FI963103A0 - Ei-virusvektori - Google Patents
Ei-virusvektoriInfo
- Publication number
- FI963103A0 FI963103A0 FI963103A FI963103A FI963103A0 FI 963103 A0 FI963103 A0 FI 963103A0 FI 963103 A FI963103 A FI 963103A FI 963103 A FI963103 A FI 963103A FI 963103 A0 FI963103 A0 FI 963103A0
- Authority
- FI
- Finland
- Prior art keywords
- viral vector
- cell
- biotin
- administration
- human
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6891—Pre-targeting systems involving an antibody for targeting specific cells
- A61K47/6897—Pre-targeting systems with two or three steps using antibody conjugates; Ligand-antiligand therapies
- A61K47/6898—Pre-targeting systems with two or three steps using antibody conjugates; Ligand-antiligand therapies using avidin- or biotin-conjugated antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nanotechnology (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medical Informatics (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19265594A | 1994-02-07 | 1994-02-07 | |
PCT/US1995/001161 WO1995021195A1 (en) | 1994-02-07 | 1995-02-06 | Non-viral vector |
Publications (2)
Publication Number | Publication Date |
---|---|
FI963103A0 true FI963103A0 (fi) | 1996-08-06 |
FI963103A FI963103A (fi) | 1996-10-01 |
Family
ID=22710534
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI963103A FI963103A (fi) | 1994-02-07 | 1996-08-06 | Ei-virusvektori |
Country Status (16)
Country | Link |
---|---|
US (1) | US6214974B1 (fi) |
EP (1) | EP0743958B1 (fi) |
JP (1) | JP4015693B2 (fi) |
KR (1) | KR100376390B1 (fi) |
CN (1) | CN1200950C (fi) |
AT (1) | ATE245662T1 (fi) |
AU (1) | AU695564B2 (fi) |
CA (1) | CA2182616A1 (fi) |
DE (1) | DE69531342D1 (fi) |
FI (1) | FI963103A (fi) |
IL (1) | IL112372A (fi) |
NO (1) | NO319899B1 (fi) |
NZ (1) | NZ281763A (fi) |
RU (1) | RU2164943C2 (fi) |
SA (1) | SA95150519B1 (fi) |
WO (1) | WO1995021195A1 (fi) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ237688A (en) * | 1990-04-19 | 1993-01-27 | Res Dev Foundation | Antibody-cytotoxic immunoconjugate-containing compositions and cancer treatment |
WO1995022086A1 (en) * | 1994-02-08 | 1995-08-17 | Nippon Steel Corporation | Liquid development type multi-color image formation apparatus |
DE19605279A1 (de) * | 1996-02-13 | 1997-08-14 | Hoechst Ag | Zielzellspezifische Vektoren für die Einschleusung von Genen in Zellen, Arzneimittel enthaltend derartige Vektoren und deren Verwendung |
EP1098666B1 (en) * | 1998-07-17 | 2013-01-16 | The United States of America, represented by the Secretary, Department of Health and Human Services | Water-soluble drugs and methods for their production |
FR2793414B1 (fr) * | 1999-05-10 | 2003-05-23 | Centre Nat Rech Scient | Conjugue acide nucleique-anticorps pour delivrer un acide nucleique etranger dans les cellules |
GB9930533D0 (en) * | 1999-12-23 | 2000-02-16 | Mitsubishi Tokyo Pharm Inc | Nucleic acid delivery |
ZA200305980B (en) | 2001-02-12 | 2007-01-31 | Res Dev Foundation | Modified proteins, designer toxins, and methods of making thereof |
US7265208B2 (en) * | 2001-05-01 | 2007-09-04 | The Regents Of The University Of California | Fusion molecules and treatment of IgE-mediated allergic diseases |
EP1404707A4 (en) * | 2001-05-29 | 2005-02-02 | Univ Michigan | SYSTEMS AND METHODS FOR PROTEIN ANALYSIS |
WO2002102972A2 (en) * | 2001-06-20 | 2002-12-27 | Prochon Biotech Ltd. | Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof |
