FI960465L - 15,15-dialkyylisubstituoituja estradiolin johdannaisia - Google Patents

15,15-dialkyylisubstituoituja estradiolin johdannaisia Download PDF

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Publication number
FI960465L
FI960465L FI960465A FI960465A FI960465L FI 960465 L FI960465 L FI 960465L FI 960465 A FI960465 A FI 960465A FI 960465 A FI960465 A FI 960465A FI 960465 L FI960465 L FI 960465L
Authority
FI
Finland
Prior art keywords
dialkyl
estradiol derivatives
substituted estradiol
substituted
derivatives
Prior art date
Application number
FI960465A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI960465A0 (fi
FI960465A7 (fi
Inventor
James Ronald Bull
Karl-Heinrich Fritzemeier
Christa Hegele-Hartung
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of FI960465A0 publication Critical patent/FI960465A0/fi
Publication of FI960465A7 publication Critical patent/FI960465A7/fi
Publication of FI960465L publication Critical patent/FI960465L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI960465A 1993-08-02 1994-08-01 15,15-dialkyylisubstituoituja estradiolin johdannaisia FI960465L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4326240A DE4326240A1 (de) 1993-08-02 1993-08-02 15,15-Dialkyl-substituierte Derivate des Estradiols
PCT/EP1994/002540 WO1995004070A1 (en) 1993-08-02 1994-08-01 15,15-dialkyl-substituted derivatives of estradiol

Publications (3)

Publication Number Publication Date
FI960465A0 FI960465A0 (fi) 1996-02-01
FI960465A7 FI960465A7 (fi) 1996-02-01
FI960465L true FI960465L (fi) 1996-02-01

Family

ID=6494482

Family Applications (1)

Application Number Title Priority Date Filing Date
FI960465A FI960465L (fi) 1993-08-02 1994-08-01 15,15-dialkyylisubstituoituja estradiolin johdannaisia

Country Status (21)

Country Link
US (2) US5587496A (de)
EP (1) EP0712412B1 (de)
JP (1) JPH09500891A (de)
KR (1) KR960703940A (de)
CN (1) CN1040329C (de)
AT (1) ATE175418T1 (de)
AU (1) AU674609B2 (de)
CA (1) CA2168657A1 (de)
CZ (1) CZ26796A3 (de)
DE (2) DE4326240A1 (de)
FI (1) FI960465L (de)
HU (1) HUT73238A (de)
IL (1) IL110530A (de)
MY (1) MY111121A (de)
NO (1) NO960425L (de)
NZ (1) NZ271091A (de)
PL (1) PL312792A1 (de)
RU (1) RU2147306C1 (de)
SK (1) SK13596A3 (de)
WO (1) WO1995004070A1 (de)
ZA (1) ZA945754B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4326240A1 (de) * 1993-08-02 1995-02-09 Schering Ag 15,15-Dialkyl-substituierte Derivate des Estradiols
DE4447401A1 (de) 1994-12-23 1996-07-04 Schering Ag 14,17-C¶2¶-überbrückte Steroide
DE19906159A1 (de) * 1999-02-09 2000-08-10 Schering Ag 16-Hydroxyestratriene als selektiv wirksame Estrogene
DE10151365A1 (de) * 2001-10-17 2003-04-30 Schering Ag 17-Chlor-D-Homosteroide als selektive Estrogenrezeptorantagonisten
US20050220825A1 (en) * 2004-03-10 2005-10-06 Adrian Funke Molecular dispersions of drospirenone
MY142989A (en) * 2004-03-10 2011-02-14 Bayer Schering Pharma Ag Stabilised supersaturated solids of lipophilic drugs
KR20060130723A (ko) * 2004-03-10 2006-12-19 쉐링 악티엔게젤샤프트 분자 분산된 드로스피레논을 포함하는 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2275752A (en) * 1938-11-25 1942-03-10 Ciba Pharm Prod Inc Cyclic condensation products and process of making same
US3472881A (en) * 1965-05-14 1969-10-14 Merck & Co Inc 3 - hydroxy - 13 - lower alkyl - 15 - carboxyl - 1,3,5(10),8,14 - gonapentaen - 17-ones and intermediates in the production thereof
US3766224A (en) * 1971-06-03 1973-10-16 Sandoz Ag 15-methyl-substituted steroids
DD145919B1 (de) * 1978-06-28 1982-06-30 Kurt Ponsold Verfahren zur herstellung von 14,1 -methylenderivaten der oestranreihe
DE3628189A1 (de) * 1986-08-20 1988-02-25 Schering Ag Oestrogen wirksame mittel und 14,17ss-ethano-14ss-estratriene
DE4326240A1 (de) * 1993-08-02 1995-02-09 Schering Ag 15,15-Dialkyl-substituierte Derivate des Estradiols

Also Published As

Publication number Publication date
MY111121A (en) 1999-08-30
HUT73238A (en) 1996-07-29
AU7461094A (en) 1995-02-28
ZA945754B (en) 1995-03-15
NO960425L (no) 1996-04-02
NZ271091A (en) 1996-08-27
CN1040329C (zh) 1998-10-21
US5587496A (en) 1996-12-24
IL110530A (en) 1998-08-16
KR960703940A (ko) 1996-08-31
CA2168657A1 (en) 1995-02-09
HU9600234D0 (en) 1996-04-29
CZ26796A3 (en) 1996-07-17
PL312792A1 (en) 1996-05-13
US5656622A (en) 1997-08-12
RU2147306C1 (ru) 2000-04-10
SK13596A3 (en) 1997-03-05
DE69415812T2 (de) 1999-09-16
EP0712412A1 (de) 1996-05-22
IL110530A0 (en) 1994-11-11
FI960465A0 (fi) 1996-02-01
EP0712412B1 (de) 1999-01-07
NO960425D0 (no) 1996-02-01
ATE175418T1 (de) 1999-01-15
CN1128031A (zh) 1996-07-31
WO1995004070A1 (en) 1995-02-09
DE4326240A1 (de) 1995-02-09
FI960465A7 (fi) 1996-02-01
AU674609B2 (en) 1997-01-02
JPH09500891A (ja) 1997-01-28
DE69415812D1 (de) 1999-03-18

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Legal Events

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FD Application lapsed