FI923088A - Oktadekyl-(2-(n-metylpiperidino)-etyl)-fosfat och foerfarande foer dess framstaellning - Google Patents
Oktadekyl-(2-(n-metylpiperidino)-etyl)-fosfat och foerfarande foer dess framstaellning Download PDFInfo
- Publication number
- FI923088A FI923088A FI923088A FI923088A FI923088A FI 923088 A FI923088 A FI 923088A FI 923088 A FI923088 A FI 923088A FI 923088 A FI923088 A FI 923088A FI 923088 A FI923088 A FI 923088A
- Authority
- FI
- Finland
- Prior art keywords
- methylpiperidino
- octadecyl
- phosphate
- ethyl
- overfining
- Prior art date
Links
- CUQJLYFFQBHUGW-UHFFFAOYSA-N 2-(1-methylpiperidin-1-ium-1-yl)ethyl octadecyl phosphate Chemical compound CCCCCCCCCCCCCCCCCCOP([O-])(=O)OCC[N+]1(C)CCCCC1 CUQJLYFFQBHUGW-UHFFFAOYSA-N 0.000 title 1
- 230000000118 anti-neoplastic effect Effects 0.000 abstract 1
- ZJXZSIYSNXKHEA-UHFFFAOYSA-N ethyl dihydrogen phosphate Chemical compound CCOP(O)(O)=O ZJXZSIYSNXKHEA-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4122140 | 1991-07-04 | ||
| DE4122140 | 1991-07-04 | ||
| DE4129364 | 1991-09-04 | ||
| DE4129364 | 1991-09-04 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI923088A0 FI923088A0 (fi) | 1992-07-03 |
| FI923088A true FI923088A (fi) | 1993-01-05 |
| FI108035B FI108035B (fi) | 2001-11-15 |
Family
ID=25905206
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI923088A FI108035B (fi) | 1991-07-04 | 1992-07-03 | Menetelmä terapeuttisesti käyttökelpoisen oktadekyyli-[2-(N-metyylipiperidino)etyyli]fosfaatin valmistamiseksi ja menetelmä sen puhdistamiseksi |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5219866A (fi) |
| EP (1) | EP0521353B1 (fi) |
| JP (1) | JP3176720B2 (fi) |
| KR (1) | KR100255436B1 (fi) |
| CN (1) | CN1030658C (fi) |
| AT (1) | ATE136783T1 (fi) |
| AU (1) | AU651224B2 (fi) |
| CA (1) | CA2073146C (fi) |
| DE (2) | DE4219972A1 (fi) |
| DK (1) | DK0521353T3 (fi) |
| EG (1) | EG20082A (fi) |
| ES (1) | ES2086026T3 (fi) |
| FI (1) | FI108035B (fi) |
| GR (1) | GR3019776T3 (fi) |
| HU (2) | HUT61561A (fi) |
| IE (1) | IE73200B1 (fi) |
| IL (1) | IL102380A (fi) |
| NO (1) | NO303939B1 (fi) |
| PL (3) | PL173794B1 (fi) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE516036T1 (de) * | 2002-07-30 | 2011-07-15 | Fterna Zentaris Gmbh | Anwendung von alkylphosphocholinen in kombination mit antitumormedikamenten |
| US8383605B2 (en) * | 2002-07-30 | 2013-02-26 | Aeterna Zentaris Gmbh | Use of alkylphosphocholines in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals |
| UA99434C2 (ru) * | 2005-12-19 | 2012-08-27 | Аетерна Центаріс Гмбх | Применение производных алкилфосфолипидов со сниженной цитотоксичностью |
| JP5232009B2 (ja) * | 2005-12-19 | 2013-07-10 | エテルナ ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 低減された細胞毒性を有するアルキルリン脂質誘導体並びにそれらの使用 |
| JP5068630B2 (ja) * | 2007-11-15 | 2012-11-07 | オルガノ株式会社 | アルコール含有溶液中のアルデヒド化合物の除去方法及び該方法により精製された醸造酒 |
| CA2794513A1 (en) | 2010-03-31 | 2011-10-06 | Aeterna Zentaris Gmbh | Perifosine and capecitabine as a combined treatment for cancer |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU301951A1 (ru) * | 1970-06-01 | 1973-04-05 | В. А. Чернов, Т. С. Сафонова, Н. В. Сазонов, А. А. Кропачева, | Лекарственное средство |
| JPS5984824A (ja) * | 1982-11-08 | 1984-05-16 | Takeda Chem Ind Ltd | 抗腫瘍剤 |
| DE59208905D1 (de) * | 1991-07-04 | 1997-10-23 | Asta Medica Ag | Verfahren zur Herstellung von Alkylphosphocholinen und Reinherstellung derselben |
-
1992