ATE477280T1 (de) * | 2001-06-28 | 2010-08-15 | Domantis Ltd | Doppelspezifischer ligand und dessen verwendung |
US20050271663A1 (en) * | 2001-06-28 | 2005-12-08 | Domantis Limited | Compositions and methods for treating inflammatory disorders |
CN1555268B (zh) * | 2001-07-17 | 2013-04-03 | 研究发展基金会 | 含促调亡蛋白质的治疗剂 |
AU2002323845A1 (en) * | 2002-04-02 | 2003-10-13 | "Asgl-Farmatsevticheskie Innovatsii", Zakrytoe Aktsionernoe Obschestvo | Recombinant chimeric protein for the target delivery of dna to eukariotic target cells |
CA2488858A1 (en) * | 2002-06-12 | 2003-12-24 | Research Development Foundation | Immunotoxin as a therapeutic agent and uses thereof |
US9321832B2 (en) * | 2002-06-28 | 2016-04-26 | Domantis Limited | Ligand |
US7696320B2 (en) | 2004-08-24 | 2010-04-13 | Domantis Limited | Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor |
JP2006512895A (ja) * | 2002-06-28 | 2006-04-20 | ドマンティス リミテッド | リガンド |
EP1578801A2 (en) * | 2002-12-27 | 2005-09-28 | Domantis Limited | Dual specific single domain antibodies specific for a ligand and for the receptor of the ligand |
WO2005074417A2 (en) * | 2003-09-03 | 2005-08-18 | Salk Institute For Biological Studies | Multiple antigen detection assays and reagents |
CN101104856B (zh) * | 2003-11-18 | 2010-11-10 | 中国医学科学院基础医学研究所 | 一个系列的非病毒载体及包含其的药物组合物 |
US20060171919A1 (en) * | 2005-02-01 | 2006-08-03 | Research Development Foundation | Targeted polypeptides |
CA2632866A1 (en) * | 2005-12-01 | 2007-06-07 | Domantis Limited | Noncompetitive domain antibody formats that bind interleukin 1 receptor type 1 |
EA200901301A1 (ru) * | 2007-06-06 | 2010-06-30 | Домантис Лимитед | Полипептиды, вариабельные домены антител и антагонисты |
TWI689314B (zh) | 2010-11-30 | 2020-04-01 | 建南德克公司 | 低親和力血腦障壁受體抗體及其用途 |
US9623117B2 (en) * | 2011-04-04 | 2017-04-18 | Wisconsin Alumni Research Foundation | Method for selective targeting and entry of bacterial toxins to cells |
KR20140146993A (ko) | 2011-05-11 | 2014-12-29 | 칠드런'즈 메디컬 센터 코포레이션 | 다항원 제시 면역성 조성물, 및 그 방법 및 용도 |
US11576958B2 (en) | 2013-02-07 | 2023-02-14 | Children's Medical Center Corporation | Protein antigens that provide protection against pneumococcal colonization and/or disease |
UY36519A (es) * | 2015-01-16 | 2016-08-31 | Hope City | Anticuerpos de penetración celular |
AU2018243910A1 (en) | 2017-03-28 | 2019-11-14 | The Children's Medical Center Corporation | A multiple antigen presenting system (MAPS)-based staphylococcus aureus vaccine, immunogenic composition, and uses thereof |
CN111065417B (zh) | 2017-06-23 | 2024-04-19 | 美商艾芬尼维克斯公司 | 免疫原性组合物 |
JP2021535921A (ja) | 2018-09-12 | 2021-12-23 | アフィニバックス、インコーポレイテッド | 多価肺炎球菌ワクチン |
CN116848146A (zh) | 2020-09-03 | 2023-10-03 | I·S·Y·陈 | 可溶性碱性磷酸酶构建体和包含编码可溶性碱性磷酸酶构建体的多核苷酸的表达载体 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4545985A (en) * | 1984-01-26 | 1985-10-08 | The United States Of America As Represented By The Secretary, Dept. Of Health And Human Services | Pseudomonas exotoxin conjugate immunotoxins |
US5525338A (en) * | 1992-08-21 | 1996-06-11 | Immunomedics, Inc. | Detection and therapy of lesions with biotin/avidin conjugates |
US4863713A (en) * | 1986-06-23 | 1989-09-05 | The Board Of Trustees Of Leland Stanford Jr. Univ. | Method and system for administering therapeutic and diagnostic agents |
