FI925518A - Förfarande för framställning av terapeutiskt aktiva 1-piperidinylalkanoylarylsulfonamidderivat - Google Patents

Förfarande för framställning av terapeutiskt aktiva 1-piperidinylalkanoylarylsulfonamidderivat Download PDF

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Publication number
FI925518A
FI925518A FI925518A FI925518A FI925518A FI 925518 A FI925518 A FI 925518A FI 925518 A FI925518 A FI 925518A FI 925518 A FI925518 A FI 925518A FI 925518 A FI925518 A FI 925518A
Authority
FI
Finland
Prior art keywords
piperidinylalkanoylarylsulfonamide
derivatives
preparation
therapeutically active
alkanoylarylsulfonamides
Prior art date
Application number
FI925518A
Other languages
English (en)
Finnish (fi)
Other versions
FI925518A0 (sv
FI98456B (sv
FI98456C (sv
Inventor
Albert A Carr
Richard C Dage
Thaddeus R Nieduzak
John E Koerner
Tung Li
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of FI925518A publication Critical patent/FI925518A/sv
Publication of FI925518A0 publication Critical patent/FI925518A0/sv
Publication of FI98456B publication Critical patent/FI98456B/sv
Application granted granted Critical
Publication of FI98456C publication Critical patent/FI98456C/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
FI925518A 1990-06-07 1992-12-04 Förfarande för framställning av terapeutiskt aktiva 1-piperidinylalkanoylarylsulfonamidderivat FI98456C (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US53478490A 1990-06-07 1990-06-07
US53478490 1990-06-07
PCT/US1991/003323 WO1991018603A1 (en) 1990-06-07 1991-05-15 1-pyperidinyl alkanoylarylsulfonamide derivatives
US9103323 1991-05-15

Publications (4)

Publication Number Publication Date
FI925518A true FI925518A (sv) 1992-12-04
FI925518A0 FI925518A0 (sv) 1992-12-04
FI98456B FI98456B (sv) 1997-03-14
FI98456C FI98456C (sv) 1997-06-25

Family

ID=24131528

Family Applications (1)

Application Number Title Priority Date Filing Date
FI925518A FI98456C (sv) 1990-06-07 1992-12-04 Förfarande för framställning av terapeutiskt aktiva 1-piperidinylalkanoylarylsulfonamidderivat

Country Status (14)

Country Link
EP (1) EP0532629B1 (sv)
JP (1) JP3032294B2 (sv)
KR (1) KR100200461B1 (sv)
AT (1) ATE144899T1 (sv)
AU (1) AU650031B2 (sv)
CA (1) CA2084082C (sv)
DE (1) DE69123052T2 (sv)
DK (1) DK0532629T3 (sv)
ES (1) ES2096651T3 (sv)
FI (1) FI98456C (sv)
GR (1) GR3022327T3 (sv)
HU (1) HU214587B (sv)
NO (1) NO179205C (sv)
WO (1) WO1991018603A1 (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995000481A1 (en) * 1993-06-23 1995-01-05 Merrell Dow Pharmaceuticals Inc. Piperidin-1-yl-2,2-dialkylpropanonearylsulfonamide derivatives
EP0661266A1 (en) * 1993-12-27 1995-07-05 Toa Eiyo Ltd. Substituted cyclic amine compounds as 5HT2 antagonists
TWI249526B (en) * 1998-03-13 2006-02-21 Aventis Pharma Inc Novel processes for the preparation of (R)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
US6713627B2 (en) 1998-03-13 2004-03-30 Aventis Pharmaceuticals Inc. Processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
HUP0204496A3 (en) 2000-01-20 2004-07-28 Eisai Co Ltd Novel piperidine compounds and pharmaceutical compositions containing the same and process for preparation the same
RU2333200C2 (ru) 2003-03-07 2008-09-10 Астеллас Фарма Инк. Азотсодержащие гетероциклические производные, содержащие 2,6-дизамещенный стирил
JP5400843B2 (ja) * 2011-09-06 2014-01-29 本田技研工業株式会社 車両構造

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982001873A1 (en) * 1980-12-05 1982-06-10 Takeda Chemical Industries Ltd 1-sulfo-2-oxoazetidine derivatives and process for their preparation
FR2581993B1 (fr) * 1985-05-14 1988-03-18 Synthelabo Derives de (benzoyl-4 piperidino)-2 phenyl-1 alcanols, leur preparation et leur application en therapeutique
PH23283A (en) * 1986-02-26 1989-06-30 Eisai Co Ltd Piperidine derivative, pharmaceutical composition containing the same and method of use thereof
PH25458A (en) * 1987-08-24 1991-07-01 Eisai Co Ltd Piperidine derivatives, therapeutic, preventive agents
US5093341A (en) * 1987-12-17 1992-03-03 Merrell Dow Pharmaceuticals Inc. N-aralkyl piperidine derivatives useful as antithrombolytic agents
US5064838A (en) * 1988-01-21 1991-11-12 Merrell Dow Pharmaceuticals 1,4-disubstituted-piperidinyl compounds as pain relievers
NZ236501A (en) * 1989-12-21 1992-12-23 Merrell Dow Pharma Piperidine derivatives and antithrombotic compositions

Also Published As

Publication number Publication date
EP0532629B1 (en) 1996-11-06
JP3032294B2 (ja) 2000-04-10
NO179205B (no) 1996-05-20
DK0532629T3 (da) 1996-11-25
HU9203856D0 (en) 1993-04-28
NO924694L (no) 1992-12-04
GR3022327T3 (en) 1997-04-30
ATE144899T1 (de) 1996-11-15
CA2084082A1 (en) 1991-12-08
FI925518A0 (sv) 1992-12-04
HU214587B (hu) 1998-04-28
JPH06501242A (ja) 1994-02-10
AU7992291A (en) 1991-12-31
HUT64517A (en) 1994-01-28
DE69123052D1 (de) 1996-12-12
DE69123052T2 (de) 1997-03-06
KR930700441A (ko) 1993-03-15
EP0532629A1 (en) 1993-03-24
AU650031B2 (en) 1994-06-09
EP0532629A4 (sv) 1994-03-09
FI98456B (sv) 1997-03-14
FI98456C (sv) 1997-06-25
NO924694D0 (no) 1992-12-04
KR100200461B1 (ko) 1999-06-15
NO179205C (no) 1996-08-28
ES2096651T3 (es) 1997-03-16
CA2084082C (en) 2002-03-19
WO1991018603A1 (en) 1991-12-12

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Owner name: AVENTIS INC.

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Owner name: AVENTISUB II INC.

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