FR13C0035I1 - - Google Patents
Info
- Publication number
- FR13C0035I1 FR13C0035I1 FR13C0035C FR13C0035I1 FR 13C0035 I1 FR13C0035 I1 FR 13C0035I1 FR 13C0035 C FR13C0035 C FR 13C0035C FR 13C0035 I1 FR13C0035 I1 FR 13C0035I1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200301129 | 2003-08-05 | ||
| US49545103P | 2003-08-14 | 2003-08-14 | |
| EP04739008A EP1660531A2 (en) | 2003-08-05 | 2004-07-22 | Novel insulin derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR13C0035I1 true FR13C0035I1 (en) | 2013-08-09 |
| FR13C0035I2 FR13C0035I2 (en) | 2014-03-07 |
Family
ID=34117520
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR13C0035C Active FR13C0035I2 (en) | 2003-08-05 | 2013-07-04 | NEW INSULIN DERIVATIVES |
| FR13C0038C Active FR13C0038I1 (en) | 2003-08-05 | 2013-07-05 | NEW INSULIN DERIVATIVES |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR13C0038C Active FR13C0038I1 (en) | 2003-08-05 | 2013-07-05 | NEW INSULIN DERIVATIVES |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US7615532B2 (en) |
| EP (3) | EP2107069B1 (en) |
| JP (1) | JP4463814B2 (en) |
| KR (1) | KR101159559B1 (en) |
| AU (2) | AU2004261353B2 (en) |
| BE (2) | BE2013C035I2 (en) |
| BR (1) | BRPI0413276B8 (en) |
| CA (1) | CA2531988C (en) |
| CY (3) | CY1113850T1 (en) |
| FR (2) | FR13C0035I2 (en) |
| HU (1) | HUS1300033I1 (en) |
| IL (1) | IL172980A (en) |
| LU (2) | LU92213I2 (en) |
| MX (1) | MXPA06001283A (en) |
| NO (3) | NO340925B1 (en) |
| PL (1) | PL2107069T3 (en) |
| RU (1) | RU2518460C2 (en) |
| WO (1) | WO2005012347A2 (en) |
Families Citing this family (95)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007520441A (en) * | 2003-07-25 | 2007-07-26 | コンジュシェム，インコーポレイティド | Persistent insulin derivatives and methods thereof |
| EP2107069B1 (en) | 2003-08-05 | 2013-01-16 | Novo Nordisk A/S | Novel insulin derivatives |
| ES2438145T3 (en) * | 2005-02-02 | 2014-01-16 | Novo Nordisk A/S | New insulin derivatives |
| EP2292653B1 (en) * | 2005-02-02 | 2014-05-21 | Novo Nordisk A/S | Novel insulin derivatives |
| PT1969004E (en) | 2005-12-28 | 2011-11-25 | Novo Nordisk As | Compositions comprising an acylated insulin and zinc and method of making the said compositions |
| EP2256129B1 (en) | 2006-02-27 | 2012-05-09 | Novo Nordisk A/S | Insulin derivatives |
| WO2007104736A2 (en) * | 2006-03-13 | 2007-09-20 | Novo Nordisk A/S | Acylated single chain insulin |
| US8293965B2 (en) | 2006-04-28 | 2012-10-23 | Kimberly-Clark Worldwide, Inc. | Antimicrobial site dressings |
| CN101437849B (en) * | 2006-05-09 | 2015-09-30 | 诺沃-诺迪斯克有限公司 | Insulin derivates |
| JP5269766B2 (en) * | 2006-05-09 | 2013-08-21 | ノボ・ノルデイスク・エー／エス | Insulin derivative |
| MX2008014061A (en) * | 2006-05-09 | 2008-11-14 | Novo Nordisk As | Insulin derivative. |
| JP5097900B2 (en) * | 2006-06-27 | 2012-12-12 | 独立行政法人物質・材料研究機構 | Method for producing active ester of organic acid or derivative thereof |
| EP2049149B1 (en) * | 2006-07-31 | 2015-04-15 | Novo Nordisk A/S | Pegylated extended insulins |
| KR101729986B1 (en) | 2006-09-22 | 2017-04-25 | 노보 노르디스크 에이/에스 | Protease resistant insulin analogues |
| CN101674812B (en) | 2007-04-30 | 2013-12-11 | 诺沃-诺迪斯克有限公司 | Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein |
| EP2514406A1 (en) | 2007-06-01 | 2012-10-24 | Novo Nordisk A/S | Spontaneously dispersible preconcentrates including a peptide drug in a solid or semisolid carrier |
| JP5628026B2 (en) * | 2007-06-01 | 2014-11-19 | ノボ・ノルデイスク・エー／エス | Stable non-aqueous pharmaceutical composition |
| JP5552046B2 (en) * | 2007-06-13 | 2014-07-16 | ノボ・ノルデイスク・エー／エス | Pharmaceutical preparation containing an insulin derivative |
| US8962794B2 (en) | 2007-08-15 | 2015-02-24 | Novo Nordisk A/S | Insulins with an acyl moiety comprising repeating units of alkylene glycol containing amino acids |
| AU2008288413B2 (en) | 2007-08-15 | 2013-09-26 | Novo Nordisk A/S | Insulin analogues with an acyl and aklylene glycol moiety |
| CN101157725B (en) * | 2007-10-24 | 2012-07-25 | 中国药科大学 | Preparation method of human insulin analogue and usage thereof |
| JP5715418B2 (en) * | 2007-11-08 | 2015-05-07 | ノボ・ノルデイスク・エー／エス | Insulin derivative |
| MX2010005245A (en) | 2007-11-16 | 2010-06-01 | Novo Nordisk As | Pharmaceutical compositions containing insulin and an insulinotropic peptide. |
| ES2618073T3 (en) | 2008-03-14 | 2017-06-20 | Novo Nordisk A/S | Insulin analogs stabilized against proteases |
| DK2910570T3 (en) | 2008-03-18 | 2017-01-30 | Novo Nordisk As | Protease-stabilized acylated insulin analogues. |
| EP2340049B1 (en) | 2008-09-12 | 2015-11-11 | Novo Nordisk A/S | Method of acylating a peptide or protein |
| EP2352513B1 (en) | 2008-10-30 | 2016-09-14 | Novo Nordisk A/S | Treating diabetes melitus using insulin injections with less than daily injection frequency |
| US9480753B2 (en) | 2009-01-23 | 2016-11-01 | Novo Nordisk A/S | FGF21 derivatives with albumin binder A-B-C-D-E- and their use |
| CN102666579A (en) | 2009-10-30 | 2012-09-12 | 诺沃—诺迪斯克有限公司 | Derivatives of CGRP |
| MX2012007806A (en) * | 2010-01-12 | 2012-08-01 | Novo Nordisk As | Pharmaceutical compositions for oral administration of insulin peptides. |
| US20130012684A1 (en) | 2010-02-16 | 2013-01-10 | Novo Nordisk A/S | Purification Method |
| JP5826772B2 (en) | 2010-02-16 | 2015-12-02 | ノヴォ ノルディスク アー／エス | Conjugate protein |
| BR112012028766A2 (en) | 2010-05-10 | 2017-06-13 | Novo Nordisk As | process for the preparation of insulin and zinc complexes |
| WO2011146972A1 (en) | 2010-05-25 | 2011-12-01 | Monash University | Methods for the synthesis of dicarba bridges in peptides |
| CN102985440B (en) | 2010-06-23 | 2016-10-26 | 诺沃-诺迪斯克有限公司 | Comprise the insulin derivates of extra disulfide bond |
| JP5973427B2 (en) | 2010-06-23 | 2016-08-23 | ノヴォ ノルディスク アー／エス | Insulin analogues containing additional disulfide bonds |
| US8883722B2 (en) | 2010-06-23 | 2014-11-11 | Novo Nordisk A/S | Human insulin containing additional disulfide bonds |
| JP2013540771A (en) | 2010-10-15 | 2013-11-07 | ノヴォ ノルディスク アー／エス | Novel N-terminally modified insulin derivative |
| RU2013123515A (en) * | 2010-10-27 | 2014-12-10 | Ново Нордиск А/С | DIABETES TREATMENT USING INSULIN INJECTIONS INJECTED WITH VARIOUS INTERVALS |
| MX366314B (en) * | 2010-10-27 | 2019-07-05 | Novo Nordisk As | Treating diabetes melitus using insulin injections administered with varying injection intervals. |
| JP2013545782A (en) | 2010-12-14 | 2013-12-26 | ノヴォ ノルディスク アー／エス | Fast-acting insulin combined with long-acting insulin |
| EP2675470A1 (en) | 2011-02-15 | 2013-12-25 | Novo Nordisk A/S | Long-acting il-1 receptor antagonists |
