CS76692A3 - Process of the inactivation of viruses in blood and blood products - Google Patents

Process of the inactivation of viruses in blood and blood products

Info

Publication number
CS76692A3
CS76692A3 CS92766A CS76692A CS76692A3 CS 76692 A3 CS76692 A3 CS 76692A3 CS 92766 A CS92766 A CS 92766A CS 76692 A CS76692 A CS 76692A CS 76692 A3 CS76692 A3 CS 76692A3
Authority
CS
Czechoslovakia
Prior art keywords
blood
inactivation
viruses
products
blood products
Prior art date
Application number
CS92766A
Other languages
Czech (cs)
Inventor
Harald Mohr
Bernd Lambrecht
Original Assignee
Blutspendedienst Dt Rote Kreuz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6389298&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CS76692(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Blutspendedienst Dt Rote Kreuz filed Critical Blutspendedienst Dt Rote Kreuz
Publication of CS76692A3 publication Critical patent/CS76692A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08—Radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0218—Multiple bag systems for separating or storing blood components with filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • A61M1/3686—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents by removing photoactive agents after irradiation

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

The invention relates to a process for the selective removal of photodynamic substances from blood and blood products, where the purification takes place on adsorbents. An arrangement which has proved particularly advantageous for this purpose is one in which the blood or the relevant blood fraction is passed over a separating column which contains the adsorbent.
CS92766A 1989-09-13 1992-03-13 Process of the inactivation of viruses in blood and blood products CS76692A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3930510A DE3930510A1 (en) 1989-09-13 1989-09-13 PROCESS FOR INACTIVATING VIRUSES IN BLOOD AND BLOOD PRODUCTS
PCT/DE1990/000691 WO1991003933A1 (en) 1989-09-13 1990-09-08 Process for inactivating viruses in blood and blood products

Publications (1)

Publication Number Publication Date
CS76692A3 true CS76692A3 (en) 1992-08-12

Family

ID=6389298

Family Applications (1)

Application Number Title Priority Date Filing Date
CS92766A CS76692A3 (en) 1989-09-13 1992-03-13 Process of the inactivation of viruses in blood and blood products

Country Status (14)

