FI963570A - 8-substituoidut tetrahydro-beeta-karboliinit - Google Patents

8-substituoidut tetrahydro-beeta-karboliinit Download PDF

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Publication number
FI963570A
FI963570A FI963570A FI963570A FI963570A FI 963570 A FI963570 A FI 963570A FI 963570 A FI963570 A FI 963570A FI 963570 A FI963570 A FI 963570A FI 963570 A FI963570 A FI 963570A
Authority
FI
Finland
Prior art keywords
carbolines
beta
substituted tetrahydro
tetrahydro
substituted
Prior art date
Application number
FI963570A
Other languages
English (en)
Swedish (sv)
Other versions
FI963570A0 (fi
Inventor
James Edmund Audia
James Joseph Droste
Jeffrey Scott Nissen
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI963570A0 publication Critical patent/FI963570A0/fi
Publication of FI963570A publication Critical patent/FI963570A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI963570A 1994-03-11 1996-09-10 8-substituoidut tetrahydro-beeta-karboliinit FI963570A (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21240494A 1994-03-11 1994-03-11
US08/380,564 US5631265A (en) 1994-03-11 1995-02-06 8-substituted tetrahydro-beta-carbolines
PCT/US1995/003085 WO1995024191A1 (en) 1994-03-11 1995-03-10 8-substituted tetrahydro-beta-carbolines

Publications (2)

Publication Number Publication Date
FI963570A0 FI963570A0 (fi) 1996-09-10
FI963570A true FI963570A (fi) 1996-09-10

Family

ID=26907107

Family Applications (1)

Application Number Title Priority Date Filing Date
FI963570A FI963570A (fi) 1994-03-11 1996-09-10 8-substituoidut tetrahydro-beeta-karboliinit

Country Status (8)

Country Link
US (1) US5631265A (fi)
EP (1) EP0751770A4 (fi)
JP (1) JPH09510215A (fi)
AU (1) AU1996295A (fi)
CA (1) CA2185235A1 (fi)
FI (1) FI963570A (fi)
IL (1) IL112959A0 (fi)
WO (1) WO1995024191A1 (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869497A (en) * 1996-03-15 1999-02-09 Eli Lilly And Company Method of treating or ameliorating the symptoms of common cold or allergic rhinitis
AU3485999A (en) 1998-04-10 1999-11-01 Mayo Foundation For Medical Education And Research Neo-tryptophan
FR2824829B1 (fr) * 2001-05-16 2005-06-03 Macef Nouveaux derives de dihydroimidazo [5,1-a]-beta-carboline, leur procede de preparation et leur application a titre de medicament
US7087575B2 (en) * 2002-07-18 2006-08-08 Mayo Foundation For Medical Education And Research Treating the effect of nicotine
DE10252667A1 (de) * 2002-11-11 2004-05-27 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
GB2422828A (en) * 2005-02-03 2006-08-09 Hunter Fleming Ltd Tricyclic cytoprotective compounds comprising an indole residue
DE102005016460A1 (de) * 2005-04-11 2006-10-19 Grünenthal GmbH Spriocyclische Cyclohexanderivate zur Behandlung von Substanzabhängigkeit
RU2338537C2 (ru) * 2006-01-25 2008-11-20 Сергей Олегович Бачурин СРЕДСТВО ДЛЯ ЛЕЧЕНИЯ ШИЗОФРЕНИИ НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b)ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ
WO2007100718A2 (en) * 2006-02-24 2007-09-07 Denise Barbut Neurotensin receptor agonists and opioid receptor agonists
DE102007009235A1 (de) 2007-02-22 2008-09-18 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
EP2175724A4 (en) * 2007-08-01 2010-09-15 Medivation Neurology Inc METHOD AND COMPOSITIONS FOR TREATING SCHIZOPHRENIA USING ANTIPSYCHOTIC COMBINATION THERAPY
BRPI0906244A2 (pt) * 2008-03-24 2015-06-30 Medivation Technologies Inc Composto, composição farmacêutica, método para tratar um distúrbio cognitivo, psicótico, mediado por neurotransmissores ou um distúrbio neuronal em um indivíduo, uso de um composto e kit
RU2515895C2 (ru) * 2008-03-27 2014-05-20 Грюненталь Гмбх Производные спиро(5.5)ундекана
PE20091650A1 (es) * 2008-03-27 2009-11-07 Gruenenthal Chemie Derivados de ciclohexano espirociclicos sustituidos
PT2271613E (pt) * 2008-03-27 2014-07-16 Gruenenthal Gmbh Hidroximetilciclo-hexilamina
US20090247530A1 (en) 2008-03-27 2009-10-01 Grunenthal Gmbh Substituted 4-aminocyclohexane derivatives
JP5529843B2 (ja) * 2008-03-27 2014-06-25 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 置換シクロヘキシルジアミン
MX2010010619A (es) * 2008-03-28 2010-12-17 Altiris Therapeutics Moduladores de quimioquina.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3071589A (en) * 1959-06-10 1963-01-01 Sterling Drug Inc 3-benzyl-4-lower-alkyl-3, 4, 5, 6-tetrahydro-4-carboline quaternary ammonium salts and preparation thereof
US3304309A (en) * 1963-08-19 1967-02-14 Warner Lambert Pharmaceutical 1-substituted-6-acetyl-1, 2, 3, 4-tetrahydro-beta-carbolines and process for their production
US3455943A (en) * 1966-10-21 1969-07-15 American Cyanamid Co Certain 5,8-dihydro-beta-carbolines
US3492304A (en) * 1968-06-24 1970-01-27 Warner Lambert Pharmaceutical 5,6,7,7a,8,8a,9,10,12,12a-decahydro-11h-benz(b)indolo(3,2,1-ij) 1,5 naphthyridin-11-ones
US3718657A (en) * 1970-12-03 1973-02-27 Abbott Lab Certain-2-substituted-1,2,3,4-tetrahydro-beta or gamma carbolines
DK72180A (da) * 1979-04-10 1980-10-11 Ciba Geigy Ag Fremgangsmaade til fremstilling af diazatricycler samt salte deraf
US4978669A (en) * 1989-06-08 1990-12-18 Neurex Corporation Method of suppressing appetite by administration of tetrahydro-beta-carboline derivatives

Also Published As

Publication number Publication date
FI963570A0 (fi) 1996-09-10
CA2185235A1 (en) 1995-09-14
WO1995024191A1 (en) 1995-09-14
US5631265A (en) 1997-05-20
EP0751770A1 (en) 1997-01-08
EP0751770A4 (en) 1997-06-11
IL112959A0 (en) 1995-06-29
JPH09510215A (ja) 1997-10-14
AU1996295A (en) 1995-09-25

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