| AU2012234276A1 (en) * | 2011-03-28 | 2013-08-29 | Novo Nordisk A/S | Novel glucagon analogues |
| EP2696847A1 (en) | 2011-04-14 | 2014-02-19 | Novo Nordisk A/S | Fatty acid acylated amino acids for oral peptide delivery |
| WO2012171994A1 (en) | 2011-06-15 | 2012-12-20 | Novo Nordisk A/S | Multi substituted insulins |
| AU2012311484B2 (en) | 2011-09-23 | 2017-04-13 | Novo Nordisk A/S | Novel glucagon analogues |
| IN2014MN00933A (en) * | 2011-12-15 | 2015-05-01 | Shanghai Hengrui Pharm Co Ltd | |
| JP2015502971A (en) | 2011-12-21 | 2015-01-29 | ノヴォ ノルディスク アー／エス | N-terminal modified insulin derivative |
| CN104364260B (en) | 2012-04-11 | 2017-02-22 | 诺和诺德股份有限公司 | insulin formulations |
| US20160031962A1 (en) * | 2012-04-20 | 2016-02-04 | Kleomenis K. Barlos | Solid phase peptide synthesis of insulin using side chain achored lysine |
| WO2013164375A1 (en) | 2012-05-01 | 2013-11-07 | Novo Nordisk A/S | Pharmaceutical composition |
| EP2869830B1 (en) | 2012-07-09 | 2016-10-12 | Novo Nordisk A/S | Novel use of insulin derivatives |
| UA116217C2 (en) | 2012-10-09 | 2018-02-26 | Санофі | Exendin-4 derivatives as dual glp1/glucagon agonists |
| WO2014060447A1 (en) | 2012-10-17 | 2014-04-24 | Novo Nordisk A/S | Fatty acid acylated d-amino acids for oral peptide delivery |
| ES2653765T3 (en) | 2012-12-21 | 2018-02-08 | Sanofi | Dual GLP1 / GIP or trigonal GLP1 / GIP / glucagon agonists |
| JP6755175B2 (en) * | 2013-03-20 | 2020-09-16 | ノヴォ ノルディスク アー／エス | Insulin medication regimen |
| RS59124B1 (en) | 2013-04-18 | 2019-09-30 | Novo Nordisk As | Stable, protracted glp-1/glucagon receptor co-agonists for medical use |
| US10137172B2 (en) | 2013-04-30 | 2018-11-27 | Novo Nordisk A/S | Administration regime |
| GB201315335D0 (en) | 2013-08-29 | 2013-10-09 | Of Singapore | Amino diacids containing peptide modifiers |
| CA2926701A1 (en) | 2013-10-07 | 2015-04-16 | Novo Nordisk A/S | Novel derivative of an insulin analogue |
| FR3013049B1 (en) | 2013-11-14 | 2015-11-13 | You-Ping Chan | ANALOGUE OF INSULIN GLARGINE |
| WO2015086728A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Exendin-4 peptide analogues as dual glp-1/gip receptor agonists |
| EP3080149A1 (en) | 2013-12-13 | 2016-10-19 | Sanofi | Dual glp-1/glucagon receptor agonists |
| TW201609799A (en) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | Dual GLP-1/GIP receptor agonists |
| WO2015086730A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Non-acylated exendin-4 peptide analogues |
| JP2017509603A (en) | 2014-02-18 | 2017-04-06 | ノヴォ ノルディスク アー／エス | Stable glucagon analogues and uses for the treatment of hypoglycemia |
| AR099569A1 (en) | 2014-02-28 | 2016-08-03 | Novo Nordisk As | INSULIN DERIVATIVES AND THE MEDICAL USES OF THESE |
| TW201625669A (en) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | Peptidic dual GLP-1/glucagon receptor agonists derived from Exendin-4 |
| TW201625670A (en) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | Dual GLP-1/glucagon receptor agonists derived from EXENDIN-4 |
| TW201625668A (en) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | Exendin-4 derivatives as peptidic dual GLP-1/glucagon receptor agonists |
