FR2047875A1 - Antileukaemic aziridinyl pyrimidines - Google Patents

Antileukaemic aziridinyl pyrimidines

Info

Publication number
FR2047875A1
FR2047875A1 FR6919292A FR6919292A FR2047875A1 FR 2047875 A1 FR2047875 A1 FR 2047875A1 FR 6919292 A FR6919292 A FR 6919292A FR 6919292 A FR6919292 A FR 6919292A FR 2047875 A1 FR2047875 A1 FR 2047875A1
Authority
FR
France
Prior art keywords
antileukaemic
aziridinyl
pyrimidines
aziridine
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR6919292A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ugine Kuhlmann SA
Original Assignee
Ugine Kuhlmann SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ugine Kuhlmann SA filed Critical Ugine Kuhlmann SA
Priority to FR6919292A priority Critical patent/FR2047875A1/en
Publication of FR2047875A1 publication Critical patent/FR2047875A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Aziridine derivs. of formula (I) are prepd. by the reaction of a pyrimidine (II) with an aziridine (III) in the presence of an acid binding agent: (where R is alkyl or aralkyl; one X is halogen and the other 2X groups are: X1 is halogen and R1 is H or lower alkyl).
FR6919292A 1969-06-11 1969-06-11 Antileukaemic aziridinyl pyrimidines Withdrawn FR2047875A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR6919292A FR2047875A1 (en) 1969-06-11 1969-06-11 Antileukaemic aziridinyl pyrimidines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6919292A FR2047875A1 (en) 1969-06-11 1969-06-11 Antileukaemic aziridinyl pyrimidines

Publications (1)

Publication Number Publication Date
FR2047875A1 true FR2047875A1 (en) 1971-03-19

Family

ID=9035537

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6919292A Withdrawn FR2047875A1 (en) 1969-06-11 1969-06-11 Antileukaemic aziridinyl pyrimidines

Country Status (1)

Country Link
FR (1) FR2047875A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2675386A (en) * 1950-02-28 1954-04-13 Ici Ltd 2-4-diethyleneimino pyrimidines and process of preparing same
FR1549494A (en) * 1967-10-31 1968-12-13

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2675386A (en) * 1950-02-28 1954-04-13 Ici Ltd 2-4-diethyleneimino pyrimidines and process of preparing same
FR1549494A (en) * 1967-10-31 1968-12-13

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse