CS76692A3 - Process of the inactivation of viruses in blood and blood products - Google Patents
Process of the inactivation of viruses in blood and blood productsInfo
- Publication number
- CS76692A3 CS76692A3 CS92766A CS76692A CS76692A3 CS 76692 A3 CS76692 A3 CS 76692A3 CS 92766 A CS92766 A CS 92766A CS 76692 A CS76692 A CS 76692A CS 76692 A3 CS76692 A3 CS 76692A3
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- blood
- inactivation
- viruses
- products
- blood products
- Prior art date
Links
- 239000010836 blood and blood product Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 241000700605 Viruses Species 0.000 title 1
- 230000002779 inactivation Effects 0.000 title 1
- 239000003463 adsorbent Substances 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 2
- 238000000746 purification Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/08—Radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0218—Multiple bag systems for separating or storing blood components with filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
- A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
- A61M1/3686—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents by removing photoactive agents after irradiation
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- External Artificial Organs (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
The invention relates to a process for the selective removal of photodynamic substances from blood and blood products, where the purification takes place on adsorbents. An arrangement which has proved particularly advantageous for this purpose is one in which the blood or the relevant blood fraction is passed over a separating column which contains the adsorbent.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3930510A DE3930510A1 (en) | 1989-09-13 | 1989-09-13 | PROCESS FOR INACTIVATING VIRUSES IN BLOOD AND BLOOD PRODUCTS |
PCT/DE1990/000691 WO1991003933A1 (en) | 1989-09-13 | 1990-09-08 | Process for inactivating viruses in blood and blood products |
Publications (1)
Publication Number | Publication Date |
---|---|
CS76692A3 true CS76692A3 (en) | 1992-08-12 |
Family
ID=6389298
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS92766A CS76692A3 (en) | 1989-09-13 | 1992-03-13 | Process of the inactivation of viruses in blood and blood products |
Country Status (14)
Country | Link |
---|---|
EP (2) | EP0593098A3 (en) |
JP (1) | JP2965695B2 (en) |
AT (1) | ATE161681T1 (en) |
AU (1) | AU635068B2 (en) |
CA (1) | CA2065842C (en) |
CS (1) | CS76692A3 (en) |
DE (3) | DE3930510A1 (en) |
DK (1) | DK0491757T4 (en) |
ES (1) | ES2113347T5 (en) |
FI (1) | FI99192C (en) |
HU (1) | HU215131B (en) |
NO (1) | NO300911B1 (en) |
RU (1) | RU2036235C1 (en) |
WO (1) | WO1991003933A1 (en) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5571666A (en) * | 1988-10-28 | 1996-11-05 | Oklahoma Medical Research Foundation | Thiazine dyes used to inactivate HIV in biological fluids |
US6348309B1 (en) * | 1989-09-13 | 2002-02-19 | Blutspendedienst Der Landesverbaende Des Deutschen Roten Kreuzes Niedersachsen, Oldenburg Und Bremen G.G.M.B.H. | Process for inactivating viruses in blood and blood products |
US6187572B1 (en) | 1990-04-16 | 2001-02-13 | Baxter International Inc. | Method of inactivation of viral and bacterial blood contaminants |
US6251644B1 (en) | 1990-04-16 | 2001-06-26 | Baxter International, Inc. | Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer |
