FR2055903A5 - - Google Patents

Info

Publication number
FR2055903A5
FR2055903A5 FR6926912A FR6926912A FR2055903A5 FR 2055903 A5 FR2055903 A5 FR 2055903A5 FR 6926912 A FR6926912 A FR 6926912A FR 6926912 A FR6926912 A FR 6926912A FR 2055903 A5 FR2055903 A5 FR 2055903A5
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR6926912A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc SA
Original Assignee
Rhone Poulenc SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE754412A priority Critical patent/BE754412A/xx
Priority to BE754411A priority patent/BE754411A/xx
Application filed by Rhone Poulenc SA filed Critical Rhone Poulenc SA
Priority to FR6926912A priority patent/FR2055903A5/fr
Priority to NL7011151A priority patent/NL7011151A/xx
Priority to NL7011150.A priority patent/NL164900C/xx
Priority to SE10691/70A priority patent/SE369713B/xx
Priority to GB3763370A priority patent/GB1331435A/en
Priority to ZA705378A priority patent/ZA705378B/xx
Priority to CA089,920*7A priority patent/CA950391A/en
Priority to CA089921A priority patent/CA937569A/en
Priority to CH1173470A priority patent/CH513817A/fr
Priority to GB3763270A priority patent/GB1323362A/en
Priority to ZA705377A priority patent/ZA705377B/xx
Priority to JP45067805A priority patent/JPS4829149B1/ja
Priority to SE1069270A priority patent/SE382979B/xx
Priority to CH1173370A priority patent/CH521343A/fr
Priority to AT712970A priority patent/AT295746B/de
Priority to DE19702038997 priority patent/DE2038997A1/de
Priority to CS5473A priority patent/CS152369B2/cs
Priority to DE19702038996 priority patent/DE2038996A1/de
Priority to AT712870A priority patent/AT299977B/de
Application granted granted Critical
Publication of FR2055903A5 publication Critical patent/FR2055903A5/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/063—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/064—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for omega-amino or -guanidino functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62—Polymyxins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FR6926912A 1969-08-05 1969-08-05 Expired FR2055903A5 (enExample)

Priority Applications (21)

Application Number Priority Date Filing Date Title
BE754412A BE754412A (fr) 1969-08-05 Procede de protection de radicaux amino par un groupement pyridylmethyloxycarbonyle ou l'un de ses derives
BE754411A BE754411A (fr) 1969-08-05 Cyclopeptides derives des polymyxines et leur
FR6926912A FR2055903A5 (enExample) 1969-08-05 1969-08-05
NL7011150.A NL164900C (nl) 1969-08-05 1970-07-28 Werkwijze voor het bereiden van cyclische polypeptid en werkwijze voor het bereiden van natuurlijke en half- synthetische polymyxinen, werkwijze voor het bereiden van een antimicrobieel preparaat en gevormd preparaat.
NL7011151A NL7011151A (enExample) 1969-08-05 1970-07-28
SE1069270A SE382979B (sv) 1969-08-05 1970-08-04 Forfarande for skyddande av aminogrupper
ZA705378A ZA705378B (en) 1969-08-05 1970-08-04 Process for protecting amino radicals by a pyridylmethoxycarbonyl group or derivative thereof
CA089,920*7A CA950391A (en) 1969-08-05 1970-08-04 Cyclopeptides derives des polymyxines et leur preparation
CA089921A CA937569A (en) 1969-08-05 1970-08-04 Procede de protection de radicaux amino par un groupement pyridylmethyoxycarbonyle ou l'un de ses derives
CH1173470A CH513817A (fr) 1969-08-05 1970-08-04 Procédé de préparation de cyclopeptides dérivés des polymyxines
SE10691/70A SE369713B (enExample) 1969-08-05 1970-08-04
ZA705377A ZA705377B (en) 1969-08-05 1970-08-04 Cyclopeptides derived from polymyxins and their preparation
JP45067805A JPS4829149B1 (enExample) 1969-08-05 1970-08-04
GB3763370A GB1331435A (en) 1969-08-05 1970-08-04 Process for protecting amino radicals in polyfunctional compounds containing one or more amino radicals
CH1173370A CH521343A (fr) 1969-08-05 1970-08-04 Procédé d'obtention de composés comportant un ou plusieurs groupes amino protégés
GB3763270A GB1323362A (en) 1969-08-05 1970-08-04 Cyclopeptides derived from polymyxins and their preparation
AT712970A AT295746B (de) 1969-08-05 1970-08-05 Verfahren zur Herstellung von neuen, von Polymyxinen abgeleiteten Cyclopeptiden
DE19702038997 DE2038997A1 (de) 1969-08-05 1970-08-05 Von Polymyxinen abgeleitete Cyclopeptide und ihre Herstellung
CS5473A CS152369B2 (enExample) 1969-08-05 1970-08-05
DE19702038996 DE2038996A1 (de) 1969-08-05 1970-08-05 Verfahren zum Schutz von Aminoresten mit einer Pyridylmethyloxycarbonylgruppe oder einem ihrer Derivate
AT712870A AT299977B (de) 1969-08-05 1970-08-05 Verfahren zum Schützen von Aminoresten

