FI91155B - Menetelmä uuden, terapeuttisesti käyttökelpoisen 9-(2-hydroksietoksimetyyli)guaniiniesterin valmistamiseksi - Google Patents

Menetelmä uuden, terapeuttisesti käyttökelpoisen 9-(2-hydroksietoksimetyyli)guaniiniesterin valmistamiseksi

Info

Publication number
FI91155B
FI91155B FI893408A FI893408A FI91155B FI 91155 B FI91155 B FI 91155B FI 893408 A FI893408 A FI 893408A FI 893408 A FI893408 A FI 893408A FI 91155 B FI91155 B FI 91155B
Authority
FI
Finland
Prior art keywords
preparation
ester
hydroxyethoxymethyl
guanine
therapeutically useful
Prior art date
Application number
FI893408A
Other languages
English (en)
Swedish (sv)
Other versions
FI893408A0 (fi
FI91155C (fi
FI893408A (fi
Inventor
Lilia Marie Beauchamp
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of FI893408A0 publication Critical patent/FI893408A0/fi
Publication of FI893408A publication Critical patent/FI893408A/fi
Application granted granted Critical
Publication of FI91155B publication Critical patent/FI91155B/fi
Publication of FI91155C publication Critical patent/FI91155C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oncology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
FI893408A 1988-07-14 1989-07-13 Menetelmä uuden, terapeuttisesti käyttökelpoisen 9-(2-hydroksietoksimetyyli)guaniiniesterin valmistamiseksi FI91155C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888816760A GB8816760D0 (en) 1988-07-14 1988-07-14 Therapeutic compounds
GB8816760 1988-07-14

Publications (4)

Publication Number Publication Date
FI893408A0 FI893408A0 (fi) 1989-07-13
FI893408A FI893408A (fi) 1990-01-15
FI91155B true FI91155B (fi) 1994-02-15
FI91155C FI91155C (fi) 1994-05-25

Family

ID=10640438

Family Applications (1)

Application Number Title Priority Date Filing Date
FI893408A FI91155C (fi) 1988-07-14 1989-07-13 Menetelmä uuden, terapeuttisesti käyttökelpoisen 9-(2-hydroksietoksimetyyli)guaniiniesterin valmistamiseksi

Country Status (19)

Country Link
US (1) US5079252A (fi)
EP (1) EP0351215B1 (fi)
JP (1) JP2791116B2 (fi)
KR (1) KR900001697A (fi)
AT (1) ATE139535T1 (fi)
AU (1) AU622686B2 (fi)
CA (1) CA1331611C (fi)
DE (1) DE68926697T2 (fi)
DK (1) DK347289A (fi)
FI (1) FI91155C (fi)
GB (1) GB8816760D0 (fi)
HU (1) HU210425B (fi)
IE (1) IE892261L (fi)
IL (1) IL90959A (fi)
MY (1) MY104124A (fi)
NZ (1) NZ229929A (fi)
PH (1) PH26913A (fi)
PT (1) PT91153B (fi)
ZA (1) ZA895345B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162459A (en) * 1995-02-24 2000-12-19 National Science Council Acyclovir transdermal delivery system
DE19536164A1 (de) * 1995-09-28 1997-04-03 Boehringer Ingelheim Kg Verbessertes Verfahren zur Herstellung von 9-[(2-Hyroxyethoxy)methyl]guanin (Acyclovir)
US5677308A (en) * 1996-12-19 1997-10-14 Lerner; A. Martin Method for alleviating spasmodic torticollis
US5872123A (en) * 1997-02-18 1999-02-16 Lerner; A. Martin Method for diagnosing and alleviating the symptoms of chronic fatigue syndrome
US6537997B1 (en) 1997-02-18 2003-03-25 A. Martin Lerner Method for diagnosing and alleviating the symptoms of chronic fatigue syndrome
US6399622B1 (en) 1997-02-18 2002-06-04 A. Martin Lerner Method for diagnosing and alleviating the symptoms of chronic fatigue syndrome
US6107303A (en) * 1999-03-15 2000-08-22 Demarco; Charlene C. Treatment of Epstein Barr infection
US20030212051A1 (en) * 2001-04-06 2003-11-13 Polli James E Bile acid containing prodrugs with enhanced bioavailabilty
WO2013011336A2 (en) 2011-07-15 2013-01-24 Budapesti Műszaki és Gazdaságtudományi Egyetem Data input device
US20140100238A1 (en) 2012-10-04 2014-04-10 Ohio State University Method of diagnosing and treating epstein barr virus-based myalgic encephalomyelitis chronic fatigue syndrome patients