US5026785A (en) * | 1989-05-12 | 1991-06-25 | The United States Of America As Represented By The Department Of Health And Human Services | Avidin and streptavidin modified water-soluble polymers such as polyacrylamide, and the use thereof in the construction of soluble multivalent macromolecular conjugates |
IT1245748B (it) * | 1990-12-21 | 1994-10-14 | Mini Ricerca Scient Tecnolog | Preparazione includente anticorpi monoclonali biotinilati, avidina e biotina, per la diagnosi di affezioni tumorali e suo impiego |
ZA932523B (en) * | 1992-04-10 | 1994-10-08 | Res Dev Foundation | Immunotoxins directed against cd33 related surface antigens |
ZA932522B (en) * | 1992-04-10 | 1993-12-20 | Res Dev Foundation | Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens |
JPH07507804A (ja) * | 1992-06-09 | 1995-08-31 | ネオルックス コーポレーション | 予備標的化方法及び化合物 |
US5482698A (en) * | 1993-04-22 | 1996-01-09 | Immunomedics, Inc. | Detection and therapy of lesions with biotin/avidin polymer conjugates |
AU683893B2 (en) * | 1993-05-17 | 1997-11-27 | Immunomedics Inc. | Improved detection and therapy of lesions with biotin/avidin-metal chelating protein conjugates |
WO1995015979A1 (en) * | 1993-12-07 | 1995-06-15 | Neorx Corporation | Pretargeting methods and compounds |
-
1995
- 1995-01-18 IL IL11237295A patent/IL112372A/xx not_active IP Right Cessation
- 1995-02-06 RU RU96118117/13A patent/RU2164943C2/ru not_active IP Right Cessation
- 1995-02-06 EP EP95910893A patent/EP0743958B1/en not_active Expired - Lifetime
- 1995-02-06 WO PCT/US1995/001161 patent/WO1995021195A1/en active IP Right Grant
- 1995-02-06 AT AT95910893T patent/ATE245662T1/de not_active IP Right Cessation
- 1995-02-06 NZ NZ281763A patent/NZ281763A/en not_active IP Right Cessation
- 1995-02-06 JP JP52066595A patent/JP4015693B2/ja not_active Expired - Fee Related
- 1995-02-06 CN CNB951920138A patent/CN1200950C/zh not_active Expired - Fee Related
- 1995-02-06 KR KR1019960704269A patent/KR100376390B1/ko not_active IP Right Cessation
- 1995-02-06 AU AU18687/95A patent/AU695564B2/en not_active Ceased
- 1995-02-06 DE DE69531342T patent/DE69531342D1/de not_active Expired - Lifetime
- 1995-02-06 CA CA002182616A patent/CA2182616A1/en not_active Abandoned
- 1995-03-12 SA SA95150519A patent/SA95150519B1/ar unknown
- 1995-03-27 US US08/410,390 patent/US6214974B1/en not_active Expired - Fee Related
-
1996
- 1996-08-06 FI FI963103A patent/FI963103A/fi not_active Application Discontinuation
- 1996-08-06 NO NO19963283A patent/NO319899B1/no unknown
Also Published As
Publication number | Publication date |
---|---|
JPH09508792A (ja) | 1997-09-09 |
WO1995021195A1 (en) | 1995-08-10 |
NO319899B1 (no) | 2005-09-26 |
NO963283L (no) | 1996-08-06 |
NZ281763A (en) | 2001-06-29 |
AU695564B2 (en) | 1998-08-13 |
EP0743958B1 (en) | 2003-07-23 |
FI963103A (fi) | 1996-10-01 |
CN1200950C (zh) | 2005-05-11 |
ATE245662T1 (de) | 2003-08-15 |
RU2164943C2 (ru) | 2001-04-10 |
KR100376390B1 (ko) | 2003-06-12 |
AU1868795A (en) | 1995-08-21 |
JP4015693B2 (ja) | 2007-11-28 |
EP0743958A4 (en) | 1999-07-28 |
SA95150519B1 (ar) | 2005-07-24 |
EP0743958A1 (en) | 1996-11-27 |
IL112372A0 (en) | 1995-03-30 |
US6214974B1 (en) | 2001-04-10 |
NO963283D0 (no) | 1996-08-06 |
IL112372A (en) | 2001-08-26 |
DE69531342D1 (de) | 2003-08-28 |
KR970700771A (ko) | 1997-02-12 |
CN1143374A (zh) | 1997-02-19 |
CA2182616A1 (en) | 1995-08-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed |