FI950197L - 4-(4-fluorofenyylimetyyli)-piperidiini, jolla on sigma ja D2-reseptori affiniteetti - Google Patents

4-(4-fluorofenyylimetyyli)-piperidiini, jolla on sigma ja D2-reseptori affiniteetti Download PDF

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Publication number
FI950197L
FI950197L FI950197A FI950197A FI950197L FI 950197 L FI950197 L FI 950197L FI 950197 A FI950197 A FI 950197A FI 950197 A FI950197 A FI 950197A FI 950197 L FI950197 L FI 950197L
Authority
FI
Finland
Prior art keywords
fluorophenylmethyl
piperidine
sigma
receptor affinity
affinity
Prior art date
Application number
FI950197A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI950197A7 (fi
FI950197A0 (fi
Inventor
Rafael Foquet
Jordi Bolos
Aurelio Sacristan
Jose Ortiz
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Int filed Critical Ferrer Int
Publication of FI950197A7 publication Critical patent/FI950197A7/fi
Publication of FI950197A0 publication Critical patent/FI950197A0/fi
Publication of FI950197L publication Critical patent/FI950197L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI950197A 1993-05-18 1994-05-17 4-(4-fluorofenyylimetyyli)-piperidiini, jolla on sigma ja D2-reseptori affiniteetti FI950197L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES09301062A ES2066721B1 (es) 1993-05-18 1993-05-18 Nuevos compuestos derivados de la piridina 1,4-disustituida.
PCT/EP1994/001594 WO1994026712A1 (en) 1993-05-18 1994-05-17 4-(4-fluorophenylmethyl)-piperidines having sigma and d2-receptor affinity

Publications (3)

Publication Number Publication Date
FI950197A7 FI950197A7 (fi) 1995-01-17
FI950197A0 FI950197A0 (fi) 1995-01-17
FI950197L true FI950197L (fi) 1995-01-17

Family

ID=8281846

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950197A FI950197L (fi) 1993-05-18 1994-05-17 4-(4-fluorofenyylimetyyli)-piperidiini, jolla on sigma ja D2-reseptori affiniteetti

Country Status (12)

Country Link
EP (1) EP0651744A1 (cs)
JP (1) JPH07509255A (cs)
KR (1) KR950702535A (cs)
AU (1) AU675332B2 (cs)
CA (1) CA2140260A1 (cs)
ES (1) ES2066721B1 (cs)
FI (1) FI950197L (cs)
NO (1) NO301638B1 (cs)
NZ (1) NZ267100A (cs)
TW (1) TW252975B (cs)
WO (1) WO1994026712A1 (cs)
ZA (1) ZA943036B (cs)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HN1999000149A (es) * 1998-09-09 2000-01-12 Pfizer Prod Inc Derivados de 4,4-biarilpiperidina

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3576810A (en) * 1968-06-20 1971-04-27 Robins Co Inc A H 1-substituted-3-(-4)-aroylpiperidines
SE7409245L (cs) * 1973-07-19 1975-01-20 Robins Co Inc A H
US3956296A (en) * 1974-12-11 1976-05-11 A. H. Robins Company, Incorporated 1-Substituted-4-benzylpiperidines
DK623586A (da) * 1985-12-27 1987-06-28 Eisai Co Ltd Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne
FR2681319B1 (fr) * 1991-09-12 1995-02-17 Synthelabo Derives de 1-(phenoxyalkyl)piperidine, leur preparation et leur application en therapeutique.
ES2060547B1 (es) * 1992-06-04 1995-06-16 Ferrer Int Mejoras en el objeto de la patente de invencion n/ 9201158 que se refiere a "procedimiento de obtencion de nuevos derivados de la 4-bencilpiperidina".

Also Published As

Publication number Publication date
NZ267100A (en) 1996-09-25
NO950062D0 (no) 1995-01-06
FI950197A7 (fi) 1995-01-17
WO1994026712A1 (en) 1994-11-24
KR950702535A (ko) 1995-07-29
ES2066721A1 (es) 1995-03-01
ZA943036B (en) 1995-05-02
TW252975B (cs) 1995-08-01
FI950197A0 (fi) 1995-01-17
EP0651744A1 (en) 1995-05-10
NO950062L (no) 1995-01-06
ES2066721B1 (es) 1996-02-16
CA2140260A1 (en) 1994-11-24
AU675332B2 (en) 1997-01-30
NO301638B1 (no) 1997-11-24
AU6928494A (en) 1994-12-12
JPH07509255A (ja) 1995-10-12

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