FR2007534A1 - 1,4 Benzodiazepine derivs. - sedatives muscle relaxants - Google Patents

1,4 Benzodiazepine derivs. - sedatives muscle relaxants

Info

Publication number
FR2007534A1
FR2007534A1 FR6913239A FR6913239A FR2007534A1 FR 2007534 A1 FR2007534 A1 FR 2007534A1 FR 6913239 A FR6913239 A FR 6913239A FR 6913239 A FR6913239 A FR 6913239A FR 2007534 A1 FR2007534 A1 FR 2007534A1
Authority
FR
France
Prior art keywords
alkyl
muscle relaxants
sedatives
subst
opt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR6913239A
Other languages
French (fr)
Other versions
FR2007534B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Priority to FR6913239A priority Critical patent/FR2007534A1/en
Publication of FR2007534A1 publication Critical patent/FR2007534A1/en
Application granted granted Critical
Publication of FR2007534B1 publication Critical patent/FR2007534B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

a) Improved method of prepn. for cpds. of general formula (I) and salts thereof where R1=H, halogen, (1-4C) alkyl, (1-4C) O-alkyl, or CF3. R2=(1-6C) alkyl or aralkyl and R3=H, (1-4C) alkyl, aralkyl, cycloalkylalkyl, or Ph opt. subst. by halogen. b) The cpds. Y=H or OH and W=O or S (IV)I where R3=Ph opt. subst. by hal. R5=lower alkyl, aralkyl, cycloalkylalkyl, opt. halo-subst. phenyl. R4 = H or (1-4C) alkyl. Tranquillisers, muscle relaxants, antispasmodics, and analgesics.
FR6913239A 1969-04-25 1969-04-25 1,4 Benzodiazepine derivs. - sedatives muscle relaxants Granted FR2007534A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR6913239A FR2007534A1 (en) 1969-04-25 1969-04-25 1,4 Benzodiazepine derivs. - sedatives muscle relaxants

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6913239A FR2007534A1 (en) 1969-04-25 1969-04-25 1,4 Benzodiazepine derivs. - sedatives muscle relaxants

Publications (2)

Publication Number Publication Date
FR2007534A1 true FR2007534A1 (en) 1970-01-09
FR2007534B1 FR2007534B1 (en) 1974-08-30

Family

ID=9033083

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6913239A Granted FR2007534A1 (en) 1969-04-25 1969-04-25 1,4 Benzodiazepine derivs. - sedatives muscle relaxants

Country Status (1)

Country Link
FR (1) FR2007534A1 (en)

Also Published As

Publication number Publication date
FR2007534B1 (en) 1974-08-30

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Legal Events

Date Code Title Description
ST Notification of lapse