| EP3151852A1 (en) | 2014-06-04 | 2017-04-12 | Novo Nordisk A/S | Glp-1/glucagon receptor co-agonists for medical use |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| AR105319A1 (en) | 2015-06-05 | 2017-09-27 | Sanofi Sa | PROPHARMS THAT INCLUDE A DUAL AGONIST GLU-1 / GLUCAGON CONJUGATE HIALURONIC ACID CONNECTOR |
| TW201706291A (en) | 2015-07-10 | 2017-02-16 | 賽諾菲公司 | New EXENDIN-4 derivatives as selective peptidic dual GLP-1/glucagon receptor agonists |
| US20190010206A1 (en) | 2015-08-25 | 2019-01-10 | Novo Nordisk A/S | Novel Insulin Derivatives and the Medical Uses Hereof |
| WO2017032797A1 (en) | 2015-08-25 | 2017-03-02 | Novo Nordisk A/S | Novel insulin derivatives and the medical uses hereof |
| JP7432361B2 (en) * | 2016-08-02 | 2024-02-16 | 江蘇恒瑞医薬股▲ふん▼有限公司 | Acylated derivatives of human insulin or its analogs |
| WO2018096164A1 (en) | 2016-11-28 | 2018-05-31 | Novo Nordisk A/S | Insulin degludec for treating diabetes |
| WO2018096162A1 (en) | 2016-11-28 | 2018-05-31 | Novo Nordisk A/S | Insulin degludec in cardiovascular conditions |
| US11673933B2 (en) | 2016-11-28 | 2023-06-13 | Novo Nordisk A/S | Method for using insulin degludec for the improvement of glycemic control and reduction of acute and long-term diabetes complications |
| HUE055231T2 (en) | 2016-12-16 | 2021-11-29 | Novo Nordisk As | Insulin containing pharmaceutical compositions |
| JOP20190273A1 (en) * | 2017-05-26 | 2019-11-24 | Lilly Co Eli | Acylated insulin compound |
| KR20200119237A (en) | 2018-02-09 | 2020-10-19 | 지앙수 헨그루이 메디슨 컴퍼니 리미티드 | Codon-optimized precursor gene and signal peptide gene of human insulin analogue |
| JP2021524464A (en) | 2018-05-24 | 2021-09-13 | 江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司Ｊｉａｎｇｓｕ Ｈｅｎｇｒｕｉ Ｍｅｄｉｃｉｎｅ Ｃｏ．， Ｌｔｄ． | Method for preparing recombinant human insulin or its analog precursor |
| JP7410891B2 (en) | 2018-06-26 | 2024-01-10 | ノボ・ノルデイスク・エー／エス | System providing dosing recommendations for basal insulin titration |
| US10335464B1 (en) | 2018-06-26 | 2019-07-02 | Novo Nordisk A/S | Device for titrating basal insulin |
| KR102666154B1 (en) | 2018-08-08 | 2024-05-20 | 주식회사 대웅제약 | Long-acting Insulin Analog and Derivatives Thereof |
| KR20200080747A (en) | 2018-12-27 | 2020-07-07 | 주식회사 폴루스 | An Enzymatic Conversion Composition for Producing Insulin from Proinsulin and a Method for Producing Insulin from Proinsulin Using the Same |
| KR20200080748A (en) | 2018-12-27 | 2020-07-07 | 주식회사 폴루스 | A Method for Purifying Proinsulin Using Anion Exchange Chromatography |
| AU2020321977C1 (en) | 2019-07-31 | 2024-04-18 | Eli Lilly And Company | Relaxin analogs and methods of using the same |
| KR20220121833A (en) | 2019-12-30 | 2022-09-01 | 간 앤 리 파마슈티칼스 컴퍼니, 리미티드 | insulin derivatives |
| EP4299057A1 (en) | 2022-06-30 | 2024-01-03 | Adocia | Solid compositions comprising a peptide or a protein and an acylated amino acid |
| EP4180060A1 (en) | 2021-11-15 | 2023-05-17 | Adocia | Solid compositions comprising a peptide or a protein and an acylated amino acid |
| WO2023084118A1 (en) | 2021-11-15 | 2023-05-19 | Adocia | Solid compositions comprising a peptide or a protein and an acylated amino acid |
| EP4299071A1 (en) | 2022-07-01 | 2024-01-03 | Adocia | Compositions comprising a peptide or a protein and an acylated amino acid |
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