FI962592A - New intermediates for synthesizing L-aspartyl-D-alpha-aminoalkanoyl (S) -N-alpha-alkylbenzylamides useful as artificial sweeteners - Google Patents

New intermediates for synthesizing L-aspartyl-D-alpha-aminoalkanoyl (S) -N-alpha-alkylbenzylamides useful as artificial sweeteners Download PDF

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Publication number
FI962592A
FI962592A FI962592A FI962592A FI962592A FI 962592 A FI962592 A FI 962592A FI 962592 A FI962592 A FI 962592A FI 962592 A FI962592 A FI 962592A FI 962592 A FI962592 A FI 962592A
Authority
FI
Finland
Prior art keywords
alpha
alkylbenzylamides
aminoalkanoyl
aspartyl
synthesizing
Prior art date
Application number
FI962592A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI962592A0 (en
Inventor
Angelo Lihong D
James G Sweeny
Iii George A King
Original Assignee
Coca Cola Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coca Cola Co filed Critical Coca Cola Co
Publication of FI962592A publication Critical patent/FI962592A/en
Publication of FI962592A0 publication Critical patent/FI962592A0/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • C07K5/06113Asp- or Asn-amino acid

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI962592A 1993-12-22 1996-06-20 New intermediates for the synthesis of L-aspartyl-D-alpha-aminoalkanoyl- (S) -N-alpha-alkylbenzylamides useful as artificial sweeteners FI962592A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17199693A 1993-12-22 1993-12-22
PCT/US1994/014770 WO1995017418A2 (en) 1993-12-22 1994-12-22 NOVEL INTERMEDIATES FOR THE SYNTHESIS OF L-ASPARTYL-D-α-AMINOALKANOYL-(S)-N-α-ALKYLBENZYL AMIDES USEFUL AS ARTIFICIAL SWEETENERS

Publications (2)

Publication Number Publication Date
FI962592A true FI962592A (en) 1996-06-20
FI962592A0 FI962592A0 (en) 1996-06-20

Family

ID=22625935

Family Applications (1)

Application Number Title Priority Date Filing Date
FI962592A FI962592A0 (en) 1993-12-22 1996-06-20 New intermediates for the synthesis of L-aspartyl-D-alpha-aminoalkanoyl- (S) -N-alpha-alkylbenzylamides useful as artificial sweeteners

Country Status (12)

Country Link
EP (1) EP0736037A1 (en)
JP (1) JPH09507076A (en)
KR (1) KR970700201A (en)
AU (1) AU1442995A (en)
CA (1) CA2179376A1 (en)
FI (1) FI962592A0 (en)
IL (1) IL111990A0 (en)
NO (1) NO962620L (en)
PE (1) PE25195A1 (en)
TW (1) TW282450B (en)
WO (1) WO1995017418A2 (en)
ZA (1) ZA9410199B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5002196A (en) * 1995-03-28 1996-10-16 Novo Nordisk A/S Immunosuppressive agents
US8044173B2 (en) 2005-09-13 2011-10-25 University Of Reading Asymmetric synthesis of peptides
GB0518667D0 (en) * 2005-09-13 2005-10-19 Univ Reading The Method
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411925A (en) * 1980-01-21 1983-10-25 Pfizer Inc. Branched amides of L-aspartyl-d-amino acid dipeptides
US4730076A (en) * 1985-12-18 1988-03-08 Nippon Kayaku Kabushiki Kaisha Process for producing α-aspartyl-phenylalanine ester
AT394854B (en) * 1986-06-12 1992-07-10 Biochemie Gmbh Process for the preparation of N-L-alpha-aspartyl-L- phenylalanine (lower) alkyl esters
DE59009485D1 (en) * 1989-01-26 1995-09-14 Bayer Ag Optically active (meth) acrylic acid derivatives, their preparation, their polymerization into optically active polymers and their use.
US5286509A (en) * 1992-06-22 1994-02-15 The Coca-Cola Company L-aspartyl-D-α-aminoalkanoyl-(S)-N-alpha-alkylbenzyl amides useful as artificial sweeteners

Also Published As

Publication number Publication date
NO962620D0 (en) 1996-06-20
CA2179376A1 (en) 1995-06-29
TW282450B (en) 1996-08-01
ZA9410199B (en) 1995-09-04
FI962592A0 (en) 1996-06-20
EP0736037A1 (en) 1996-10-09
IL111990A0 (en) 1995-03-15
WO1995017418A2 (en) 1995-06-29
NO962620L (en) 1996-08-19
AU1442995A (en) 1995-07-10
KR970700201A (en) 1997-01-08
WO1995017418A3 (en) 1995-10-19
PE25195A1 (en) 1995-09-29
JPH09507076A (en) 1997-07-15

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