FI972763L - Mutanttiproteiineja - Google Patents

Mutanttiproteiineja Download PDF

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Publication number
FI972763L
FI972763L FI972763A FI972763A FI972763L FI 972763 L FI972763 L FI 972763L FI 972763 A FI972763 A FI 972763A FI 972763 A FI972763 A FI 972763A FI 972763 L FI972763 L FI 972763L
Authority
FI
Finland
Prior art keywords
mutant proteins
mutant
proteins
Prior art date
Application number
FI972763A
Other languages
English (en)
Swedish (sv)
Other versions
FI972763A7 (fi
FI972763A0 (fi
Inventor
Joachim Hauber
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9502771.0A external-priority patent/GB9502771D0/en
Priority claimed from GBGB9513505.9A external-priority patent/GB9513505D0/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI972763A0 publication Critical patent/FI972763A0/fi
Publication of FI972763A7 publication Critical patent/FI972763A7/fi
Publication of FI972763L publication Critical patent/FI972763L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
FI972763A 1995-02-13 1996-02-12 Mutanttiproteiineja FI972763L (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9502771.0A GB9502771D0 (en) 1995-02-13 1995-02-13 Organic compounds
GBGB9513505.9A GB9513505D0 (en) 1995-07-03 1995-07-03 Organic compounds
PCT/EP1996/000585 WO1996025492A1 (en) 1995-02-13 1996-02-12 EUKARYOTIC INITIATION FACTOR 5A (eIF-5A) MUTANTS

Publications (3)

Publication Number Publication Date
FI972763A0 FI972763A0 (fi) 1997-06-26
FI972763A7 FI972763A7 (fi) 1997-10-10
FI972763L true FI972763L (fi) 1997-10-10

Family

ID=26306494

Family Applications (1)

Application Number Title Priority Date Filing Date
FI972763A FI972763L (fi) 1995-02-13 1996-02-12 Mutanttiproteiineja

Country Status (15)

Country Link
EP (1) EP0811060A1 (fi)
JP (1) JPH10509327A (fi)
KR (1) KR19980702160A (fi)
CN (1) CN1173897A (fi)
AU (1) AU4665196A (fi)
BR (1) BR9606951A (fi)
CA (1) CA2210538A1 (fi)
CZ (1) CZ255397A3 (fi)
FI (1) FI972763L (fi)
HU (1) HUP9801681A3 (fi)
IL (1) IL117113A0 (fi)
NO (1) NO973679L (fi)
PL (1) PL321239A1 (fi)
SK (1) SK109997A3 (fi)
WO (1) WO1996025492A1 (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6448040B1 (en) * 1997-06-20 2002-09-10 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Inhibitor of cellular proliferation
US7166467B2 (en) 2001-07-23 2007-01-23 Senesco Technologies, Inc. Nucleic acids, polypeptides, compositions, and methods for modulating apoptosis
US7968523B2 (en) * 2001-07-23 2011-06-28 Senesco Technologies, Inc. Method for inducing apoptosis using apoptosis-specific EIF5-A
US7217517B2 (en) * 2001-07-23 2007-05-15 Senesco Technologies, Inc. Nucleic acids, polypeptides, and methods for modulating apoptosis
US6867237B1 (en) * 2001-07-23 2005-03-15 Senesco Technologies, Inc. DNA encoding apoptosis-induced eucaryotic initiation factor-5A and deoxyhypusine synthase and a method for controlling apoptosis in animals and humans
US7381708B2 (en) 2001-07-23 2008-06-03 Sensco Technologies, Inc. Suppression of eIF5A1 expression by the use of antisense oligonucleotides for the prevention of retinal cell death in the glaucomatous eye
JP4754819B2 (ja) * 2002-05-07 2011-08-24 セネスコ テクノロジーズ，インコーポレイティド アポトーシス調節に関する核酸、ポリペプチド及び方法
NZ542665A (en) 2003-03-05 2008-05-30 Senesco Technologies Inc Use of antisense oligonucleotides or siRNA to suppress expression of eIF-5A1
KR20060013428A (ko) * 2003-06-06 2006-02-09 세네스코 테크놀로지스 인코포레이티드 항-염증 치료제로서 안티센스 올리고뉴클레오타이드 및에스아이알엔에이로의 아폽토시스-특이적이아이에프-5에이(＂이아이에프-5에이1＂)의 저해
CA2717637A1 (en) 2008-03-07 2009-09-17 Senesco Technologies, Inc. Use of sirna to achieve down regulation of an endogenous gene in combination with the use of a sense construct to achieve expression of a desired polynucleotide
US8445638B2 (en) 2008-09-03 2013-05-21 Senesco Technologies, Inc. Use of a truncated eIF-5A1 polynucleotide to induce apoptosis in cancer cells

Also Published As

Publication number Publication date
EP0811060A1 (en) 1997-12-10
WO1996025492A1 (en) 1996-08-22
HUP9801681A3 (en) 2000-10-30
IL117113A0 (en) 1996-06-18
KR19980702160A (ko) 1998-07-15
JPH10509327A (ja) 1998-09-14
FI972763A7 (fi) 1997-10-10
FI972763A0 (fi) 1997-06-26
HUP9801681A2 (hu) 1998-10-28
MX9705757A (es) 1998-07-31
NO973679L (no) 1997-10-13
SK109997A3 (en) 1998-04-08
AU4665196A (en) 1996-09-04
CZ255397A3 (cs) 1998-02-18
CA2210538A1 (en) 1996-08-22
CN1173897A (zh) 1998-02-18
BR9606951A (pt) 1997-10-28
NO973679D0 (no) 1997-08-11
PL321239A1 (en) 1997-11-24

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