FI99192B - Procedure for inactivation of viruses in blood and blood products - Google Patents
Procedure for inactivation of viruses in blood and blood productsInfo
- Publication number
- FI99192B FI99192B FI920981A FI920981A FI99192B FI 99192 B FI99192 B FI 99192B FI 920981 A FI920981 A FI 920981A FI 920981 A FI920981 A FI 920981A FI 99192 B FI99192 B FI 99192B
- Authority
- FI
- Finland
- Prior art keywords
- blood
- inactivation
- viruses
- procedure
- products
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/08—Radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0218—Multiple bag systems for separating or storing blood components with filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
- A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
- A61M1/3686—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents by removing photoactive agents after irradiation
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- External Artificial Organs (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
The invention relates to a process for the selective removal of photodynamic substances from blood and blood products, where the purification takes place on adsorbents. An arrangement which has proved particularly advantageous for this purpose is one in which the blood or the relevant blood fraction is passed over a separating column which contains the adsorbent.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3930510A DE3930510A1 (en) | 1989-09-13 | 1989-09-13 | PROCESS FOR INACTIVATING VIRUSES IN BLOOD AND BLOOD PRODUCTS |
DE3930510 | 1989-09-13 | ||
PCT/DE1990/000691 WO1991003933A1 (en) | 1989-09-13 | 1990-09-08 | Process for inactivating viruses in blood and blood products |
DE9000691 | 1990-09-08 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI920981A0 FI920981A0 (en) | 1992-03-05 |
FI99192B true FI99192B (en) | 1997-07-15 |
FI99192C FI99192C (en) | 1997-10-27 |
Family
ID=6389298
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI920981A FI99192C (en) | 1989-09-13 | 1992-03-05 | Procedure for inactivation of viruses in blood and blood products |
Country Status (14)
Country | Link |
---|---|
EP (2) | EP0593098A3 (en) |
JP (1) | JP2965695B2 (en) |
AT (1) | ATE161681T1 (en) |
AU (1) | AU635068B2 (en) |
CA (1) | CA2065842C (en) |
CS (1) | CS76692A3 (en) |
DE (3) | DE3930510A1 (en) |
DK (1) | DK0491757T4 (en) |
ES (1) | ES2113347T5 (en) |
FI (1) | FI99192C (en) |
HU (1) | HU215131B (en) |
NO (1) | NO300911B1 (en) |
RU (1) | RU2036235C1 (en) |
WO (1) | WO1991003933A1 (en) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5571666A (en) * | 1988-10-28 | 1996-11-05 | Oklahoma Medical Research Foundation | Thiazine dyes used to inactivate HIV in biological fluids |
US6348309B1 (en) * | 1989-09-13 | 2002-02-19 | Blutspendedienst Der Landesverbaende Des Deutschen Roten Kreuzes Niedersachsen, Oldenburg Und Bremen G.G.M.B.H. | Process for inactivating viruses in blood and blood products |
US6187572B1 (en) | 1990-04-16 | 2001-02-13 | Baxter International Inc. | Method of inactivation of viral and bacterial blood contaminants |
US6251644B1 (en) | 1990-04-16 | 2001-06-26 | Baxter International, Inc. | Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer |
US5120649A (en) * | 1990-05-15 | 1992-06-09 | New York Blood Center, Inc. | Photodynamic inactivation of viruses in blood cell-containing compositions |
DE9102709U1 (en) * | 1991-03-07 | 1991-05-23 | Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Oldenburg und Bremen Gemeinnützige GmbH, 3257 Springe | Blood bag arrangement |
US6433343B1 (en) | 1992-03-02 | 2002-08-13 | Cerus Corporation | Device and method for photoactivation |
WO1996014740A1 (en) | 1992-03-02 | 1996-05-23 | Cerus Corporation | Synthetic media for blood components |
US6207107B1 (en) * | 1992-10-05 | 2001-03-27 | Baxter International Inc. | Steam sterilizable system for inactivating viral contaminants in body fluids |
ZA944488B (en) * | 1993-06-23 | 1995-02-15 | New York Blood Center Inc | System for viral inactivation of blood |
