FI972708L - Immunoterapeutiska imider/amider och användning därav för reducering av nivåerna för TNFalfa - Google Patents
Immunoterapeutiska imider/amider och användning därav för reducering av nivåerna för TNFalfa Download PDFInfo
- Publication number
- FI972708L FI972708L FI972708A FI972708A FI972708L FI 972708 L FI972708 L FI 972708L FI 972708 A FI972708 A FI 972708A FI 972708 A FI972708 A FI 972708A FI 972708 L FI972708 L FI 972708L
- Authority
- FI
- Finland
- Prior art keywords
- amides
- immunotherapeutic
- imides
- tnfalpha levels
- tnfalpha
- Prior art date
Links
- 108060008682 Tumor Necrosis Factor Proteins 0.000 title 1
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 title 1
- 150000001408 amides Chemical class 0.000 title 1
- 150000003949 imides Chemical class 0.000 title 1
- 230000001024 immunotherapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36666794A | 1994-12-30 | 1994-12-30 | |
| PCT/US1995/015119 WO1996020705A1 (en) | 1994-12-30 | 1995-11-20 | IMMUNOTHERAPEUTIC IMIDES/AMIDES AND THEIR USE FOR REDUCING LEVELS OF TNF$g(a) |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI972708A0 FI972708A0 (sv) | 1997-06-23 |
| FI972708A7 FI972708A7 (sv) | 1997-08-29 |
| FI972708L true FI972708L (sv) | 1997-08-29 |
Family
ID=23443993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI972708A FI972708L (sv) | 1994-12-30 | 1995-11-20 | Immunoterapeutiska imider/amider och användning därav för reducering av nivåerna för TNFalfa |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0797437B1 (sv) |
| JP (1) | JPH10511678A (sv) |
| AT (1) | ATE200621T1 (sv) |
| AU (1) | AU696817B2 (sv) |
| CA (1) | CA2208672C (sv) |
| CZ (1) | CZ290372B6 (sv) |
| DE (1) | DE69520750T2 (sv) |
| DK (1) | DK0797437T3 (sv) |
| ES (1) | ES2155537T3 (sv) |
| FI (1) | FI972708L (sv) |
| GR (1) | GR3036131T3 (sv) |
| HU (1) | HU226558B1 (sv) |
| NZ (1) | NZ296925A (sv) |
| PL (1) | PL185101B1 (sv) |
| PT (1) | PT797437E (sv) |
| RU (1) | RU2164514C2 (sv) |
| SK (1) | SK86997A3 (sv) |
| WO (1) | WO1996020705A1 (sv) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5658940A (en) * | 1995-10-06 | 1997-08-19 | Celgene Corporation | Succinimide and maleimide cytokine inhibitors |
| EP0818439B1 (en) * | 1996-07-02 | 1999-10-13 | Nisshin Flour Milling Co., Ltd. | Imide derivatives |
| EP1661566A3 (en) * | 1996-08-05 | 2008-04-16 | Myriad Genetics, Inc. | Use of beta-sheet mimetics as protease and kinase inhibitors and as inhibitors of transcription factors |
| ES2262184T3 (es) * | 1996-08-05 | 2006-11-16 | Myriad Genetics, Inc. | Utilizacion de mimeticos de hojas beta como inhibidores de proteasa y de kinasa o como inhibidores de factores de transcripcion. |
| US7091353B2 (en) | 2000-12-27 | 2006-08-15 | Celgene Corporation | Isoindole-imide compounds, compositions, and uses thereof |
| JP2004525109A (ja) | 2001-02-15 | 2004-08-19 | キング・ファーマシューティカルズ・インコーポレイティッド | 安定化された甲状腺ホルモン医薬組成物、及びその製法 |
| EP1389203B8 (en) | 2001-02-27 | 2010-03-10 | The Governement of the United States of America, represented by The Secretary Department of Health and Human services | Analogs of thalidomide as angiogenesis inhibitors |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
| US7498171B2 (en) | 2002-04-12 | 2009-03-03 | Anthrogenesis Corporation | Modulation of stem and progenitor cell differentiation, assays, and uses thereof |
| US8952895B2 (en) | 2011-06-03 | 2015-02-10 | Apple Inc. | Motion-based device operations |
| WO2005028436A2 (en) | 2003-09-17 | 2005-03-31 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Thalidomide analogs as tnf-alpha modulators |
| US8927725B2 (en) | 2011-12-02 | 2015-01-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Thio compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4467097A (en) * | 1982-09-29 | 1984-08-21 | General Electric Company | Method for making aromatic bis(etherimide)s |
| AU1531492A (en) * | 1991-02-14 | 1992-09-15 | Rockefeller University, The | Method for controlling abnormal concentration tnf alpha in human tissues |
| US5463063A (en) * | 1993-07-02 | 1995-10-31 | Celgene Corporation | Ring closure of N-phthaloylglutamines |
-
1995
- 1995-11-20 JP JP8520977A patent/JPH10511678A/ja active Pending
- 1995-11-20 WO PCT/US1995/015119 patent/WO1996020705A1/en not_active Ceased
- 1995-11-20 NZ NZ296925A patent/NZ296925A/en unknown
- 1995-11-20 EP EP95940063A patent/EP0797437B1/en not_active Expired - Lifetime
- 1995-11-20 ES ES95940063T patent/ES2155537T3/es not_active Expired - Lifetime
- 1995-11-20 AT AT95940063T patent/ATE200621T1/de not_active IP Right Cessation
- 1995-11-20 PL PL95321071A patent/PL185101B1/pl not_active IP Right Cessation
- 1995-11-20 AU AU41667/96A patent/AU696817B2/en not_active Ceased
- 1995-11-20 DE DE69520750T patent/DE69520750T2/de not_active Expired - Fee Related
- 1995-11-20 PT PT95940063T patent/PT797437E/pt unknown
- 1995-11-20 DK DK95940063T patent/DK0797437T3/da active
- 1995-11-20 RU RU97112903/04A patent/RU2164514C2/ru not_active IP Right Cessation
- 1995-11-20 HU HU9701842A patent/HU226558B1/hu not_active IP Right Cessation
- 1995-11-20 FI FI972708A patent/FI972708L/sv unknown
- 1995-11-20 CZ CZ19972035A patent/CZ290372B6/cs not_active IP Right Cessation
- 1995-11-20 CA CA002208672A patent/CA2208672C/en not_active Expired - Fee Related
- 1995-11-20 SK SK869-97A patent/SK86997A3/sk unknown
-
2001
- 2001-06-27 GR GR20010400984T patent/GR3036131T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CZ203597A3 (en) | 1997-11-12 |
| ATE200621T1 (de) | 2001-05-15 |
| DK0797437T3 (da) | 2001-06-05 |
| DE69520750T2 (de) | 2001-09-13 |
| PL321071A1 (en) | 1997-11-24 |
| PL185101B1 (pl) | 2003-02-28 |
| CA2208672A1 (en) | 1996-07-11 |
| FI972708A7 (sv) | 1997-08-29 |
| DE69520750D1 (de) | 2001-05-23 |
| GR3036131T3 (en) | 2001-09-28 |
| CZ290372B6 (cs) | 2002-07-17 |
| RU2164514C2 (ru) | 2001-03-27 |
| WO1996020705A1 (en) | 1996-07-11 |
| AU4166796A (en) | 1996-07-24 |
| JPH10511678A (ja) | 1998-11-10 |
| ES2155537T3 (es) | 2001-05-16 |
| AU696817B2 (en) | 1998-09-17 |
| EP0797437B1 (en) | 2001-04-18 |
| CA2208672C (en) | 2008-02-12 |
| EP0797437A1 (en) | 1997-10-01 |
| FI972708A0 (sv) | 1997-06-23 |
| NZ296925A (en) | 1998-06-26 |
| PT797437E (pt) | 2001-07-31 |
| SK86997A3 (en) | 1998-01-14 |
| HUT77978A (hu) | 1999-01-28 |
| HU226558B1 (en) | 2009-03-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI990180A7 (sv) | Nya immunoterapeutiska medel och deras användning för nedsättning av cytokin-nivåer | |
| IS4481A (is) | Díhýdrópyramídín og notkun þeirra | |
| DE69412130D1 (de) | Kühlcontainer und endrahmen | |
| FI951801A7 (sv) | CTLA4-molekyler och IL4-bindande molekyler samt anvädning av dessa | |
| KR960012626A (ko) | 클립 및 그 제작 방법 | |
| NO2008002I2 (no) | Protiokonazol og salter derav | |
| BR9506832A (pt) | N-pirazolilanilinas e n-pirazolilaminopiridinas | |
| DE69513307D1 (de) | Zusammensetzung und verwendung | |
| BR9502407A (pt) | Composição lubrificante e concetrado | |
| FI972245A0 (sv) | Mesomonojodsubstituerade tetramakrocykliska föreningar samt förfarande för framställning och användning därav | |
| FI972708A7 (sv) | Immunoterapeutiska imider/amider och användning därav för reducering a v nivåerna för TNFalfa | |
| PT755386E (pt) | Derivado de benzamida composicoes contendo o referido derivado e sua utilizacao | |
| FI965043A7 (sv) | Melatoninreceptorer med hög affinitet och användning av dessa | |
| BR9510062A (pt) | Macromonômeto esterificado e composição | |
| NO964541D0 (no) | Porphacyanin og CNC-utvidete porphyriner | |
| FI955261A7 (sv) | Antikroppar mot P-sekektin och deras användning | |
| DE69600829D1 (de) | Mikrobizide Zusammensetzung und deren Verwendung | |
| IT1273540B (it) | Fosfiti-hals e fosforammidi-hals come stabilizzanti | |
| DE69530446D1 (de) | Ozonisator und seine Verwendung | |
| NO972216D0 (no) | Acrotein-frigjörende sammensetning og dens anvendelse | |
| DE69506459D1 (de) | Zwirnverfahren und Zwirnvorrichtung | |
| FI964854A7 (sv) | Framställning av hydroxitioacetamider och deras användning i syntes av bensotiofener | |
| BR9507133A (pt) | N-aril e n-alquilsulfonilaminais | |
| NO954530D0 (no) | Aryloksycykloalkenyl- og aryloksyimino-cykloalkenylhydroksyurinstoffer | |
| KR960006792U (ko) | 건명태 타연기 |