FR2034995A1 - 3-carbalkoxy-1-thia-isochroman-1,1-dioxides - Google Patents

3-carbalkoxy-1-thia-isochroman-1,1-dioxides

Info

Publication number
FR2034995A1
FR2034995A1 FR7009312A FR7009312A FR2034995A1 FR 2034995 A1 FR2034995 A1 FR 2034995A1 FR 7009312 A FR7009312 A FR 7009312A FR 7009312 A FR7009312 A FR 7009312A FR 2034995 A1 FR2034995 A1 FR 2034995A1
Authority
FR
France
Prior art keywords
carbalkoxy
dioxides
thia
coor4
substd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7009312A
Other languages
French (fr)
Other versions
FR2034995B1 (en
Inventor
Werner Poepel
Gottfried Faust
Kurt Stade
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AWD Pharma GmbH and Co KG
Original Assignee
Arzneimittelwerk Dresden GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arzneimittelwerk Dresden GmbH filed Critical Arzneimittelwerk Dresden GmbH
Publication of FR2034995A1 publication Critical patent/FR2034995A1/en
Application granted granted Critical
Publication of FR2034995B1 publication Critical patent/FR2034995B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/06Six-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/39Heterocyclic compounds having sulfur as a ring hetero atom having oxygen in the same ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

3-Carbalkoxy-1-thia-isochromane-1,1-dioxides. The new cpds. having marked pharmacodynamic action on the central nervous system are of formula: (where R1 and R2 are lower alkyl; R3 is H or lower alkyl; and R4 is alkyl, opt. substd. with halogen, aryl or heterocyclic residues or cycloalkyl) are prepd. (i) by esterification of the acid (or acid chloride) with R4OH, (ii) by ring closure of the corresp. ammonium O-(-CH2CR3(Hal)COOR4)-phenylsulphonate, or (iii) reacting the substd. BzCR3(OH)COOR4 with conc. H2SO4.
FR7009312A 1969-03-17 1970-03-16 3-carbalkoxy-1-thia-isochroman-1,1-dioxides Granted FR2034995A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DD13859869 1969-03-17

Publications (2)

Publication Number Publication Date
FR2034995A1 true FR2034995A1 (en) 1970-12-18
FR2034995B1 FR2034995B1 (en) 1973-07-13

Family

ID=5481042

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7009312A Granted FR2034995A1 (en) 1969-03-17 1970-03-16 3-carbalkoxy-1-thia-isochroman-1,1-dioxides

Country Status (12)

Country Link
AT (2) AT295531B (en)
BG (3) BG18184A3 (en)
CH (1) CH530996A (en)
CS (3) CS166361B1 (en)
DE (1) DE2011024A1 (en)
DK (1) DK123722B (en)
FI (1) FI49975C (en)
FR (1) FR2034995A1 (en)
PL (1) PL79282B1 (en)
RO (3) RO58873A (en)
SE (1) SE364048B (en)
SU (3) SU413679A3 (en)

Also Published As

Publication number Publication date
RO58741A (en) 1975-11-15
CH530996A (en) 1972-11-30
CS166361B1 (en) 1976-02-27
SE364048B (en) 1974-02-11
SU413679A3 (en) 1974-01-30
DE2011024A1 (en) 1970-09-24
FR2034995B1 (en) 1973-07-13
BG17563A3 (en) 1973-11-10
AT295531B (en) 1971-12-15
SU493960A3 (en) 1975-11-28
FI49975B (en) 1975-07-31
BG18183A3 (en) 1974-09-02
RO57971A (en) 1975-06-15
SU390719A3 (en) 1973-07-11
PL79282B1 (en) 1975-06-30
DK123722B (en) 1972-07-24
CS166362B1 (en) 1976-02-27
RO58873A (en) 1975-10-15
AT296982B (en) 1972-02-15
CS166363B1 (en) 1976-02-27
FI49975C (en) 1975-11-10
BG18184A3 (en) 1974-09-02

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