US6420570B1 (en) | 1993-06-28 | 2002-07-16 | Cerus Corporation | Psoralen compounds |
US5399719A (en) | 1993-06-28 | 1995-03-21 | Steritech, Inc. | Compounds for the photodecontamination of pathogens in blood |
US5556993A (en) | 1993-06-28 | 1996-09-17 | Steritech, Inc. | Compounds for the photodecontamination of pathogens in blood |
US6319662B1 (en) * | 1993-12-17 | 2001-11-20 | Baxter International Inc. | Method and apparatus for removing viral contaminants from a body fluid |
US5639376A (en) * | 1994-01-10 | 1997-06-17 | Hemasure, Inc. | Process for simultaneously removing leukocytes and methylene blue from plasma |
WO1995018665A1 (en) * | 1994-01-10 | 1995-07-13 | Hemasure, Inc. | Device and process for removing leukocytes and viral inactivating agents from blood |
DE4444045C2 (en) * | 1994-12-10 | 1997-04-17 | Behringwerke Ag | Method for inactivating viruses using acridine or acridine derivatives |
US6544727B1 (en) | 1995-06-07 | 2003-04-08 | Cerus Corporation | Methods and devices for the removal of psoralens from blood products |
AT406778B (en) * | 1996-04-09 | 2000-09-25 | Immuno Ag | METHOD FOR DISINEGRATING NUCLEIC ACIDS AND PRODUCING QUALITY-ASSURED BIOLOGICAL PRODUCTS |
US6638772B1 (en) * | 1996-06-17 | 2003-10-28 | Amire Medical | Electrochemical test device |
US5922278A (en) * | 1996-11-19 | 1999-07-13 | Baxter International Inc. | Method and apparatus for inactivating contaminants in biological fluid |
US6190609B1 (en) | 1996-11-19 | 2001-02-20 | Baxter International Inc. | Methods and apparatus for inactivating contaminants in biological fluid |
US20010009756A1 (en) | 1998-01-06 | 2001-07-26 | Derek Hei | Flow devices for the reduction of compounds from biological compositions and methods of use |
US20010018179A1 (en) | 1998-01-06 | 2001-08-30 | Derek J. Hei | Batch devices for the reduction of compounds from biological compositions containing cells and methods of use |
DE69819360T2 (en) * | 1997-11-20 | 2004-08-19 | Cerus Corp., Concord | NEW PSORAL FOR INACTIVATION OF PATHOGENES |
US7611831B2 (en) | 1998-01-06 | 2009-11-03 | Cerus Corporation | Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix |
US6610436B1 (en) | 1998-09-11 | 2003-08-26 | Gore Enterprise Holdings | Catalytic coatings and fuel cell electrodes and membrane electrode assemblies made therefrom |
DE19904088A1 (en) * | 1999-02-02 | 2000-09-07 | Fressenius Hemocare Gmbh | Tubing set for a cell separator for separating blood into its components and method for separating blood into its components |
DE19914850A1 (en) * | 1999-04-01 | 2000-10-05 | Gerhard Saalmann | Device for inactivating viruses, especially human immunodeficiency virus (HIV) from blood products, uses coloring agents and radiation |
US6565802B1 (en) | 1999-06-03 | 2003-05-20 | Baxter International Inc. | Apparatus, systems and methods for processing and treating a biological fluid with light |
US6268120B1 (en) | 1999-10-19 | 2001-07-31 | Gambro, Inc. | Isoalloxazine derivatives to neutralize biological contaminants |
TW590780B (en) | 2000-06-02 | 2004-06-11 | Gambro Inc | Additive solutions containing riboflavin |
US7648699B2 (en) | 2000-06-02 | 2010-01-19 | Caridianbct Biotechnologies, Llc | Preventing transfusion related complications in a recipient of a blood transfusion |
US7985588B2 (en) | 2000-06-02 | 2011-07-26 | Caridianbct Biotechnologies, Llc | Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light |
US9044523B2 (en) | 2000-06-15 | 2015-06-02 | Terumo Bct, Inc. | Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light |
DE10031851B4 (en) * | 2000-07-04 | 2005-10-13 | Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Sachsen-Anhalt, Thüringen, Oldenburg und Bremen gGmbH | Photodynamic treatment and UV-B irradiation of a platelet suspension |
EP1469891B1 (en) * | 2002-02-01 | 2009-04-15 | CaridianBCT Biotechnologies, LLC | Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light |