Country Link
EP (2) EP0491757B2 (en)
JP (1) JP2965695B2 (en)
AT (1) ATE161681T1 (en)
AU (1) AU635068B2 (en)
CA (1) CA2065842C (en)
CS (1) CS76692A3 (en)
DE (3) DE3930510A1 (en)
DK (1) DK0491757T4 (en)
ES (1) ES2113347T5 (en)
FI (1) FI99192C (en)
HU (1) HU215131B (en)
NO (1) NO300911B1 (en)
RU (1) RU2036235C1 (en)
WO (1) WO1991003933A1 (en)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571666A (en) * 1988-10-28 1996-11-05 Oklahoma Medical Research Foundation Thiazine dyes used to inactivate HIV in biological fluids
US6348309B1 (en) * 1989-09-13 2002-02-19 Blutspendedienst Der Landesverbaende Des Deutschen Roten Kreuzes Niedersachsen, Oldenburg Und Bremen G.G.M.B.H. Process for inactivating viruses in blood and blood products
US6187572B1 (en) 1990-04-16 2001-02-13 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
US6251644B1 (en) 1990-04-16 2001-06-26 Baxter International, Inc. Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer
US5120649A (en) * 1990-05-15 1992-06-09 New York Blood Center, Inc. Photodynamic inactivation of viruses in blood cell-containing compositions
DE9102709U1 (en) * 1991-03-07 1991-05-23 Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Oldenburg und Bremen Gemeinnützige GmbH, 3257 Springe Blood bag arrangement
US6433343B1 (en) 1992-03-02 2002-08-13 Cerus Corporation Device and method for photoactivation
WO1996014740A1 (en) 1992-03-02 1996-05-23 Cerus Corporation Synthetic media for blood components
US6207107B1 (en) * 1992-10-05 2001-03-27 Baxter International Inc. Steam sterilizable system for inactivating viral contaminants in body fluids
WO1995000631A1 (en) * 1993-06-23 1995-01-05 New York Blood Center, Inc. System for viral inactivation of blood
US5712085A (en) 1993-06-28 1998-01-27 Cerus Corporation 5'-(4-amino-2-oxa)butye-4,4', 8-trinethylpsoralen in synthetic medium
US6420570B1 (en) 1993-06-28 2002-07-16 Cerus Corporation Psoralen compounds
US5399719A (en) 1993-06-28 1995-03-21 Steritech, Inc. Compounds for the photodecontamination of pathogens in blood
US6319662B1 (en) * 1993-12-17 2001-11-20 Baxter International Inc. Method and apparatus for removing viral contaminants from a body fluid
US5639376A (en) * 1994-01-10 1997-06-17 Hemasure, Inc. Process for simultaneously removing leukocytes and methylene blue from plasma
AU1601595A (en) * 1994-01-10 1995-08-01 Hemasure, Inc. Device and process for removing leukocytes and viral inactivating agents from blood
DE4444045C2 (en) * 1994-12-10 1997-04-17 Behringwerke Ag Method for inactivating viruses using acridine or acridine derivatives
US6544727B1 (en) 1995-06-07 2003-04-08 Cerus Corporation Methods and devices for the removal of psoralens from blood products
AT406778B (en) * 1996-04-09 2000-09-25 Immuno Ag METHOD FOR DISINEGRATING NUCLEIC ACIDS AND PRODUCING QUALITY-ASSURED BIOLOGICAL PRODUCTS
WO1997048979A1 (en) * 1996-06-17 1997-12-24 Mercury Diagnostics Inc. Electrochemical test device and related methods
US6190609B1 (en) 1996-11-19 2001-02-20 Baxter International Inc. Methods and apparatus for inactivating contaminants in biological fluid
US5922278A (en) * 1996-11-19 1999-07-13 Baxter International Inc. Method and apparatus for inactivating contaminants in biological fluid
US20010018179A1 (en) 1998-01-06 2001-08-30 Derek J. Hei Batch devices for the reduction of compounds from biological compositions containing cells and methods of use
US20010009756A1 (en) 1998-01-06 2001-07-26 Derek Hei Flow devices for the reduction of compounds from biological compositions and methods of use
EP1032265B1 (en) 1997-11-20 2003-10-29 Cerus Corporation New psoralens for pathogen inactivation
US7611831B2 (en) 1998-01-06 2009-11-03 Cerus Corporation Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
US7049110B2 (en) 1998-07-21 2006-05-23 Gambro, Inc. Inactivation of West Nile virus and malaria using photosensitizers
US7498156B2 (en) 1998-07-21 2009-03-03 Caridianbct Biotechnologies, Llc Use of visible light at wavelengths of 500 to 550 nm to reduce the number of pathogens in blood and blood components
US6610436B1 (en) 1998-09-11 2003-08-26 Gore Enterprise Holdings Catalytic coatings and fuel cell electrodes and membrane electrode assemblies made therefrom
DE19904088A1 (en) * 1999-02-02 2000-09-07 Fressenius Hemocare Gmbh Tubing set for a cell separator for separating blood into its components and method for separating blood into its components
DE19914850A1 (en) * 1999-04-01 2000-10-05 Gerhard Saalmann Device for inactivating viruses, especially human immunodeficiency virus (HIV) from blood products, uses coloring agents and radiation
US7068361B2 (en) 1999-06-03 2006-06-27 Baxter International Apparatus, systems and methods for processing and treating a biological fluid with light
US7445756B2 (en) 1999-06-03 2008-11-04 Fenwal, Inc. Fluid processing sets and organizers for the same
US6565802B1 (en) 1999-06-03 2003-05-20 Baxter International Inc. Apparatus, systems and methods for processing and treating a biological fluid with light
US7025877B1 (en) 1999-06-03 2006-04-11 Baxter International Inc. Processing set for processing and treating a biological fluid
US7220747B2 (en) 1999-07-20 2007-05-22 Gambro, Inc. Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer
US7094378B1 (en) 2000-06-15 2006-08-22 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using photosensitizers
RU2200009C2 (en) * 1999-08-04 2003-03-10 Григорьянц Рубен Исаакович Method for treating the cases of acquired immune deficiency syndrome (aids) by applying photosensitization techniques
US6268120B1 (en) 1999-10-19 2001-07-31 Gambro, Inc. Isoalloxazine derivatives to neutralize biological contaminants
US7648699B2 (en) 2000-06-02 2010-01-19 Caridianbct Biotechnologies, Llc Preventing transfusion related complications in a recipient of a blood transfusion
US7985588B2 (en) 2000-06-02 2011-07-26 Caridianbct Biotechnologies, Llc Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light
TW590780B (en) 2000-06-02 2004-06-11 Gambro Inc Additive solutions containing riboflavin
US9044523B2 (en) 2000-06-15 2015-06-02 Terumo Bct, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
DE10031851B4 (en) * 2000-07-04 2005-10-13 Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Sachsen-Anhalt, Thüringen, Oldenburg und Bremen gGmbH Photodynamic treatment and UV-B irradiation of a platelet suspension
CA2474242C (en) * 2002-02-01 2011-05-17 Gambro, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
RU2223124C1 (en) * 2003-03-20 2004-02-10 Федченко Петр Петрович Method for inactivating aids virus
RU2357770C1 (en) * 2007-09-27 2009-06-10 Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") Method of photo inactivation of bird influenza a virus of subtype h5n1
CN110947012A (en) * 2014-05-23 2020-04-03 奥维克·莱昂纳多维奇·姆克尔强 Method for inactivating viruses comprising RNA and DNA on medical devices and apparatus for carrying out the method

