FR2079314A1 - 2, 4-dioxo-1, 2, 3, 4, 5, 6, 7, 8-octahydrobenzothieno - (2, 3-d) pyrimidines - with antiinflammatory, analgesic, antitussive - Google Patents
2, 4-dioxo-1, 2, 3, 4, 5, 6, 7, 8-octahydrobenzothieno - (2, 3-d) pyrimidines - with antiinflammatory, analgesic, antitussiveInfo
- Publication number
- FR2079314A1 FR2079314A1 FR7006702A FR7006702A FR2079314A1 FR 2079314 A1 FR2079314 A1 FR 2079314A1 FR 7006702 A FR7006702 A FR 7006702A FR 7006702 A FR7006702 A FR 7006702A FR 2079314 A1 FR2079314 A1 FR 2079314A1
- Authority
- FR
- France
- Prior art keywords
- octahydrobenzothieno
- antitussive
- pyrimidines
- antiinflammatory
- dioxo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- FLBUBMOKRJJLKX-UHFFFAOYSA-N 5,6,7,8-tetrahydro-1h-[1]benzothiolo[2,3-d]pyrimidine-2,4-dione Chemical class C1CCCC2=C1SC1=C2C(=O)NC(=O)N1 FLBUBMOKRJJLKX-UHFFFAOYSA-N 0.000 title 1
- 230000000202 analgesic effect Effects 0.000 title 1
- 230000000954 anitussive effect Effects 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 229940124584 antitussives Drugs 0.000 title 1
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- WYOLDVOOOYZSJM-UHFFFAOYSA-N 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid Chemical class C1CCCC2=C1SC(N)=C2C(O)=O WYOLDVOOOYZSJM-UHFFFAOYSA-N 0.000 abstract 1
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- RIFGWPKJUGCATF-UHFFFAOYSA-N ethyl chloroformate Chemical compound CCOC(Cl)=O RIFGWPKJUGCATF-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- DGTNSSLYPYDJGL-UHFFFAOYSA-N phenyl isocyanate Chemical compound O=C=NC1=CC=CC=C1 DGTNSSLYPYDJGL-UHFFFAOYSA-N 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT114870A AT290525B (de) | 1970-02-09 | 1970-02-09 | Verfahren zur Herstellung des neuen 2,4-Dioxo-1,2,3,4,5,6,7,8-octahydro-[1]benzothieno[2,3-d]pyrimidins und dessen neuen 3-Phenyl-Derivats |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2079314A1 true FR2079314A1 (en) | 1971-11-12 |
| FR2079314B1 FR2079314B1 (enExample) | 1974-01-11 |
Family
ID=3507641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7006702A Granted FR2079314A1 (en) | 1970-02-09 | 1970-02-25 | 2, 4-dioxo-1, 2, 3, 4, 5, 6, 7, 8-octahydrobenzothieno - (2, 3-d) pyrimidines - with antiinflammatory, analgesic, antitussive |
Country Status (2)
| Country | Link |
|---|---|
| AT (1) | AT290525B (enExample) |
| FR (1) | FR2079314A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2128348A1 (en) * | 1971-03-08 | 1972-10-20 | Centre Etd Ind Pharma | Mercapto-thienopyrimidine derivs - with sedative antitussive and hypocholesterolaemic activity |
-
1970
- 1970-02-09 AT AT114870A patent/AT290525B/de not_active IP Right Cessation
- 1970-02-25 FR FR7006702A patent/FR2079314A1/fr active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2128348A1 (en) * | 1971-03-08 | 1972-10-20 | Centre Etd Ind Pharma | Mercapto-thienopyrimidine derivs - with sedative antitussive and hypocholesterolaemic activity |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2079314B1 (enExample) | 1974-01-11 |
| AT290525B (de) | 1971-06-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |