DK119590D0 - PURE INHIBIT PAPTIDES - Google Patents

PURE INHIBIT PAPTIDES

Info

Publication number
DK119590D0
DK119590D0 DK119590A DK119590A DK119590D0 DK 119590 D0 DK119590 D0 DK 119590D0 DK 119590 A DK119590 A DK 119590A DK 119590 A DK119590 A DK 119590A DK 119590 D0 DK119590 D0 DK 119590D0
Authority
DK
Denmark
Prior art keywords
paptides
inhibit
pure
pure inhibit
inhibit paptides
Prior art date
Application number
DK119590A
Other languages
Danish (da)
Other versions
DK119590A (en
Inventor
Suvit Thaisrivongs
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of DK119590A publication Critical patent/DK119590A/en
Publication of DK119590D0 publication Critical patent/DK119590D0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK119590A 1987-11-16 1990-05-14 PURE INHIBIT PAPTIDES DK119590D0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12127087A 1987-11-16 1987-11-16
PCT/US1988/003436 WO1989004833A1 (en) 1987-11-16 1988-10-11 Renin inhibiting peptides that contain amino and hydroxy dicarboxylic acids

Publications (2)

Publication Number Publication Date
DK119590A DK119590A (en) 1990-05-14
DK119590D0 true DK119590D0 (en) 1990-05-14

Family

ID=22395600

Family Applications (1)

Application Number Title Priority Date Filing Date
DK119590A DK119590D0 (en) 1987-11-16 1990-05-14 PURE INHIBIT PAPTIDES

Country Status (5)

Country Link
EP (1) EP0394311A1 (en)
JP (1) JPH03500886A (en)
DK (1) DK119590D0 (en)
FI (1) FI902422A0 (en)
WO (1) WO1989004833A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3941235A1 (en) * 1989-12-14 1991-06-20 Bayer Ag NEW PEPTIDES, THEIR PREPARATION AND THEIR USE IN MEDICINAL PRODUCTS
CA2191924A1 (en) * 1995-12-05 1997-06-06 Kevin Felsenstein 5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives as inhibitors of .beta.-amyloid protein production
US5703129A (en) * 1996-09-30 1997-12-30 Bristol-Myers Squibb Company 5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives as inhibitors of β-amyloid protein production
US6486193B2 (en) 1998-12-31 2002-11-26 Aventis Pharmaceuticals Inc. 3-substituted pyrrolidines useful as inhibitors of matrix metalloproteinases
US7205336B2 (en) 2002-05-17 2007-04-17 Merck & Co., Inc. β-secretase inhibitors
CA2512111A1 (en) 2003-01-07 2004-07-29 Merck And Co., Inc. Macrocyclic beta-secretase inhibitors for treatment of alzheimer's disease
CN100430377C (en) 2003-06-30 2008-11-05 麦克公司 N-alkyl phenylcarboxamide beta-secretase inhibitors for the treatment of alzheimer's disease
WO2005004803A2 (en) 2003-07-01 2005-01-20 Merck & Co., Inc. Phenylcarboxylate beta-secretase inhibitors for the treatment of alzheimer's disease
JP4649413B2 (en) 2003-10-03 2011-03-09 メルク・シャープ・エンド・ドーム・コーポレイション Benzyl ether and benzylamino β-secretase inhibitors for the treatment of Alzheimer's disease
EP4165037A4 (en) 2020-06-10 2024-07-03 Aligos Therapeutics Inc Anti-viral compounds for treating coronavirus, picornavirus, and norovirus infections
IL309732A (en) 2021-07-09 2024-02-01 Aligos Therapeutics Inc Anti-viral compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0209848A3 (en) * 1985-07-24 1988-07-27 Merck & Co. Inc. Enzyme inhibitors
DE3601248A1 (en) * 1986-01-17 1987-07-23 Hoechst Ag SUBSTITUTED 4-AMINO-3-HYDROXYBUTTERIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THESE AGENTS AND THEIR USE
DE3610593A1 (en) * 1986-03-29 1987-10-01 Hoechst Ag SUBSTITUTED 4-AMINO-3-HYDROXYBUTTERIC ACID DERIVATIVES METHOD FOR THE PRODUCTION THEREOF, THE CONTAINERS THEREOF AND THEIR USE
AU595309B2 (en) * 1986-05-09 1990-03-29 Dainippon Pharmaceutical Co. Ltd. Tripeptide derivatives

Also Published As

Publication number Publication date
WO1989004833A1 (en) 1989-06-01
FI902422A0 (en) 1990-05-15
JPH03500886A (en) 1991-02-28
EP0394311A1 (en) 1990-10-31
DK119590A (en) 1990-05-14
AU2806789A (en) 1989-06-14

Similar Documents

Publication Publication Date Title
ATA30988A (en) ALPINSKI
DK580888A (en) combine
ATA174488A (en) ALPINSKI
ATA174288A (en) ALPINSKI
ATA224788A (en) CALCITON INSUPPOSITORIES
DK119590A (en) PURE INHIBIT PAPTIDES
BR8705012A (en) MINI-PERSIANA
AT389045B (en) PARAOCCLUSAL LOEFFEL
ATA48687A (en) GUELLEFASS
ATA294988A (en) HAECKSLER
AT388649B (en) SPORTSHOE
ATA162787A (en) HOERGERAET
IT8744204A0 (en) THINNER
ES1002105Y (en) CASE
ES1003151Y (en) PORTALENTILLAS CASE
BR6700502U (en) CASE
BR6700503U (en) CASE
BR8705845A (en) HYDROCAPACITOR
BR8704776A (en) MULTIALARME
BR6701723U (en) LEVEL-ATMOSPHERE-PROFESSIONAL
BR6701734U (en) AMNIOSCOPIO
ATA257287A (en) GLYCOPEPTIDANTIBIOTICS
BR6702354U (en) STAIRS-HANGER
BR6702835U (en) LIFEBOARD
BR8700074A (en) DIAGRAMMER

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment