FI896001A0 - Kloning och expression av transformationstillvaextfaktorn b2. - Google Patents
Kloning och expression av transformationstillvaextfaktorn b2.Info
- Publication number
- FI896001A0 FI896001A0 FI896001A FI896001A FI896001A0 FI 896001 A0 FI896001 A0 FI 896001A0 FI 896001 A FI896001 A FI 896001A FI 896001 A FI896001 A FI 896001A FI 896001 A0 FI896001 A0 FI 896001A0
- Authority
- FI
- Finland
- Prior art keywords
- transformationstillvaextfaktorn
- kloning
- och
- expression
- och expression
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28514088A | 1988-12-16 | 1988-12-16 | |
US07/446,020 US5221620A (en) | 1987-10-06 | 1989-12-05 | Cloning and expression of transforming growth factor β2 |
Publications (1)
Publication Number | Publication Date |
---|---|
FI896001A0 true FI896001A0 (fi) | 1989-12-14 |
Family
ID=26963007
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI896001A FI896001A0 (fi) | 1988-12-16 | 1989-12-14 | Kloning och expression av transformationstillvaextfaktorn b2. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5221620A (fi) |
EP (2) | EP0676474A1 (fi) |
CN (1) | CN1045992A (fi) |
AU (1) | AU640115B2 (fi) |
DK (1) | DK638389A (fi) |
FI (1) | FI896001A0 (fi) |
IL (1) | IL92737A0 (fi) |
NZ (1) | NZ231803A (fi) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0502036T3 (da) * | 1989-11-22 | 1996-05-06 | Genentech Inc | Latens-associeret peptid og anvendelser herfor |
US5168050A (en) * | 1990-05-24 | 1992-12-01 | Genentech, Inc. | Mammalian expression of the bone morphogenetic protein-2b using bmp2a/bmp2b fusion |
US5206023A (en) * | 1991-01-31 | 1993-04-27 | Robert F. Shaw | Method and compositions for the treatment and repair of defects or lesions in cartilage |
US5270300A (en) * | 1991-09-06 | 1993-12-14 | Robert Francis Shaw | Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone |
US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
AU2738392A (en) * | 1991-11-11 | 1993-05-13 | Ciba-Geigy Ag | Novel hybrid transforming growth factors |
IT1259042B (it) * | 1992-01-27 | 1996-03-11 | Mini Ricerca Scient Tecnolog | Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante |
JP3193050B2 (ja) * | 1992-02-12 | 2001-07-30 | ビオファルム ゲゼルシャフト ツア ビオテヒノロ ギッシェン エントヴィックルング フォン ファル マカ ミット ベシュレンクテル ハフツング | 新規の増殖/分化因子をコード化するdna配列 |
US5847007A (en) * | 1993-05-13 | 1998-12-08 | Neorx Corporation | Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells |
US6306421B1 (en) | 1992-09-25 | 2001-10-23 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5770609A (en) * | 1993-01-28 | 1998-06-23 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6395494B1 (en) * | 1993-05-13 | 2002-05-28 | Neorx Corporation | Method to determine TGF-β |
US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5595722A (en) * | 1993-01-28 | 1997-01-21 | Neorx Corporation | Method for identifying an agent which increases TGF-beta levels |
US6663881B2 (en) | 1993-01-28 | 2003-12-16 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5981568A (en) * | 1993-01-28 | 1999-11-09 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
WO1994025588A2 (en) * | 1993-04-30 | 1994-11-10 | Biognostik Gesellschaft für Biomolekulare Diagnostik mbH | ANTISENSE-OLIGONUCLEOTIDES FOR THE TREATMENT OF IMMUNOSUPPRESSIVE EFFECTS OF TRANSFORMING GROWTH FACTOR-β (TGF-β) |
US6521227B1 (en) | 1999-11-18 | 2003-02-18 | Peter L. Hudson | Polynucleotides encoding prostatic growth factor and process for producing prostatic growth factor polypeptides |
