FI953089A - Boorihaposta johdetut uudet peptidiyhdisteet, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset - Google Patents

Boorihaposta johdetut uudet peptidiyhdisteet, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset Download PDF

Info

Publication number
FI953089A
FI953089A FI953089A FI953089A FI953089A FI 953089 A FI953089 A FI 953089A FI 953089 A FI953089 A FI 953089A FI 953089 A FI953089 A FI 953089A FI 953089 A FI953089 A FI 953089A
Authority
FI
Finland
Prior art keywords
compounds
preparation
pharmaceutical compositions
boric acid
compositions containing
Prior art date
Application number
FI953089A
Other languages
English (en)
Swedish (sv)
Other versions
FI953089A0 (fi
Inventor
Nanteuil Guillaume De
Christine Lila
Philippe Gloanec
Michel Laubie
Tony Verbeuren
Serge Simonet
Alain Rupin
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of FI953089A0 publication Critical patent/FI953089A0/fi
Publication of FI953089A publication Critical patent/FI953089A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI953089A 1994-06-22 1995-06-21 Boorihaposta johdetut uudet peptidiyhdisteet, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset FI953089A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9407589A FR2721611B1 (fr) 1994-06-22 1994-06-22 Nouveaux dérivés peptidiques de l'acide boronique, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent .

Publications (2)

Publication Number Publication Date
FI953089A0 FI953089A0 (fi) 1995-06-21
FI953089A true FI953089A (fi) 1995-12-23

Family

ID=9464456

Family Applications (1)

Application Number Title Priority Date Filing Date
FI953089A FI953089A (fi) 1994-06-22 1995-06-21 Boorihaposta johdetut uudet peptidiyhdisteet, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset

Country Status (13)

Country Link
US (1) US5585360A (fi)
EP (1) EP0688788B1 (fi)
JP (1) JP2862496B2 (fi)
CN (1) CN1121077A (fi)
AT (1) ATE199910T1 (fi)
AU (1) AU686365B2 (fi)
CA (1) CA2152205A1 (fi)
DE (1) DE69520389D1 (fi)
FI (1) FI953089A (fi)
FR (1) FR2721611B1 (fi)
NO (1) NO952482L (fi)
NZ (1) NZ272401A (fi)
ZA (1) ZA955176B (fi)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6825169B1 (en) 1991-10-22 2004-11-30 Trustees Of Tufts College Inhibitors of dipeptidyl-aminopeptidase type IV
CA2143533A1 (en) * 1994-03-04 1995-09-05 Kenneth D. Kurz Antithrombotic agents
ZA951618B (en) * 1994-03-04 1996-08-27 Lilly Co Eli Antithrombotic agents
US5705487A (en) * 1994-03-04 1998-01-06 Eli Lilly And Company Antithrombotic agents
US5602101A (en) * 1994-03-04 1997-02-11 Eli Lilly And Company Antithrombotic agents
US5885967A (en) * 1994-03-04 1999-03-23 Eli Lilly And Company Antithrombotic agents
US5707966A (en) * 1994-03-04 1998-01-13 Eli Lilly And Company Antithrombotic agents
US5726159A (en) * 1994-03-04 1998-03-10 Eli Lilly And Company Antithrombotic agents
US5914319A (en) * 1995-02-27 1999-06-22 Eli Lilly And Company Antithrombotic agents
US5710130A (en) * 1995-02-27 1998-01-20 Eli Lilly And Company Antithrombotic agents
US5811402A (en) * 1996-03-22 1998-09-22 Eli Lilly And Company Antithrombotic diamides
US5965532A (en) 1996-06-28 1999-10-12 Trustees Of Tufts College Multivalent compounds for crosslinking receptors and uses thereof
US6194435B1 (en) 1996-10-11 2001-02-27 Cor Therapeutics, Inc. Lactams as selective factor Xa inhibitors
US6262047B1 (en) 1996-10-11 2001-07-17 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6369080B2 (en) 1996-10-11 2002-04-09 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6063794A (en) 1996-10-11 2000-05-16 Cor Therapeutics Inc. Selective factor Xa inhibitors
WO1998046628A1 (en) * 1997-04-14 1998-10-22 Cor Therapeutics, Inc. SELECTIVE FACTOR Xa INHIBITORS
WO1998046626A1 (en) 1997-04-14 1998-10-22 Cor Therapeutics, Inc. SELECTIVE FACTOR Xa INHIBITORS
EP0977773A1 (en) 1997-04-14 2000-02-09 Cor Therapeutics, Inc. SELECTIVE FACTOR Xa INHIBITORS
US6100234A (en) 1997-05-07 2000-08-08 Tufts University Treatment of HIV
US6040145A (en) 1997-05-07 2000-03-21 Tufts University Potentiation of the immune response
US6333321B1 (en) 1997-08-11 2001-12-25 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6228854B1 (en) 1997-08-11 2001-05-08 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6218382B1 (en) 1997-08-11 2001-04-17 Cor Therapeutics, Inc Selective factor Xa inhibitors
ATE357509T1 (de) 1997-09-29 2007-04-15 Point Therapeutics Inc Stimulierung von hämatopoietischen zellen im vitro
EP1075266A1 (en) 1998-05-04 2001-02-14 Point Therapeutics, Inc. Hematopoietic stimulation
US6890904B1 (en) 1999-05-25 2005-05-10 Point Therapeutics, Inc. Anti-tumor agents
JP4416501B2 (ja) * 2001-05-30 2010-02-17 ノバルティス アクチエンゲゼルシャフト ２−｛［ｎ−（２−アミノ−３−（ヘテロアリールまたはアリール）プロピオニル）−アミノアシル］−アミノ｝−アルキルボロン酸誘導体
US7112572B2 (en) * 2002-09-09 2006-09-26 Trigen Limited Multivalent metal salts of boronic acids
PT1396270E (pt) 2002-09-09 2006-08-31 Trigen Ltd Processo para a preparacao de compostos uteisncomo intermidiarios.
US20050176651A1 (en) * 2002-09-09 2005-08-11 Trigen Limited Peptide boronic acids useful in making salts thereof
US20050282757A1 (en) * 2002-09-09 2005-12-22 Trigen Limited Peptide boronic acid compounds useful in anticoagulation
US20050119226A1 (en) * 2003-09-09 2005-06-02 Trigen Limited Methods for synthesizing organoboronic compounds and products thereof
US20060084592A1 (en) * 2002-09-09 2006-04-20 Trigen Limited Peptide boronic acid inhibitors
GB0405272D0 (en) * 2004-03-09 2004-04-21 Trigen Ltd Compounds
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5187157A (en) * 1987-06-05 1993-02-16 Du Pont Merck Pharmaceutical Company Peptide boronic acid inhibitors of trypsin-like proteases
US5288707A (en) * 1990-08-13 1994-02-22 Sandoz Ltd. Borolysine peptidomimetics
GB9017694D0 (en) * 1990-08-13 1990-09-26 Sandoz Ltd Improvements in or relating to organic chemistry
GB9024129D0 (en) * 1990-11-06 1990-12-19 Thrombosis Research Trust Inhibitors and substrates of thrombin
FR2701951B1 (fr) * 1993-02-24 1995-06-09 Adir Nouveaux derives peptidiques de l'acide boronique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
IL109319A0 (en) * 1993-04-27 1994-07-31 Du Pont Merck Pharma Amidino and guanidino substituted boronic acid compounds
IL111175A0 (en) * 1993-10-07 1994-12-29 Du Pont Merck Pharma Electrophilic peptide analogs as inhibitors of trypsin-like serine proteases and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0688788B1 (fr) 2001-03-21
CA2152205A1 (fr) 1995-12-23
NO952482L (no) 1995-12-27
JP2862496B2 (ja) 1999-03-03
JPH083187A (ja) 1996-01-09
DE69520389D1 (de) 2001-04-26
NZ272401A (en) 1996-05-28
US5585360A (en) 1996-12-17
AU686365B2 (en) 1998-02-05
EP0688788A1 (fr) 1995-12-27
FI953089A0 (fi) 1995-06-21
ATE199910T1 (de) 2001-04-15
ZA955176B (en) 1996-02-08
CN1121077A (zh) 1996-04-24
NO952482D0 (no) 1995-06-21
AU2180195A (en) 1996-01-04
FR2721611A1 (fr) 1995-12-29
FR2721611B1 (fr) 1996-09-27

Similar Documents

Publication Publication Date Title
FI953089A (fi) Boorihaposta johdetut uudet peptidiyhdisteet, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
FI955024A (fi) Uudet piperidiiniyhdisteet, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
HUT74093A (en) Oxazolidinone derivatives as adhesion-receptor antagonists, pharmaceutical compositions containing them and process for their preparation
DE3874844D1 (de) Mehrkernige substituierte komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel.
FR2687402B1 (fr) Nouveaux azaindoles, procedes de preparation et medicaments les contenant.
NZ324007A (en) Quinazoline derivatives susbtituted by a phenyl and medicaments
FI941987A0 (fi) Uudet aminohappojohdannaiset, menetelmät niiden valmistamiseksi ja näitä yhdisteitä sisältävät farmaseuttiset koostumukset
IL71324A (en) N-phenyl-n'-cycloalkylalkanoyl-piperazines,their production and pharmaceutical compositions containing them
IL88784A (en) Substituted 6-phenyldihydro-3-(2h)- pyridazinones, a process for their preparation and pharmaceutical preparations containing these compounds
PT96788A (pt) Processo de preparacao de compostos de ureia substituida e de composicoes farmaceuticas
ES8606363A1 (es) Un procedimiento de preparar derivados de acido 1-destia-2- tiacefalosporanico
ES8101589A1 (es) Un procedimiento para la preparacion de nuevos compuestos iminicos heterociclicos.
ES8604723A1 (es) Un procedimiento para la preparacion de derivados de piperi-dina
ES8604600A1 (es) Un metodo para la preparacion de derivados penem
FI950681A0 (fi) Uudent akronysiinianalogit, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
YU30299A (sh) Novi inhibitori farnezil-transferaze,njihovo dobijanje, farmaceutske smeše koje ih sadrže i njihova primena za dobijanje lekova
ATE152107T1 (de) 3,9-disubstituierte-spiro (5.5)undecane mit cardiovasculaire wirkung, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische präparate
AU4816496A (en) New thiophene compounds, process for the preparation thereof, and pharmaceutical compositions containing them