FI903835A0 - Foerfarande foer framstaellning av farmaceutiskt anvaendbara 4-(n-substituerad amino)-2-butynyl-1 -tiourea och deras derivat. - Google Patents
Foerfarande foer framstaellning av farmaceutiskt anvaendbara 4-(n-substituerad amino)-2-butynyl-1 -tiourea och deras derivat.Info
- Publication number
- FI903835A0 FI903835A0 FI903835A FI903835A FI903835A0 FI 903835 A0 FI903835 A0 FI 903835A0 FI 903835 A FI903835 A FI 903835A FI 903835 A FI903835 A FI 903835A FI 903835 A0 FI903835 A0 FI 903835A0
- Authority
- FI
- Finland
- Prior art keywords
- butynyl
- preparation
- amino
- substituerad
- anvaendbara
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/02—Thiourea
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/388,785 US4988688A (en) | 1989-08-02 | 1989-08-02 | 4-(N-substituted amino)-2-butynyl-1-ureas and thioureas and derivatives thereof as centrally acting muscarinic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
FI903835A0 true FI903835A0 (fi) | 1990-08-01 |
Family
ID=23535507
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI903835A FI903835A0 (fi) | 1989-08-02 | 1990-08-01 | Foerfarande foer framstaellning av farmaceutiskt anvaendbara 4-(n-substituerad amino)-2-butynyl-1 -tiourea och deras derivat. |
Country Status (15)
Country | Link |
---|---|
US (1) | US4988688A (fi) |
EP (1) | EP0411615B1 (fi) |
JP (1) | JPH0374359A (fi) |
KR (1) | KR910004559A (fi) |
AT (1) | ATE99290T1 (fi) |
AU (1) | AU6001990A (fi) |
CA (1) | CA2022510A1 (fi) |
DE (1) | DE69005557T2 (fi) |
DK (1) | DK0411615T3 (fi) |
ES (1) | ES2062220T3 (fi) |
FI (1) | FI903835A0 (fi) |
IE (1) | IE902792A1 (fi) |
NO (1) | NO903384L (fi) |
PT (1) | PT94874A (fi) |
ZA (1) | ZA906057B (fi) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5202459A (en) * | 1989-11-07 | 1993-04-13 | Nippon Kayaku Kabushiki Kaisha | Process for producing cyclobutane derivative |
US5182284A (en) * | 1990-01-26 | 1993-01-26 | Taiho Pharmaceutical Co., Ltd. | Piperazine compounds, processes for preparation thereof and medical uses thereof |
FR2677019B1 (fr) * | 1991-05-27 | 1994-11-25 | Pf Medicament | Nouvelles piperidines disubstituees-1,4, leur preparation et leur application en therapeutique. |
AU7705694A (en) * | 1993-10-04 | 1995-05-01 | Glaxo Wellcome House | Substituted urea and isothiourea derivatives as no synthase inhibitors |
US6090846A (en) * | 1994-06-01 | 2000-07-18 | Glaxo Wellcome Inc. | Substituted urea and isothiourea derivatives as no synthase inhibitors |
US6225305B1 (en) | 1993-10-04 | 2001-05-01 | Glaxo Wellcome Inc. | Substituted urea and isothiorea derivatives as no synthase inhibitors |
US6297276B1 (en) | 1993-10-04 | 2001-10-02 | Glaxosmithkline | Substituted urea and isothiourea derivatives as no synthase inhibitors |
GB9418912D0 (en) * | 1994-09-20 | 1994-11-09 | Fisons Corp | Pharmaceutically active compounds |
TW397812B (en) * | 1995-02-11 | 2000-07-11 | Astra Ab | Bicyclic isothiourea derivatives useful in therapy |
US6545182B2 (en) * | 2000-04-13 | 2003-04-08 | Allergan Sales, Inc. | Methods and compositions for modulating alpha adrenergic receptor activity |
US6313172B1 (en) * | 2000-04-13 | 2001-11-06 | Allergan Sales, Inc. | Methods and compositions for modulating alpha adrenergic receptor activity |
US7185522B2 (en) | 2005-05-10 | 2007-03-06 | T. Sendzimir, Inc. | Side supported 6-high rolling mill |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4065471A (en) * | 1965-04-09 | 1977-12-27 | Sterling Drug Inc. | N-(4-Amino-2-butynyl)imides |
US3354178A (en) * | 1965-04-09 | 1967-11-21 | Sterling Drug Inc | Nu-(4-amino-2-butynyl)-nu-alkylcarboxamides |
-
1989
- 1989-08-02 US US07/388,785 patent/US4988688A/en not_active Expired - Fee Related
-
1990
- 1990-07-31 AU AU60019/90A patent/AU6001990A/en not_active Abandoned
- 1990-08-01 CA CA002022510A patent/CA2022510A1/en not_active Abandoned
- 1990-08-01 ES ES90114787T patent/ES2062220T3/es not_active Expired - Lifetime
- 1990-08-01 IE IE279290A patent/IE902792A1/en unknown
- 1990-08-01 AT AT90114787T patent/ATE99290T1/de not_active IP Right Cessation
- 1990-08-01 PT PT94874A patent/PT94874A/pt not_active Application Discontinuation
- 1990-08-01 DE DE90114787T patent/DE69005557T2/de not_active Expired - Fee Related
- 1990-08-01 FI FI903835A patent/FI903835A0/fi not_active Application Discontinuation
- 1990-08-01 JP JP2202622A patent/JPH0374359A/ja active Pending
- 1990-08-01 KR KR1019900011931A patent/KR910004559A/ko not_active Application Discontinuation
- 1990-08-01 ZA ZA906057A patent/ZA906057B/xx unknown
- 1990-08-01 NO NO90903384A patent/NO903384L/no unknown
- 1990-08-01 EP EP90114787A patent/EP0411615B1/en not_active Expired - Lifetime
- 1990-08-01 DK DK90114787.6T patent/DK0411615T3/da active
Also Published As
Publication number | Publication date |
---|---|
PT94874A (pt) | 1991-04-18 |
ATE99290T1 (de) | 1994-01-15 |
DE69005557D1 (de) | 1994-02-10 |
KR910004559A (ko) | 1991-03-28 |
AU6001990A (en) | 1991-02-07 |
ES2062220T3 (es) | 1994-12-16 |
EP0411615A1 (en) | 1991-02-06 |
NO903384D0 (no) | 1990-08-01 |
EP0411615B1 (en) | 1993-12-29 |
DE69005557T2 (de) | 1994-04-21 |
NO903384L (no) | 1991-02-04 |
DK0411615T3 (da) | 1994-01-24 |
ZA906057B (en) | 1992-04-29 |
US4988688A (en) | 1991-01-29 |
JPH0374359A (ja) | 1991-03-28 |
CA2022510A1 (en) | 1991-02-03 |
IE902792A1 (en) | 1991-02-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed |
Owner name: WARNER-LAMBERT COMPANY |