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6926912A FR2055903A5 (enExample) 1969-08-05 1969-08-05

Publications (1)

Publication Number Publication Date
FR2055903A5 true FR2055903A5 (enExample) 1971-05-14

Family

ID=9038672

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6926912A Expired FR2055903A5 (enExample) 1969-08-05 1969-08-05

Country Status (12)

Country Link
JP (1) JPS4829149B1 (enExample)
AT (2) AT299977B (enExample)
BE (1) BE754411A (enExample)
CA (1) CA950391A (enExample)
CH (1) CH513817A (enExample)
CS (1) CS152369B2 (enExample)
DE (1) DE2038997A1 (enExample)
FR (1) FR2055903A5 (enExample)
GB (1) GB1323362A (enExample)
NL (1) NL164900C (enExample)
SE (1) SE369713B (enExample)
ZA (2) ZA705378B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2128617A (en) * 1982-10-06 1984-05-02 Martti Vaara Polypeptides for use in antibacterial therapy
US7807637B2 (en) 2006-08-11 2010-10-05 Northern Antibiotics Oy Polymyxin derivatives and uses thereof
BRPI0715095B8 (pt) 2006-08-11 2021-05-25 Northern Antibiotics Oy derivado de polimixina da fórmula geral (i); produto de combinação; composição farmacêutica; método para se sensibilizar bactérias gram-negativas a um agente antibacteriano; método para o desenvolvimento de antibióticos; método para a redução da toxicidade de polimixinas, octapeptinas naturais e seus derivados durante a aplicação das mesmas no tratamento de infecções em um indivíduo; método para melhorar as propriedades farmacocinéticas, de polimixinas, octapeptinas naturais e seus derivados; método para a sensibilização de bactérias gram-negativas clinicamente importantes a um complemento de mecanismo de defesa presente no soro; uso de um derivado; e processo para a preparação de um derivado de polimixina da fórmula (i).
US9096649B2 (en) 2008-02-08 2015-08-04 Northern Antibiotics Ltd. Polymyxin derivatives and uses thereof
US8193148B2 (en) 2008-02-08 2012-06-05 Northern Antibiotics Ltd. Short fatty acid tail polymyxin derivatives and uses thereof
US8329645B2 (en) 2008-02-08 2012-12-11 Northern Antibiotics Ltd. Polymyxin derivatives and uses thereof
FI126143B (en) * 2015-01-15 2016-07-15 Northern Antibiotics Oy Polymyxine derivative and its uses

Also Published As

Publication number Publication date
ZA705378B (en) 1971-04-28
NL164900C (nl) 1981-02-16
ZA705377B (en) 1971-04-28
NL164900B (nl) 1980-09-15
GB1323362A (en) 1973-07-11
AT295746B (de) 1972-01-10
AT299977B (de) 1972-07-10
CA950391A (en) 1974-07-02
CS152369B2 (enExample) 1973-12-19
SE369713B (enExample) 1974-09-16
BE754411A (fr) 1971-02-04
JPS4829149B1 (enExample) 1973-09-07
NL7011150A (enExample) 1971-02-09
CH513817A (fr) 1971-10-15
DE2038997A1 (de) 1971-02-18

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Legal Events

Date Code Title Description
ST Notification of lapse