FI952733A0 - Spirofuranone derivatives and their use in neurodegenerative disorders - Google Patents

Spirofuranone derivatives and their use in neurodegenerative disorders

Info

Publication number
FI952733A0
FI952733A0 FI952733A FI952733A FI952733A0 FI 952733 A0 FI952733 A0 FI 952733A0 FI 952733 A FI952733 A FI 952733A FI 952733 A FI952733 A FI 952733A FI 952733 A0 FI952733 A0 FI 952733A0
Authority
FI
Finland
Prior art keywords
spirofuranone
derivatives
neurodegenerative disorders
neurodegenerative
disorders
Prior art date
Application number
FI952733A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI952733A (en
Inventor
Alexander Kover
Iii James Loch
George Mullen
Edwin Shen-Chou Wu
Original Assignee
Fisons Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929225498A external-priority patent/GB9225498D0/en
Priority claimed from GB929225497A external-priority patent/GB9225497D0/en
Priority claimed from GB939316531A external-priority patent/GB9316531D0/en
Application filed by Fisons Corp filed Critical Fisons Corp
Publication of FI952733A publication Critical patent/FI952733A/en
Publication of FI952733A0 publication Critical patent/FI952733A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
FI952733A 1992-12-05 1995-06-05 Spirofuranone derivatives and their use in neurodegenerative disorders FI952733A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB929225498A GB9225498D0 (en) 1992-12-05 1992-12-05 Pharmacologically active compounds
GB929225497A GB9225497D0 (en) 1992-12-05 1992-12-05 Pharmacologically active compounds
GB939316531A GB9316531D0 (en) 1993-08-10 1993-08-10 Pharmacologically active compounds
PCT/GB1993/002500 WO1994013678A1 (en) 1992-12-05 1993-12-06 Spirofuranone derivatives and their use in the treatment of neurodegenerative disorders

Publications (2)

Publication Number Publication Date
FI952733A FI952733A (en) 1995-06-05
FI952733A0 true FI952733A0 (en) 1995-06-05

Family

ID=27266497

Family Applications (1)

Application Number Title Priority Date Filing Date
FI952733A FI952733A0 (en) 1992-12-05 1995-06-05 Spirofuranone derivatives and their use in neurodegenerative disorders

Country Status (10)

Country Link
EP (1) EP0672046A1 (en)
JP (1) JPH08503955A (en)
KR (1) KR950704322A (en)
AU (1) AU5655394A (en)
CA (1) CA2150947A1 (en)
FI (1) FI952733A0 (en)
IL (1) IL107881A0 (en)
MX (1) MX9307679A (en)
NO (1) NO952194L (en)
WO (1) WO1994013678A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1021446A1 (en) * 1997-01-27 2000-07-26 Warner-Lambert Company Single pot process for producing (z)-azabicyclo oxime ethers
TWI243173B (en) 1999-11-17 2005-11-11 Akzo Nobel Nv Spiro[2H-1-benzopyran-2,4'-piperidine] derivatives
WO2005068462A1 (en) * 2004-01-08 2005-07-28 F. Hoffmann-La Roche Ag Diaza-spiropiperidine derivatives as inhibitors of transporter 1 and glycine transporter 2

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075317A (en) * 1989-06-21 1991-12-24 Fisons Corporation Spirofurane derivatives
JPH03153690A (en) * 1989-11-10 1991-07-01 Yamanouchi Pharmaceut Co Ltd Heterocyclic spiro derivative and production thereof
IE914238A1 (en) * 1990-12-19 1992-07-01 Fisons Corp Novel spirofurane derivatives

Also Published As

Publication number Publication date
IL107881A0 (en) 1994-04-12
KR950704322A (en) 1995-11-17
WO1994013678A1 (en) 1994-06-23
MX9307679A (en) 1994-06-30
EP0672046A1 (en) 1995-09-20
NO952194D0 (en) 1995-06-02
FI952733A (en) 1995-06-05
NO952194L (en) 1995-06-02
CA2150947A1 (en) 1994-06-23
JPH08503955A (en) 1996-04-30
AU5655394A (en) 1994-07-04

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Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: ASTRA AB

FD Application lapsed