FI902422A0 - RENIN INHIBERANDE PEPTIDER SOM INNEHAOLLER AMINO- OCH HYDROXIDKARBOXYLSYROR. - Google Patents
RENIN INHIBERANDE PEPTIDER SOM INNEHAOLLER AMINO- OCH HYDROXIDKARBOXYLSYROR.Info
- Publication number
- FI902422A0 FI902422A0 FI902422A FI902422A FI902422A0 FI 902422 A0 FI902422 A0 FI 902422A0 FI 902422 A FI902422 A FI 902422A FI 902422 A FI902422 A FI 902422A FI 902422 A0 FI902422 A0 FI 902422A0
- Authority
- FI
- Finland
- Prior art keywords
- inhiberande
- hydroxidkarboxylsyror
- peptider
- renin
- och
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Crystallography & Structural Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12127087A | 1987-11-16 | 1987-11-16 | |
PCT/US1988/003436 WO1989004833A1 (en) | 1987-11-16 | 1988-10-11 | Renin inhibiting peptides that contain amino and hydroxy dicarboxylic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
FI902422A0 true FI902422A0 (en) | 1990-05-15 |
Family
ID=22395600
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI902422A FI902422A0 (en) | 1987-11-16 | 1990-05-15 | RENIN INHIBERANDE PEPTIDER SOM INNEHAOLLER AMINO- OCH HYDROXIDKARBOXYLSYROR. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0394311A1 (en) |
JP (1) | JPH03500886A (en) |
DK (1) | DK119590D0 (en) |
FI (1) | FI902422A0 (en) |
WO (1) | WO1989004833A1 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3941235A1 (en) * | 1989-12-14 | 1991-06-20 | Bayer Ag | NEW PEPTIDES, THEIR PREPARATION AND THEIR USE IN MEDICINAL PRODUCTS |
CA2191924A1 (en) * | 1995-12-05 | 1997-06-06 | Kevin Felsenstein | 5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives as inhibitors of .beta.-amyloid protein production |
US5703129A (en) * | 1996-09-30 | 1997-12-30 | Bristol-Myers Squibb Company | 5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives as inhibitors of β-amyloid protein production |
US6486193B2 (en) | 1998-12-31 | 2002-11-26 | Aventis Pharmaceuticals Inc. | 3-substituted pyrrolidines useful as inhibitors of matrix metalloproteinases |
US7205336B2 (en) | 2002-05-17 | 2007-04-17 | Merck & Co., Inc. | β-secretase inhibitors |
AU2004204692B2 (en) | 2003-01-07 | 2009-07-09 | Merck & Co., Inc. | Macrocyclic beta-secretase inhibitors for treatment of Alzheimer's disease |
CA2529994A1 (en) | 2003-06-30 | 2005-01-20 | Merck & Co., Inc. | N-alkyl phenylcarboxamide beta-secretase inhibitors for the treatment of alzheimer's disease |
AU2004255191A1 (en) | 2003-07-01 | 2005-01-20 | Merck & Co., Inc. | Phenylcarboxylate beta-secretase inhibitors for the treatment of Alzheimer's disease |
CN1859904A (en) | 2003-10-03 | 2006-11-08 | 默克公司 | Benzylether and benzylamino beta-secretase inhibitors for the treatment of alzheimer's disease |
CN116096714A (en) | 2020-06-10 | 2023-05-09 | 安力高医药股份有限公司 | Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections |
CA3224494A1 (en) | 2021-07-09 | 2023-01-12 | Koen Vandyck | Anti-viral compounds |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0209848A3 (en) * | 1985-07-24 | 1988-07-27 | Merck & Co. Inc. | Enzyme inhibitors |
DE3601248A1 (en) * | 1986-01-17 | 1987-07-23 | Hoechst Ag | SUBSTITUTED 4-AMINO-3-HYDROXYBUTTERIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THESE AGENTS AND THEIR USE |