EP3078740A4 (en) * | 2014-05-23 | 2017-08-23 | Mkrtchyan, Ovik Leonardovich | Method for inactivating, on medical instruments, viruses containing rna and dna, and apparatus for implementing same |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2827109C2 (en) * | 1977-06-24 | 1986-10-30 | Asahi Kasei Kogyo K.K., Osaka | Method and device for the separation of organic compounds from plasma proteins of the blood |
JPS5665071A (en) * | 1979-11-01 | 1981-06-02 | Asahi Chem Ind Co Ltd | Photo-oxidation treating agent |
US4727027A (en) * | 1983-05-02 | 1988-02-23 | Diamond Scientific Co. | Photochemical decontamination treatment of whole blood or blood components |
US4748120A (en) * | 1983-05-02 | 1988-05-31 | Diamond Scientific Co. | Photochemical decontamination treatment of whole blood or blood components |
JPS61275228A (en) † | 1985-03-14 | 1986-12-05 | バクスタ−、トラベノ−ル、ラボラトリ−ズ、インコ−ポレイテツド | Photodynamic inactivity of virus in therapeutical protein composition |
US4775625A (en) * | 1986-11-21 | 1988-10-04 | The Medical College Of Wisconsin, Inc. | Inactivating enveloped viruses with a merocyanine dye |
DE3717951C1 (en) * | 1987-05-25 | 1988-11-24 | Shanmugam Murugavel | Use of silica gel to detoxify blood |
US4878891A (en) * | 1987-06-25 | 1989-11-07 | Baylor Research Foundation | Method for eradicating infectious biological contaminants in body tissues |
DE3805459A1 (en) * | 1988-02-22 | 1989-08-31 | Biotest Pharma Gmbh | METHOD FOR STERILIZING BLOOD, PLASMA, BLOOD AND PLASMA DERIVATIVES, CELL SUSPENSIONS OR THE LIKE |
US5149718A (en) * | 1989-01-19 | 1992-09-22 | New York University | Biological fluid purification system |
EP0471794B1 (en) * | 1989-05-11 | 1996-10-02 | Oklahoma Medical Research Foundation | Antiviral therapy using thiazine and xanthene dyes |
-
1989
- 1989-09-13 DE DE3930510A patent/DE3930510A1/en not_active Withdrawn
-
1990
- 1990-09-08 JP JP2512344A patent/JP2965695B2/en not_active Expired - Fee Related
- 1990-09-08 AT AT90913337T patent/ATE161681T1/en not_active IP Right Cessation
- 1990-09-08 DE DE59010793T patent/DE59010793D1/en not_active Expired - Lifetime
- 1990-09-08 DK DK90913337T patent/DK0491757T4/en active
- 1990-09-08 DE DE122008000026C patent/DE122008000026I2/en active Active
- 1990-09-08 HU HU9200627A patent/HU215131B/en unknown
- 1990-09-08 EP EP19930120072 patent/EP0593098A3/en not_active Withdrawn
- 1990-09-08 ES ES90913337T patent/ES2113347T5/en not_active Expired - Lifetime
- 1990-09-08 CA CA002065842A patent/CA2065842C/en not_active Expired - Lifetime
- 1990-09-08 WO PCT/DE1990/000691 patent/WO1991003933A1/en active IP Right Grant
- 1990-09-08 EP EP90913337A patent/EP0491757B2/en not_active Expired - Lifetime
- 1990-09-08 AU AU63391/90A patent/AU635068B2/en not_active Expired
-
1992
- 1992-03-03 NO NO920834A patent/NO300911B1/en not_active IP Right Cessation
- 1992-03-05 FI FI920981A patent/FI99192C/en active
- 1992-03-12 RU SU925011884A patent/RU2036235C1/en active
- 1992-03-13 CS CS92766A patent/CS76692A3/en unknown
Also Published As
Publication number | Publication date |
---|---|
ATE161681T1 (en) | 1998-01-15 |
CA2065842A1 (en) | 1991-03-14 |
NO920834L (en) | 1992-03-03 |
FI920981A0 (en) | 1992-03-05 |
HU215131B (en) | 1998-09-28 |
EP0491757B1 (en) | 1998-01-07 |
FI99192C (en) | 1997-10-27 |
AU635068B2 (en) | 1993-03-11 |
CA2065842C (en) | 1999-12-21 |
ES2113347T5 (en) | 2002-09-16 |
AU6339190A (en) | 1991-04-18 |
DK0491757T3 (en) | 1998-09-07 |
EP0593098A2 (en) | 1994-04-20 |
EP0593098A3 (en) | 1994-04-27 |
HU9200627D0 (en) | 1992-05-28 |
WO1991003933A1 (en) | 1991-04-04 |
DE59010793D1 (en) | 1998-02-12 |
ES2113347T3 (en) | 1998-05-01 |
JPH05500366A (en) | 1993-01-28 |
EP0491757A1 (en) | 1992-07-01 |
DE3930510A1 (en) | 1991-03-21 |
NO300911B1 (en) | 1997-08-18 |
DE122008000026I2 (en) | 2011-05-05 |
EP0491757B2 (en) | 2002-01-09 |
RU2036235C1 (en) | 1995-05-27 |
DE122008000026I1 (en) | 2008-08-21 |
HUT60142A (en) | 1992-08-28 |
CS76692A3 (en) | 1992-08-12 |
JP2965695B2 (en) | 1999-10-18 |
NO920834D0 (en) | 1992-03-03 |
DK0491757T4 (en) | 2002-04-22 |
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Legal Events
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