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2827109C2 (en) * 1977-06-24 1986-10-30 Asahi Kasei Kogyo K.K., Osaka Method and device for the separation of organic compounds from plasma proteins of the blood
JPS5665071A (en) * 1979-11-01 1981-06-02 Asahi Chem Ind Co Ltd Photo-oxidation treating agent
US4748120A (en) * 1983-05-02 1988-05-31 Diamond Scientific Co. Photochemical decontamination treatment of whole blood or blood components
US4727027A (en) * 1983-05-02 1988-02-23 Diamond Scientific Co. Photochemical decontamination treatment of whole blood or blood components
JPS61275228A (en) † 1985-03-14 1986-12-05 バクスタ−、トラベノ−ル、ラボラトリ−ズ、インコ−ポレイテツド Photodynamic inactivity of virus in therapeutical protein composition
US4775625A (en) * 1986-11-21 1988-10-04 The Medical College Of Wisconsin, Inc. Inactivating enveloped viruses with a merocyanine dye
DE3717951C1 (en) * 1987-05-25 1988-11-24 Shanmugam Murugavel Use of silica gel to detoxify blood
US4878891A (en) * 1987-06-25 1989-11-07 Baylor Research Foundation Method for eradicating infectious biological contaminants in body tissues
DE3805459A1 (en) * 1988-02-22 1989-08-31 Biotest Pharma Gmbh METHOD FOR STERILIZING BLOOD, PLASMA, BLOOD AND PLASMA DERIVATIVES, CELL SUSPENSIONS OR THE LIKE
US5149718A (en) * 1989-01-19 1992-09-22 New York University Biological fluid purification system
DK0471794T3 (en) * 1989-05-11 1996-11-18 Oklahoma Med Res Found Antiviral therapy using thiazine and xanthene dyes

Also Published As

Publication number Publication date
EP0491757B1 (en) 1998-01-07
CA2065842A1 (en) 1991-03-14
CA2065842C (en) 1999-12-21
DK0491757T3 (en) 1998-09-07
DK0491757T4 (en) 2002-04-22
FI99192C (en) 1997-10-27
AU6339190A (en) 1991-04-18
EP0593098A2 (en) 1994-04-20
EP0491757B2 (en) 2002-01-09
JP2965695B2 (en) 1999-10-18
FI99192B (en) 1997-07-15
NO920834D0 (en) 1992-03-03
EP0593098A3 (en) 1994-04-27
DE3930510A1 (en) 1991-03-21
ES2113347T5 (en) 2002-09-16
AU635068B2 (en) 1993-03-11
EP0491757A1 (en) 1992-07-01
ATE161681T1 (en) 1998-01-15
DE122008000026I2 (en) 2011-05-05
WO1991003933A1 (en) 1991-04-04
ES2113347T3 (en) 1998-05-01
HUT60142A (en) 1992-08-28
DE122008000026I1 (en) 2008-08-21
RU2036235C1 (en) 1995-05-27
NO920834L (en) 1992-03-03
DE59010793D1 (en) 1998-02-12
JPH05500366A (en) 1993-01-28
HU215131B (en) 1998-09-28
FI920981A0 (en) 1992-03-05
NO300911B1 (en) 1997-08-18
HU9200627D0 (en) 1992-05-28

Similar Documents

Publication Publication Date Title
CS76692A3 (en) Process of the inactivation of viruses in blood and blood products
AU580402B2 (en) Method of inactivating viruses involving adsorption on solid phase
DE3379057D1 (en) Separation of mannose by selective adsorption on zeolitic molecular sieves
FR2667800B1 (en) ADSORPTION SEPARATION PROCESS, AND ADSORBER.
DE69111917D1 (en) Pressure swing adsorption process for the separation of gas mixtures.
DE3887312D1 (en) Spin-through adsorption process and gas separation system.
EP0630280A4 (en) Process and apparatus for removal of dna, viruses and endotoxins.
ES8608877A1 (en) Process and device for the selective separation of pathological and/or toxic species from blood or plasma with the use of filter candles.
DE3869301D1 (en) METHOD FOR PURIFYING GAS CONTAINING TOXIC COMPONENTS.
GB2337261B (en) Separation of nucleic acids
EP0168234A3 (en) Purification process for hepatitis surface antigen and product thereof
EP0416127A4 (en) Process for efficiently recovering adsorbable gas from gas which contains adsorbable gas at low concentration
AR244574A1 (en) Sorbent for the purification of polyolefins, and process for its manufacture
ES2105033T3 (en) PROTEIN PURIFICATION METHOD.
GR3004359T3 (en)
AU2140888A (en) Purification process
EP0603671A3 (en) Process of reactivating purified membrane proteins.
ATE155481T1 (en) METHOD FOR PURIFYING STREPTOLYSIN 0, INTACT STREPTOLYSIN 0 AVAILABLE BY THIS METHOD AND ITS USE
DE68918436D1 (en) Adsorptive separation process for the purification of 2,6-dimethylnaphthalene.
MX9700290A (en) Process for the removal of dissolved metallic catalyst from ester products.
FI891113A7 (en) DEVICE FOR GAS PURIFICATION.