DE3610593A1 (en) * | 1986-03-29 | 1987-10-01 | Hoechst Ag | SUBSTITUTED 4-AMINO-3-HYDROXYBUTTERIC ACID DERIVATIVES METHOD FOR THE PRODUCTION THEREOF, THE CONTAINERS THEREOF AND THEIR USE |
AU595309B2 (en) * | 1986-05-09 | 1990-03-29 | Dainippon Pharmaceutical Co. Ltd. | Tripeptide derivatives |
-
1988
- 1988-10-11 WO PCT/US1988/003436 patent/WO1989004833A1/en not_active Application Discontinuation
- 1988-10-11 EP EP89900393A patent/EP0394311A1/en not_active Withdrawn
- 1988-10-11 JP JP1500117A patent/JPH03500886A/en active Pending
-
1990
- 1990-05-14 DK DK119590A patent/DK119590D0/en not_active Application Discontinuation
- 1990-05-15 FI FI902422A patent/FI902422A0/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK119590A (en) | 1990-05-14 |
WO1989004833A1 (en) | 1989-06-01 |
DK119590D0 (en) | 1990-05-14 |
EP0394311A1 (en) | 1990-10-31 |
AU2806789A (en) | 1989-06-14 |
JPH03500886A (en) | 1991-02-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI884063A0 (en) | HYDROKRACKNINGSKATALYSATORER OCH -FOERFARANDEN SOM ANVAENDER ICKE-ZEOLITISKA MOLEKYLSAOLL. | |
FI884924A0 (en) | HUMANIMMUGLOBULIN SOM PRODUCERATS MED HYBRID-DNA-TEKNIK. | |
FI893334A (en) | TRYCKSENSITIVA BINDEMEDEL SOM INNEHAOLLER EN ALKOXIFUNKTIONELL KISELFOERENING. | |
FI896138A0 (en) | POLYOLPOLYESTRAR SOM FUKTIGHETSBARRIAER FOER LIVSMEDEL. | |
FI901256A0 (en) | FORMULATIONER SOM ADMINISTRERAS GENOM SLEMHINNA. | |
FI861396A0 (en) | BRAEDPARKETT SOM ISOLERAR STEGLJUDET. | |
FI902042A0 (en) | BENCEMENT SOM INNEHAOLLER CELLTILLVAEXTSTIMULANS. | |
FI870569A0 (en) | ANORDNING FOER TAETNING AV EN KAMMARE SOM INNEHAOLLER TRYCKMEDIUM. | |
FI884681A0 (en) | POLYAMIDBASFOERENINGAR SOM GJORTS ELDFASTA. | |
FI884721A (en) | ANVAENDNING AV FLUORDERIVAT SOM KONTRASTMEDEL. | |
FI902422A0 (en) | RENIN INHIBERANDE PEPTIDER SOM INNEHAOLLER AMINO- OCH HYDROXIDKARBOXYLSYROR. | |
FI890699A (en) | RENIN INHIBERANDE AMINOSYRADERIVAT. | |
FI893189A0 (en) | TETRAHALOFTALATESTRAR SOM BRANDSKYDDSVAETSKOR FOER VISSA HARTSER. | |
FI882643A0 (en) | FOERFARANDE FOER FRAMSTAELLNING AV EN SILAN- ELLER SILOXANFOERENING SOM INNEHAOLLER MINST EN CYKLOALKYLRING. | |
FI890033A0 (en) | BILDSKAERMANORDNING SOM INNEHAOLLER EN VAOGFORMSGENERATOR. | |
FI890147A0 (en) | AEMNEN SOM MOTVERKAR RYTMSTOERNINGAR. | |
FI884926A0 (en) | KOPOLYMERBESTRYKNINGSKOMPOSITIONER SOM INNEHAOLLER SULFOALKYLMONOMEREMULSIONSMEDEL. | |
FI874396A0 (en) | SKYDDSARRANGEMANG FOER OBJEKT SOM SKALL SKYDDAS. | |
FI874286A0 (en) | BAKSLADD SOM UPPVISAR EN VRIDBAR BETTSKIVA. | |
FI871457A (en) | TAETNINGSKONSTRUKTION FOER VENTILATIONSKANALER SOM SKALL ANSLUTAS TILL VARANDRA. | |
FI893925A (en) | AKRYLLIMKOMPOSITION SOM GER EN HAERDAD LIMFOG. | |
FI874737A0 (en) | BILDAECKDUBBNING SOM MINSKAR SLITAGEN AV VAEGBELAEGGNING. | |
FI870704A0 (en) | SLIRSKYDD SOM FOERHINDRAR SKIDAN ATT GLIDA BAKAOT. | |
FI875421A0 (en) | FARTYG SOM AENDRAR SIN STAELLNING. | |
FI872716A0 (en) | SYSTEM SOM CENTRERAR SOLENS STRAOLNING. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed | ||
MM | Patent lapsed |
Owner name: THE UPJOHN COMPANY |