US5120649A (en) * | 1990-05-15 | 1992-06-09 | New York Blood Center, Inc. | Photodynamic inactivation of viruses in blood cell-containing compositions |
DE9102709U1 (en) * | 1991-03-07 | 1991-05-23 | Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Oldenburg und Bremen Gemeinnützige GmbH, 3257 Springe | Blood bag arrangement |
AU4107396A (en) | 1992-03-02 | 1996-06-06 | Cerus Corporation | Synthetic media for blood components |
US6433343B1 (en) | 1992-03-02 | 2002-08-13 | Cerus Corporation | Device and method for photoactivation |
US6207107B1 (en) * | 1992-10-05 | 2001-03-27 | Baxter International Inc. | Steam sterilizable system for inactivating viral contaminants in body fluids |
EP0707633A4 (en) * | 1993-06-23 | 1996-08-14 | New York Blood Center Inc | SYSTEM FOR VIRAL INACTIVATION OF BLOOD |
US5712085A (en) | 1993-06-28 | 1998-01-27 | Cerus Corporation | 5'-(4-amino-2-oxa)butye-4,4', 8-trinethylpsoralen in synthetic medium |
US5399719A (en) | 1993-06-28 | 1995-03-21 | Steritech, Inc. | Compounds for the photodecontamination of pathogens in blood |
US6420570B1 (en) | 1993-06-28 | 2002-07-16 | Cerus Corporation | Psoralen compounds |
US6319662B1 (en) * | 1993-12-17 | 2001-11-20 | Baxter International Inc. | Method and apparatus for removing viral contaminants from a body fluid |
US5639376A (en) * | 1994-01-10 | 1997-06-17 | Hemasure, Inc. | Process for simultaneously removing leukocytes and methylene blue from plasma |
CA2180328A1 (en) * | 1994-01-10 | 1995-07-13 | Franco Castino | Device and process for removing leukocytes and viral inactivating agents from blood |
DE4444045C2 (en) * | 1994-12-10 | 1997-04-17 | Behringwerke Ag | Method for inactivating viruses using acridine or acridine derivatives |
US6544727B1 (en) | 1995-06-07 | 2003-04-08 | Cerus Corporation | Methods and devices for the removal of psoralens from blood products |
AT406778B (en) * | 1996-04-09 | 2000-09-25 | Immuno Ag | METHOD FOR DISINEGRATING NUCLEIC ACIDS AND PRODUCING QUALITY-ASSURED BIOLOGICAL PRODUCTS |
JP2000512762A (en) * | 1996-06-17 | 2000-09-26 | マーキュリー ダイアグノスティックス インコーポレイテッド | Electrochemical test equipment and related methods |
US5922278A (en) * | 1996-11-19 | 1999-07-13 | Baxter International Inc. | Method and apparatus for inactivating contaminants in biological fluid |
US6190609B1 (en) | 1996-11-19 | 2001-02-20 | Baxter International Inc. | Methods and apparatus for inactivating contaminants in biological fluid |
US20010018179A1 (en) | 1998-01-06 | 2001-08-30 | Derek J. Hei | Batch devices for the reduction of compounds from biological compositions containing cells and methods of use |
US20010009756A1 (en) | 1998-01-06 | 2001-07-26 | Derek Hei | Flow devices for the reduction of compounds from biological compositions and methods of use |
ATE252830T1 (en) * | 1997-11-20 | 2003-11-15 | Cerus Corp | NEW PSORALENES FOR INACTIVATION OF PATHOGENS |
US7611831B2 (en) | 1998-01-06 | 2009-11-03 | Cerus Corporation | Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix |
US7049110B2 (en) | 1998-07-21 | 2006-05-23 | Gambro, Inc. | Inactivation of West Nile virus and malaria using photosensitizers |
US7498156B2 (en) | 1998-07-21 | 2009-03-03 | Caridianbct Biotechnologies, Llc | Use of visible light at wavelengths of 500 to 550 nm to reduce the number of pathogens in blood and blood components |
US6610436B1 (en) | 1998-09-11 | 2003-08-26 | Gore Enterprise Holdings | Catalytic coatings and fuel cell electrodes and membrane electrode assemblies made therefrom |