- 1992-06-19 DE DE4219972A patent/DE4219972A1/de not_active Withdrawn
- 1992-06-19 AT AT92110347T patent/ATE136783T1/de not_active IP Right Cessation
- 1992-06-19 DE DE59205998T patent/DE59205998D1/de not_active Expired - Fee Related
- 1992-06-19 ES ES92110347T patent/ES2086026T3/es not_active Expired - Lifetime
- 1992-06-19 EP EP92110347A patent/EP0521353B1/de not_active Expired - Lifetime
- 1992-06-19 DK DK92110347.9T patent/DK0521353T3/da active
- 1992-07-01 EG EG34592A patent/EG20082A/xx active
- 1992-07-01 US US07/907,025 patent/US5219866A/en not_active Expired - Lifetime
- 1992-07-02 PL PL92311787A patent/PL173794B1/pl not_active IP Right Cessation
- 1992-07-02 IL IL10238092A patent/IL102380A/en not_active IP Right Cessation
- 1992-07-02 PL PL92311788A patent/PL173869B1/pl not_active IP Right Cessation
- 1992-07-02 PL PL92295128A patent/PL173905B1/pl not_active IP Right Cessation
- 1992-07-03 HU HU9202232A patent/HUT61561A/hu unknown
- 1992-07-03 KR KR1019920011821A patent/KR100255436B1/ko not_active IP Right Cessation
- 1992-07-03 FI FI923088A patent/FI108035B/fi active
- 1992-07-03 AU AU19435/92A patent/AU651224B2/en not_active Ceased
- 1992-07-03 NO NO922642A patent/NO303939B1/no unknown
- 1992-07-03 JP JP17691592A patent/JP3176720B2/ja not_active Expired - Fee Related
- 1992-07-03 CN CN92105452A patent/CN1030658C/zh not_active Expired - Fee Related
- 1992-07-03 IE IE922183A patent/IE73200B1/en not_active IP Right Cessation
- 1992-07-03 CA CA002073146A patent/CA2073146C/en not_active Expired - Fee Related
-
1995
- 1995-06-16 HU HU95P/P00233P patent/HU211483A9/hu unknown
-
1996
- 1996-04-29 GR GR960401156T patent/GR3019776T3/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69101931D1 (de) | Pharmazeutische Zusammensetzung. | |
| FI901102A0 (fi) | Farmaceutiska kompositioner. | |
| FI922364A0 (fi) | Farmaceutiska kompositioner. | |
| NO900612D0 (no) | Preservativ for vandige sammensetninger. | |
| DE69111681D1 (de) | Elektronenoptische Messeinrichtung. | |
| ITTO910567A0 (it) | Derivati carbostirilici. | |
| FI923088A (fi) | Oktadekyl-(2-(n-metylpiperidino)-etyl)-fosfat och foerfarande foer dess framstaellning | |
| IT7925706A0 (it) | Uso di glicerilfosforilderivati nella terapia di dislipemie ed epatiti, e composizioni farmaceutiche relative. | |
| IT1240318B (it) | Formulazione emulsionante perfezionata | |
| IT8024150A0 (it) | Derivati di alovincamone eprocedimento per la loro preparazione. | |
| FI923371A0 (fi) | En farmaceutisk formulation. | |
| DE68908414D1 (de) | Pharmazeutische zusammensetzungen fuer die reizung eines immunostimulierenden effektes. | |
| MA22143A1 (fr) | Derives de 1,5 benzothiazepinone, leurs preparations et leur application | |
| DE69003056D1 (de) | S-Alkylthiopropionsäuren und deren Derivate. | |
| MX9102662A (es) | Lamina de alta consistencia. | |
| ES1008860Y (es) | Tenaza perfeccionada. | |
| DE69130099D1 (de) | Antineoplastischer wirkstoff | |
| DE69008686D1 (de) | Pulverisiermühle. | |
| MX9204164A (es) | Composicion farmaceutica que comprende arndh. | |
| SE8503513L (sv) | Farmaceutiska och kosmetiska kompositioner, vilka som verksam bestandsdel innehaller acetyl-10-triacetoxi-1,8,9-antracen | |
| ES1014445Y (es) | Calcetin perfeccionado. | |
| DE69005302D1 (de) | Papierleimungszusammensetzungen. | |
| ES1011290Y (es) | Caballete perfeccionado. | |
| KR900014543U (ko) | 맥반석 정수기 | |
| NO911441L (no) | Regioselektiv formyleringsfremgangsmaate. |