FR1516142A - New process for the preparation of phenothiazine derivatives - Google Patents

New process for the preparation of phenothiazine derivatives

Info

Publication number
FR1516142A
FR1516142A FR92352A FR92352A FR1516142A FR 1516142 A FR1516142 A FR 1516142A FR 92352 A FR92352 A FR 92352A FR 92352 A FR92352 A FR 92352A FR 1516142 A FR1516142 A FR 1516142A
Authority
FR
France
Prior art keywords
general formula
phenthiazine
known methods
preparation
new process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR92352A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc SA
Original Assignee
Rhone Poulenc SA
Societe des Usines Chimiques Rhone Poulenc SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc SA, Societe des Usines Chimiques Rhone Poulenc SA filed Critical Rhone Poulenc SA
Priority to FR92352A priority Critical patent/FR1516142A/en
Priority to AT1028767A priority patent/AT269890B/en
Priority to NL6800658A priority patent/NL6800658A/xx
Priority to DK22068A priority patent/DK112095B/en
Priority to FI16268A priority patent/FI49046C/en
Priority to CH1766569A priority patent/CH487178A/en
Priority to SE90568A priority patent/SE368405B/xx
Priority to CH101868A priority patent/CH484935A/en
Priority to GB358968A priority patent/GB1142760A/en
Priority to ES349689A priority patent/ES349689A1/en
Application granted granted Critical
Publication of FR1516142A publication Critical patent/FR1516142A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Catalysts (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

1,142,760. Phenthiazine derivatives. RHONEPOULENC S.A. 23 Jan., 1968 [24 Jan., 1967], No. 3589/68. Heading C2C. 3 - Carboxyalkyl - phenthiazines of the general formula where R represents H, or CH 3 , R 1 represents H, CH 3 or ethyl and Y represents H, or halogen, or an alkyl, alkoxy, or alkylthio group having 1 to 4 carbon atoms, are obtained in a process which comprises heating in the presence of a trialkyl phosphite a diphenylsulphide of the general formula where T 1 represents a lower alkoxycarbonyl group and R 1 and Y are as above, and hydrolysing by known methods the resulting 3-alkoxycarbonylalkyl-phenthiazine compound of general formula where R 1 , T 1 and Y are as above, to obtain as product a phenthiazine derivative of general Formula (I) where R represents H, or N-methylating by known methods the 3-alkoxycarbonylalkyl-phenthiazine intermediate and hydrolysing by known methods the resulting 3-alkoxycarbonyl alkyl-10-methylphenthiazine to obtain as product a phenthiazine derivative of general Formula (I), where R represents a methyl group.
FR92352A 1967-01-24 1967-01-24 New process for the preparation of phenothiazine derivatives Expired FR1516142A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
FR92352A FR1516142A (en) 1967-01-24 1967-01-24 New process for the preparation of phenothiazine derivatives
AT1028767A AT269890B (en) 1967-01-24 1967-11-15 Process for the preparation of phenthiazine derivatives
NL6800658A NL6800658A (en) 1967-01-24 1968-01-16
DK22068A DK112095B (en) 1967-01-24 1968-01-19 Process for the preparation of phenthiazine derivatives.
FI16268A FI49046C (en) 1967-01-24 1968-01-22 Methods of preparing phenothiazine derivatives.
CH1766569A CH487178A (en) 1967-01-24 1968-01-23 Process for the preparation of phenothiazine derivatives
SE90568A SE368405B (en) 1967-01-24 1968-01-23
CH101868A CH484935A (en) 1967-01-24 1968-01-23 Process for the preparation of phenothiazine derivatives
GB358968A GB1142760A (en) 1967-01-24 1968-01-23 Process for the preparation of phenthiazine derivatives
ES349689A ES349689A1 (en) 1967-01-24 1968-01-24 Process for the preparation of phenthiazine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR92352A FR1516142A (en) 1967-01-24 1967-01-24 New process for the preparation of phenothiazine derivatives

Publications (1)

Publication Number Publication Date
FR1516142A true FR1516142A (en) 1968-03-08

Family

ID=8624310

Family Applications (1)

Application Number Title Priority Date Filing Date
FR92352A Expired FR1516142A (en) 1967-01-24 1967-01-24 New process for the preparation of phenothiazine derivatives

Country Status (9)

Country Link
AT (1) AT269890B (en)
CH (1) CH484935A (en)
DK (1) DK112095B (en)
ES (1) ES349689A1 (en)
FI (1) FI49046C (en)
FR (1) FR1516142A (en)
GB (1) GB1142760A (en)
NL (1) NL6800658A (en)
SE (1) SE368405B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR68102B (en) * 1978-08-08 1981-10-30 Fujisawa Pharmaceutical Co

Also Published As

Publication number Publication date
DK112095B (en) 1968-11-11
ES349689A1 (en) 1969-04-01
FI49046C (en) 1975-03-10
CH484935A (en) 1970-01-31
GB1142760A (en) 1969-02-12
SE368405B (en) 1974-07-01
FI49046B (en) 1974-12-02
AT269890B (en) 1969-04-10
NL6800658A (en) 1968-07-25

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