DE19904088A1 (en) * | 1999-02-02 | 2000-09-07 | Fressenius Hemocare Gmbh | Tubing set for a cell separator for separating blood into its components and method for separating blood into its components |
DE19914850A1 (en) * | 1999-04-01 | 2000-10-05 | Gerhard Saalmann | Device for inactivating viruses, especially human immunodeficiency virus (HIV) from blood products, uses coloring agents and radiation |
US7025877B1 (en) | 1999-06-03 | 2006-04-11 | Baxter International Inc. | Processing set for processing and treating a biological fluid |
US7445756B2 (en) | 1999-06-03 | 2008-11-04 | Fenwal, Inc. | Fluid processing sets and organizers for the same |
US7068361B2 (en) | 1999-06-03 | 2006-06-27 | Baxter International | Apparatus, systems and methods for processing and treating a biological fluid with light |
US6565802B1 (en) | 1999-06-03 | 2003-05-20 | Baxter International Inc. | Apparatus, systems and methods for processing and treating a biological fluid with light |
US7220747B2 (en) | 1999-07-20 | 2007-05-22 | Gambro, Inc. | Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer |
US7094378B1 (en) | 2000-06-15 | 2006-08-22 | Gambro, Inc. | Method and apparatus for inactivation of biological contaminants using photosensitizers |
RU2200009C2 (en) * | 1999-08-04 | 2003-03-10 | Григорьянц Рубен Исаакович | Method for treating the cases of acquired immune deficiency syndrome (aids) by applying photosensitization techniques |
US6268120B1 (en) | 1999-10-19 | 2001-07-31 | Gambro, Inc. | Isoalloxazine derivatives to neutralize biological contaminants |
US7985588B2 (en) | 2000-06-02 | 2011-07-26 | Caridianbct Biotechnologies, Llc | Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light |
TW590780B (en) | 2000-06-02 | 2004-06-11 | Gambro Inc | Additive solutions containing riboflavin |
US7648699B2 (en) | 2000-06-02 | 2010-01-19 | Caridianbct Biotechnologies, Llc | Preventing transfusion related complications in a recipient of a blood transfusion |
US9044523B2 (en) | 2000-06-15 | 2015-06-02 | Terumo Bct, Inc. | Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light |
DE10031851B4 (en) * | 2000-07-04 | 2005-10-13 | Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Sachsen-Anhalt, Thüringen, Oldenburg und Bremen gGmbH | Photodynamic treatment and UV-B irradiation of a platelet suspension |
CA2474242C (en) * | 2002-02-01 | 2011-05-17 | Gambro, Inc. | Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light |
RU2223124C1 (en) * | 2003-03-20 | 2004-02-10 | Федченко Петр Петрович | Method for inactivating aids virus |
RU2357770C1 (en) * | 2007-09-27 | 2009-06-10 | Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") | Method of photo inactivation of bird influenza a virus of subtype h5n1 |
EA032842B1 (en) * | 2014-05-23 | 2019-07-31 | Овик Леонардович МКРТЧЯН | Method for inactivating, on medical instruments, viruses containing rna and dna, and apparatus for implementing same |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2827109C2 (en) * | 1977-06-24 | 1986-10-30 | Asahi Kasei Kogyo K.K., Osaka | Method and device for the separation of organic compounds from plasma proteins of the blood |
JPS5665071A (en) * | 1979-11-01 | 1981-06-02 | Asahi Chem Ind Co Ltd | Photo-oxidation treating agent |
US4727027A (en) * | 1983-05-02 | 1988-02-23 | Diamond Scientific Co. | Photochemical decontamination treatment of whole blood or blood components |