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199574A (en) * 1974-09-02 1980-04-22 Burroughs Wellcome Co. Methods and compositions for treating viral infections and guanine acyclic nucleosides
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
GB1561380A (en) * 1976-03-01 1980-02-20 Wellcome Found Esters of hydroxyalkoxyalkyl purines their preparation and pharmaceutical compositions containing them
US4146715A (en) * 1975-08-27 1979-03-27 Burroughs Wellcome Co. 2-amido-9-(2-acyloxyethoxymethyl)hypoxanthines
AU515553B2 (en) * 1976-03-01 1981-04-09 The Wellcome Foundation Limited Purine derivatives
US4287188A (en) * 1977-02-24 1981-09-01 Burroughs Wellcome Co. Purine derivatives
US4544634A (en) * 1982-10-14 1985-10-01 Burroughs Wellcome Co. Method of producing acyclovir
US4609662A (en) * 1982-10-14 1986-09-02 Burroughs Wellcome Co. Method for using purine derivatives
US4695570A (en) * 1982-10-14 1987-09-22 Burroughs Wellcome Co. Antiviral compound use
US4745119A (en) * 1982-10-14 1988-05-17 Burroughs Wellcome Co. Method for using purine derivatives
US4612314A (en) * 1982-12-22 1986-09-16 Syntex (U.S.A.) Inc. Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent
IE842642L (en) * 1983-10-31 1985-04-30 Harvard College Purine Derivatives
IL74881A0 (en) * 1984-04-13 1985-07-31 Wellcome Found Purine derivatives,their preparation and pharmaceutical compositions containing them
DE3889248T2 (de) * 1987-05-04 1994-11-17 Kemijski Inst Verfahren zu Herstellung von Purinverbindungen.
AP160A (en) * 1987-08-15 1991-11-18 The Wellcome Foundation Ltd Therapeutic acyclic nucleosides.

Also Published As

Publication number Publication date
GB8816760D0 (en) 1988-08-17
CA1331611C (en) 1994-08-23
DK347289D0 (da) 1989-07-13
FI893408A0 (fi) 1989-07-13
NZ229929A (en) 1992-02-25
ZA895345B (en) 1991-03-27
EP0351215B1 (en) 1996-06-19
DE68926697D1 (de) 1996-07-25
FI91155C (fi) 1994-05-25
DE68926697T2 (de) 1996-12-12
US5079252A (en) 1992-01-07
IE892261L (en) 1990-01-14
EP0351215A2 (en) 1990-01-17
JP2791116B2 (ja) 1998-08-27
FI893408A (fi) 1990-01-15
KR900001697A (ko) 1990-02-27
IL90959A0 (en) 1990-02-09
IL90959A (en) 1994-02-27
ATE139535T1 (de) 1996-07-15
EP0351215A3 (en) 1991-08-14
MY104124A (en) 1993-12-31
PT91153B (pt) 1995-01-31
HUT50821A (en) 1990-03-28
PT91153A (pt) 1990-02-08
AU622686B2 (en) 1992-04-16
DK347289A (da) 1990-01-15
JPH0273086A (ja) 1990-03-13
HU210425B (en) 1995-04-28
AU3809789A (en) 1990-01-18
PH26913A (en) 1992-12-03

Similar Documents

Publication Publication Date Title
FI862011A0 (fi) Terapeutiska nukleosider.
ATE190064T1 (de) Kombination therapeutische nukleoside mit weiteren therapeutisch wirksamen komponenten.
PT87542A (pt) Process for the preparation of a medicament based on indolone derivatives for the treatment of the parkinson disease
NO172543C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte purinarabinosider
ATE82294T1 (de) Therapeutische nukleoside.
FI91155B (fi) Menetelmä uuden, terapeuttisesti käyttökelpoisen 9-(2-hydroksietoksimetyyli)guaniiniesterin valmistamiseksi
ATE63747T1 (de) Antivirale verbindungen.
ES467943A1 (es) Un metodo de preparacion de una purina sustituida.

Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: THE WELLCOME FOUNDATION LIMITED