FR2054507A1 - (3 alkoxy-2-(diaryl) methyl)-propylamines cardio - vascular pharmaceuticals - Google Patents
(3 alkoxy-2-(diaryl) methyl)-propylamines cardio - vascular pharmaceuticalsInfo
- Publication number
- FR2054507A1 FR2054507A1 FR6924645A FR6924645A FR2054507A1 FR 2054507 A1 FR2054507 A1 FR 2054507A1 FR 6924645 A FR6924645 A FR 6924645A FR 6924645 A FR6924645 A FR 6924645A FR 2054507 A1 FR2054507 A1 FR 2054507A1
- Authority
- FR
- France
- Prior art keywords
- diaryl
- propylamines
- alkoxy
- methyl
- pharmaceuticals
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
- C07D311/90—Xanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
Abstract
3-Alkoxy-2-(diaryl)methyl -propylamines, cardiovascular pharmaceuticals Cpds. of formula (where Ar and Ar' are opt. subst aryl which may be linked in the form of polynuclear aromatic group by C-C bonds or chains containing heteroatoms and oxygen, R is aliphatic residue, aryl or arylaliphatic residue, and A is tert. amino group where N-atom may form part of heterocycle). are obtained by replacing OH-group of aminoalcohol by Cl-atom and reacting intermediate in solvent with diaryl derivative of methane that has previously been converted to sodium derivative and whose aryl residues correspond to the residues Ar and Ar' of the required product.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR6924645A FR2054507A1 (en) | 1969-07-18 | 1969-07-18 | (3 alkoxy-2-(diaryl) methyl)-propylamines cardio - vascular pharmaceuticals |
JP45061100A JPS4941428B1 (en) | 1969-07-18 | 1970-07-14 | |
DE19702035535 DE2035535A1 (en) | 1969-07-18 | 1970-07-17 | Square bracket on 3 alkoxy 2 (diaryl) methyl square bracket on propylamine, its manufacture and use |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR6924645A FR2054507A1 (en) | 1969-07-18 | 1969-07-18 | (3 alkoxy-2-(diaryl) methyl)-propylamines cardio - vascular pharmaceuticals |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2054507A1 true FR2054507A1 (en) | 1971-04-23 |
FR2054507B1 FR2054507B1 (en) | 1973-06-08 |
Family
ID=9037713
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR6924645A Granted FR2054507A1 (en) | 1969-07-18 | 1969-07-18 | (3 alkoxy-2-(diaryl) methyl)-propylamines cardio - vascular pharmaceuticals |
Country Status (3)
Country | Link |
---|---|
JP (1) | JPS4941428B1 (en) |
DE (1) | DE2035535A1 (en) |
FR (1) | FR2054507A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993001160A1 (en) * | 1991-07-05 | 1993-01-21 | Merck Sharp & Dohme Limited | Aromatic compounds, pharmaceutical compositions containing them and their use in therapy |
WO1993001159A1 (en) * | 1991-07-10 | 1993-01-21 | Merck Sharp & Dohme Limited | Fused tricyclic compounds, pharmaceutical compositions containing them and their use in therapy |
GB9211193D0 (en) * | 1992-05-27 | 1992-07-08 | Merck Sharp & Dohme | Therapeutic agents |
GB9300051D0 (en) * | 1993-01-04 | 1993-03-03 | Merck Sharp & Dohme | Therapeutic agents |
-
1969
- 1969-07-18 FR FR6924645A patent/FR2054507A1/en active Granted
-
1970
- 1970-07-14 JP JP45061100A patent/JPS4941428B1/ja active Pending
- 1970-07-17 DE DE19702035535 patent/DE2035535A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
DE2035535A1 (en) | 1971-01-28 |
JPS4941428B1 (en) | 1974-11-08 |
FR2054507B1 (en) | 1973-06-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |