FI954991A - Bicyclic tetrahydropyrazolopyridines - Google Patents

Bicyclic tetrahydropyrazolopyridines Download PDF

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Publication number
FI954991A
FI954991A FI954991A FI954991A FI954991A FI 954991 A FI954991 A FI 954991A FI 954991 A FI954991 A FI 954991A FI 954991 A FI954991 A FI 954991A FI 954991 A FI954991 A FI 954991A
Authority
FI
Finland
Prior art keywords
tetrahydropyrazolopyridines
bicyclic
bicyclic tetrahydropyrazolopyridines
Prior art date
Application number
FI954991A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI954991A0 (en
Inventor
Allen J Duplantier
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI954991A0 publication Critical patent/FI954991A0/en
Publication of FI954991A publication Critical patent/FI954991A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI954991A 1994-10-20 1995-10-19 Bicyclic tetrahydropyrazolopyridines FI954991A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32643494A 1994-10-20 1994-10-20

Publications (2)

Publication Number Publication Date
FI954991A0 FI954991A0 (en) 1995-10-19
FI954991A true FI954991A (en) 1996-04-21

Family

ID=23272184

Family Applications (1)

Application Number Title Priority Date Filing Date
FI954991A FI954991A (en) 1994-10-20 1995-10-19 Bicyclic tetrahydropyrazolopyridines

Country Status (16)

Country Link
EP (1) EP0787132A1 (en)
JP (1) JPH09511758A (en)
KR (1) KR970707124A (en)
CN (1) CN1050129C (en)
AU (1) AU702105B2 (en)
BR (1) BR9504491A (en)
CZ (1) CZ120097A3 (en)
FI (1) FI954991A (en)
HU (1) HUT77517A (en)
IL (1) IL115667A0 (en)
MX (1) MX9504422A (en)
NO (1) NO971811L (en)
NZ (1) NZ292991A (en)
PL (1) PL319758A1 (en)
WO (1) WO1996012720A1 (en)
ZA (1) ZA958839B (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP1147A (en) * 1996-05-03 2003-02-25 Pfizer Substituted indazole derivatives and related compounds.
CA2258728C (en) 1996-06-19 2011-09-27 Rhone Poulenc Rorer Limited Substituted azabicylic compounds and their use as inhibitors of the production of tnf and cyclic amp phosphodiesterase
TR199802685T2 (en) * 1996-06-25 1999-03-22 Pfizer Inc �kameli/katk�l� indazol t�revleri
DK0983249T3 (en) * 1997-05-08 2002-07-08 Pfizer Prod Inc Methods and intermediates for the preparation of substituted indazole derivatives
IL126745A (en) * 1997-11-04 2003-09-17 Pfizer Prod Inc Methods of preparing 4-cyano-4- (substituted indazole) cyclohexanecarboxylic acids useful as pde4 inhibitors
AU759711B2 (en) * 1998-12-23 2003-04-17 Bristol-Myers Squibb Holdings Ireland Unlimited Company Nitrogen containing heterobicycles as factor XA inhibitors
US6858616B2 (en) 1998-12-23 2005-02-22 Bristol-Myers Squibb Pharma Company Nitrogen containing heterobicycles as factor Xa inhibitors
US6326495B2 (en) 1999-04-30 2001-12-04 Pfizer Inc. Process for preparing 8-cyclopentyl-6-ethyl-3-[substituted]-5,8-dihydro-4H-1,2,3a,7,8-pentaaza-as-indacenes and intermediates useful therein
AU777012B2 (en) 1999-08-21 2004-09-30 Takeda Gmbh Synergistic combination of PDE inhibitors and beta 2 adrenoceptor agonist
EP1320531B1 (en) * 2000-08-10 2010-09-08 Pfizer Italia S.r.l. Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
US6998408B2 (en) 2001-03-23 2006-02-14 Bristol-Myers Squibb Pharma Company 6-5, 6-6, or 6-7 Heterobicycles as factor Xa inhibitors
CA2444571A1 (en) 2001-04-18 2002-10-31 Bristol-Myers Squibb Company 1, 4, 5, 6-tetrahydropyrazolo-¬3, 4-c|-pyridin-7-ones as factor xa inhi bitors
CA2441772A1 (en) 2001-04-18 2002-10-31 Bristol-Myers Squibb Company 1,4,5,6-tetrahydropyrazolo-¬3,4-c|-pyridin-7-ones as factor xa inhibitors
JP4196678B2 (en) * 2001-04-26 2008-12-17 味の素株式会社 Heterocyclic compounds
TWI331526B (en) 2001-09-21 2010-10-11 Bristol Myers Squibb Pharma Co Lactam-containing compounds and derivatives thereof as factor xa inhibitors
RU2345993C2 (en) 2001-09-21 2009-02-10 Бристол-Маерс Сквибб Компани LACTAM-CONTAINING COMPOUND AND ITS DERIVATIVES AS Xa FACTOR INHIBITORS
MXPA05000947A (en) * 2002-07-25 2005-05-16 Pharmacia Italia Spa Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them.
AR045037A1 (en) 2003-07-10 2005-10-12 Aventis Pharma Sa TETRAHIDRO-1H-PIRAZOLO [3,4-C] SUBSTITUTED PYRIDINS, COMPOSITIONS THAT CONTAIN THEM AND ITS USE.
FR2857363B1 (en) * 2003-07-10 2007-09-07 Aventis Pharma Sa SUBSTITUTED 4,5,6,7-TETRAHYDRO-1H-PYRAZOLO [3,4-C] PYRIDINES COMPOSITIONS CONTAINING SAME AND USE THEREOF
EA014906B1 (en) 2005-12-01 2011-02-28 Элан Фармасьютикалз, Инк. 5-(arylsulfonyl)-pyrazolopiperidines
US8598195B2 (en) 2008-04-30 2013-12-03 Fredrik Almqvist Peptidomimetic compounds
JP6062633B2 (en) 2009-01-28 2017-01-18 カラ セラピューティクス インコーポレイテッド Bicyclic pyrazoloheterocycles
US7741350B1 (en) 2009-01-28 2010-06-22 Cara Therapeutics, Inc. Bicyclic pyrazolo-heterocycles
AR100767A1 (en) 2014-06-06 2016-11-02 Biogen Ma Inc ATX MODULATING AGENTS
CN115043768A (en) * 2022-06-20 2022-09-13 新乡市润宇新材料科技有限公司 Method for synthesizing N-aryl pyrrolidine-2-ketone by acid-promoted ring opening of cyclopropyl

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3365459A (en) * 1964-09-08 1968-01-23 Ciba Geigy Corp Certain tetrahydro pyrazolo-pyridine and pyrazolo-piperidine derivatives
FR1463883A (en) * 1964-09-08 1966-07-22 Ciba Geigy Process for the preparation of bicyclic triaza-compounds
US3340269A (en) * 1964-09-08 1967-09-05 Ciba Geigy Corp 1-substituted 4-acyl-2, 3-dioxo-piperidine
EP0707585A1 (en) * 1993-07-06 1996-04-24 Pfizer Inc. Bicyclic tetrahydro pyrazolopyridines

Also Published As

Publication number Publication date
IL115667A0 (en) 1996-01-19
HUT77517A (en) 1998-05-28
WO1996012720A1 (en) 1996-05-02
CN1050129C (en) 2000-03-08
NO971811D0 (en) 1997-04-18
PL319758A1 (en) 1997-08-18
NZ292991A (en) 1999-02-25
NO971811L (en) 1997-06-18
AU702105B2 (en) 1999-02-11
CZ120097A3 (en) 1998-01-14
ZA958839B (en) 1997-04-21
MX9504422A (en) 1997-04-30
EP0787132A1 (en) 1997-08-06
BR9504491A (en) 1997-05-20
JPH09511758A (en) 1997-11-25
CN1161040A (en) 1997-10-01
AU3531795A (en) 1996-05-15
KR970707124A (en) 1997-12-01
FI954991A0 (en) 1995-10-19

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