US4748120A (en) * | 1983-05-02 | 1988-05-31 | Diamond Scientific Co. | Photochemical decontamination treatment of whole blood or blood components |
JPS61275228A (en) * | 1985-03-14 | 1986-12-05 | バクスタ−、トラベノ−ル、ラボラトリ−ズ、インコ−ポレイテツド | Photodynamic inactivity of virus in therapeutical protein composition |
US4775625A (en) * | 1986-11-21 | 1988-10-04 | The Medical College Of Wisconsin, Inc. | Inactivating enveloped viruses with a merocyanine dye |
DE3717951C1 (en) * | 1987-05-25 | 1988-11-24 | Shanmugam Murugavel | Use of silica gel to detoxify blood |
US4878891A (en) * | 1987-06-25 | 1989-11-07 | Baylor Research Foundation | Method for eradicating infectious biological contaminants in body tissues |
DE3805459A1 (en) * | 1988-02-22 | 1989-08-31 | Biotest Pharma Gmbh | METHOD FOR STERILIZING BLOOD, PLASMA, BLOOD AND PLASMA DERIVATIVES, CELL SUSPENSIONS OR THE LIKE |
US5149718A (en) * | 1989-01-19 | 1992-09-22 | New York University | Biological fluid purification system |
DK0471794T3 (en) * | 1989-05-11 | 1996-11-18 | Oklahoma Med Res Found | Antiviral therapy using thiazine and xanthene dyes |
-
1989
- 1989-09-13 DE DE3930510A patent/DE3930510A1/en not_active Withdrawn
-
1990
- 1990-09-08 AT AT90913337T patent/ATE161681T1/en not_active IP Right Cessation
- 1990-09-08 AU AU63391/90A patent/AU635068B2/en not_active Expired
- 1990-09-08 HU HU9200627A patent/HU215131B/en unknown
- 1990-09-08 EP EP19930120072 patent/EP0593098A3/en not_active Withdrawn
- 1990-09-08 WO PCT/DE1990/000691 patent/WO1991003933A1/en active IP Right Grant
- 1990-09-08 JP JP2512344A patent/JP2965695B2/en not_active Expired - Fee Related
- 1990-09-08 ES ES90913337T patent/ES2113347T5/en not_active Expired - Lifetime
- 1990-09-08 EP EP90913337A patent/EP0491757B2/en not_active Expired - Lifetime
- 1990-09-08 DE DE59010793T patent/DE59010793D1/en not_active Expired - Lifetime
- 1990-09-08 DK DK90913337T patent/DK0491757T4/en active
- 1990-09-08 DE DE122008000026C patent/DE122008000026I2/en active Active
- 1990-09-08 CA CA002065842A patent/CA2065842C/en not_active Expired - Lifetime
-
1992
- 1992-03-03 NO NO920834A patent/NO300911B1/en not_active IP Right Cessation
- 1992-03-05 FI FI920981A patent/FI99192C/en active
- 1992-03-12 RU SU925011884A patent/RU2036235C1/en active
- 1992-03-13 CS CS92766A patent/CS76692A3/en unknown
Also Published As
Publication number | Publication date |
---|---|
NO920834L (en) | 1992-03-03 |
DK0491757T4 (en) | 2002-04-22 |
AU635068B2 (en) | 1993-03-11 |
RU2036235C1 (en) | 1995-05-27 |
FI920981A0 (en) | 1992-03-05 |
FI99192B (en) | 1997-07-15 |
DE3930510A1 (en) | 1991-03-21 |
EP0593098A3 (en) | 1994-04-27 |
EP0491757B1 (en) | 1998-01-07 |
EP0593098A2 (en) | 1994-04-20 |
HU215131B (en) | 1998-09-28 |
ES2113347T5 (en) | 2002-09-16 |
HU9200627D0 (en) | 1992-05-28 |
NO300911B1 (en) | 1997-08-18 |
EP0491757A1 (en) | 1992-07-01 |
AU6339190A (en) | 1991-04-18 |
ES2113347T3 (en) | 1998-05-01 |
DE122008000026I2 (en) | 2011-05-05 |
DK0491757T3 (en) | 1998-09-07 |
NO920834D0 (en) | 1992-03-03 |
DE122008000026I1 (en) | 2008-08-21 |
HUT60142A (en) | 1992-08-28 |
EP0491757B2 (en) | 2002-01-09 |
JPH05500366A (en) | 1993-01-28 |
WO1991003933A1 (en) | 1991-04-04 |
FI99192C (en) | 1997-10-27 |
ATE161681T1 (en) | 1998-01-15 |
DE59010793D1 (en) | 1998-02-12 |
CA2065842C (en) | 1999-12-21 |
CA2065842A1 (en) | 1991-03-14 |
JP2965695B2 (en) | 1999-10-18 |
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