ,hypotensives and spasmolytics |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2081564A1 (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4247549A (en) * | 1978-12-27 | 1981-01-27 | Ici Americas Inc. | Piperazine-1-carboxylic acid esters possessing antidepressant or analgesic activity |
| EP0123977A1 (de) * | 1983-04-28 | 1984-11-07 | CASSELLA Aktiengesellschaft | Substituierte Piperazin-1-yl-essigsäure-amide, Verfahren zu ihrer Herstellung und ihre Verwendung |
| US4666911A (en) * | 1981-07-14 | 1987-05-19 | Taiho Pharmaceutical Company Limited | Allophanoylpiperazine compound and analgesic composition containing same as active ingredient |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE647594A (https=) * | 1963-06-28 | 1964-11-06 |
-
1970
- 1970-03-05 FR FR7007821A patent/FR2081564A1/fr active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE647594A (https=) * | 1963-06-28 | 1964-11-06 |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4247549A (en) * | 1978-12-27 | 1981-01-27 | Ici Americas Inc. | Piperazine-1-carboxylic acid esters possessing antidepressant or analgesic activity |
| US4666911A (en) * | 1981-07-14 | 1987-05-19 | Taiho Pharmaceutical Company Limited | Allophanoylpiperazine compound and analgesic composition containing same as active ingredient |
| EP0123977A1 (de) * | 1983-04-28 | 1984-11-07 | CASSELLA Aktiengesellschaft | Substituierte Piperazin-1-yl-essigsäure-amide, Verfahren zu ihrer Herstellung und ihre Verwendung |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2081564B1 (https=) | 1973-04-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |