FI970447L - Pregnaaneja ja kolaaneja hypotalamuksen toiminnan muutoksen neurokemiallisina initiaattoreina - Google Patents

Pregnaaneja ja kolaaneja hypotalamuksen toiminnan muutoksen neurokemiallisina initiaattoreina Download PDF

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Publication number
FI970447L
FI970447L FI970447A FI970447A FI970447L FI 970447 L FI970447 L FI 970447L FI 970447 A FI970447 A FI 970447A FI 970447 A FI970447 A FI 970447A FI 970447 L FI970447 L FI 970447L
Authority
FI
Finland
Prior art keywords
cholanes
pregnanes
function changes
hypothalamic function
neurochemical initiators
Prior art date
Application number
FI970447A
Other languages
English (en)
Swedish (sv)
Other versions
FI970447A7 (fi
FI970447A0 (fi
Inventor
Clive L Jennings-White
David L Berliner
Nathan William Adams
Original Assignee
Pherin Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/286,073 external-priority patent/US5563131A/en
Application filed by Pherin Corp filed Critical Pherin Corp
Publication of FI970447A0 publication Critical patent/FI970447A0/fi
Publication of FI970447A7 publication Critical patent/FI970447A7/fi
Publication of FI970447L publication Critical patent/FI970447L/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI970447A 1994-08-04 1995-08-04 Pregnaaneja ja kolaaneja hypotalamuksen toiminnan muutoksen neurokemiallisina initiaattoreina FI970447L (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/286,073 US5563131A (en) 1994-08-04 1994-08-04 Pregnane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
US08/510,957 US5994333A (en) 1994-08-04 1995-08-03 Pregnane and cholane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
PCT/US1995/009634 WO1996004296A1 (en) 1994-08-04 1995-08-04 Pregnanes and cholanes as neurochemical initiators of change in hypothalamic function

Publications (3)

Publication Number Publication Date
FI970447A0 FI970447A0 (fi) 1997-02-03
FI970447A7 FI970447A7 (fi) 1997-04-03
FI970447L true FI970447L (fi) 1997-04-03

Family

ID=26963568

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970447A FI970447L (fi) 1994-08-04 1995-08-04 Pregnaaneja ja kolaaneja hypotalamuksen toiminnan muutoksen neurokemiallisina initiaattoreina

Country Status (11)

Country Link
US (1) US5994333A (fi)
EP (1) EP0775154A4 (fi)
CN (1) CN1173181A (fi)
BR (1) BR9508519A (fi)
CA (1) CA2196690C (fi)
CZ (1) CZ32997A3 (fi)
FI (1) FI970447L (fi)
MX (1) MX9700881A (fi)
NO (1) NO311328B1 (fi)
NZ (1) NZ291056A (fi)
PL (1) PL318521A1 (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030045514A1 (en) * 2001-05-03 2003-03-06 Louis Monti 17-Methyleneandrostan-3alpha-ol analogs as CRH inhibitors
WO2009039103A2 (en) * 2007-09-17 2009-03-26 Human Pheromone Sciences, Inc. Fragrance compositions and other compositions which contain naturally occurring substances found in corals
EP2278880B1 (en) 2008-04-09 2012-10-10 Pherin Pharmaceuticals, Inc. Steroid treatment for hot flashes
EP2938346B1 (en) * 2012-12-28 2017-04-05 Pherin Pharmaceuticals, Inc. Use of pregn-4-en-20-yn-3-one for the treatment of depressive disorders
CN114128658B (zh) * 2021-11-25 2023-03-24 中国水产科学研究院黑龙江水产研究所 一种用于人工鱼巢的改性椰丝材料的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
DE69435286D1 (de) * 1993-05-24 2010-05-20 Purdue Pharma Ltd Verfahren und zusammensetzungen zum hervorrufen von schlaf
ES2210242T3 (es) * 1993-06-15 2004-07-01 Pherin Pharmaceuticals, Inc. Esteroides de estreno como iniciadores neuroquimicos del cambio en la funcion hipotalamica humana y composiciones farmaceuticas relacionadas.
HUT74172A (en) * 1993-06-15 1996-11-28 Pherin Corp Androstane steroids as neurochemical initilators of change in human hypothalamic function and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
NZ291056A (en) 2001-03-30
FI970447A7 (fi) 1997-04-03
FI970447A0 (fi) 1997-02-03
CZ32997A3 (en) 1997-09-17
NO970472L (no) 1997-04-03
PL318521A1 (en) 1997-06-23
EP0775154A4 (en) 2001-05-09
US5994333A (en) 1999-11-30
BR9508519A (pt) 1998-07-14
CA2196690C (en) 2008-01-08
NO311328B1 (no) 2001-11-19
CN1173181A (zh) 1998-02-11
EP0775154A1 (en) 1997-05-28
NO970472D0 (no) 1997-02-03
CA2196690A1 (en) 1996-02-15
MX9700881A (es) 1997-04-30

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