US5994102A (en) * | 1994-12-15 | 1999-11-30 | Human Genome Sciences, Inc. | Polynucleotides encoding prostatic growth factor and process for producing prostatic growth factor polypeptides |
AU6277396A (en) | 1995-06-07 | 1996-12-30 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies with tamoxifen analogues |
EP0856579A1 (en) * | 1997-01-31 | 1998-08-05 | BIOGNOSTIK GESELLSCHAFT FÜR BIOMOLEKULARE DIAGNOSTIK mbH | An antisense oligonucleotide preparation method |
AU6959898A (en) | 1997-04-11 | 1998-11-11 | David J. Grainger | Compounds and therapies for the prevention of vascular and non-vascular pathol ogies |
EP1117805A2 (en) * | 1998-10-07 | 2001-07-25 | STRYKER CORPORATION (a Michigan corporation) | Modified tgf-beta superfamily proteins |
US6756215B1 (en) * | 2000-10-20 | 2004-06-29 | The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services | Functionalized TGF-β fusion proteins |
EP1740609A2 (en) | 2004-04-27 | 2007-01-10 | Research Development Foundation | Antagonism of tgf-beta superfamily receptor signaling |
CN100389120C (zh) * | 2005-04-12 | 2008-05-21 | 中国人民解放军第三军医大学野战外科研究所 | 封闭TGF-β1的反义寡核苷酸及其在制备治疗纤维化相关疾病药物中的用途 |
US20110002897A1 (en) | 2009-06-11 | 2011-01-06 | Burnham Institute For Medical Research | Directed differentiation of stem cells |
US9758786B2 (en) | 2016-02-09 | 2017-09-12 | Autotelic, Llc | Compositions and methods for treating pancreatic cancer |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4399216A (en) * | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
US4338397A (en) * | 1980-04-11 | 1982-07-06 | President And Fellows Of Harvard College | Mature protein synthesis |
US4546082A (en) * | 1982-06-17 | 1985-10-08 | Regents Of The Univ. Of California | E. coli/Saccharomyces cerevisiae plasmid cloning vector containing the alpha-factor gene for secretion and processing of hybrid proteins |
EP0105014B1 (en) * | 1982-09-24 | 1992-05-20 | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce | Repair of tissue in animals |
CA1230591A (en) * | 1983-06-03 | 1987-12-22 | Charles A. Frolik | PURIFIED TRANSFORMING GROWTH FACTOR-.beta. DERIVED FROM HUMAN PLATELETS AND PLACENTAS |
CA1341401C (en) * | 1984-03-23 | 2002-11-26 | Adriano Fontana | Immunosuppressant factor derived from human glioblastoma cells |
EP0155433A1 (en) * | 1984-03-23 | 1985-09-25 | Adriano Fontana | Immunosuppressant factor |
US4708948A (en) * | 1984-04-20 | 1987-11-24 | The United States Of America As Represented By The Department Of Health And Human Services | Substantially purified tumor growth inhibitory factor |
EP0169016B2 (en) * | 1984-07-16 | 2004-04-28 | Celtrix Pharmaceuticals, Inc. | Polypeptide cartilage-inducing factors found in bone |
IL78197A (en) * | 1985-03-22 | 1991-07-18 | Genentech Inc | Nucleic acid encoding tgf-beta and its uses |
KR890700031A (ko) * | 1986-11-17 | 1989-03-02 | 예안 크라메르 한스 루돌프 하우스 | 신규한 t-세포 억압 인자의 제조 및 그것의 용도 |
AU1539188A (en) * | 1987-05-04 | 1988-11-10 | Bristol-Myers Squibb Company | TGF-B2 and novel compositions having anti-neoplastic activity |
AU626524B2 (en) * | 1987-05-29 | 1992-08-06 | Bristol-Myers Squibb Company | Cloning and expression of simian transforming growth factor- beta 1 |
AU630075B2 (en) * | 1987-10-06 | 1992-10-22 | Bristol-Myers Squibb Company | Cloning and expression of transforming growth factor 2b |
IL87877A0 (en) * | 1987-10-06 | 1989-03-31 | Oncogen | Cloning and expression of transforming growth factor beta2 |
-
1989
- 1989-12-05 US US07/446,020 patent/US5221620A/en not_active Expired - Fee Related
- 1989-12-14 EP EP95104223A patent/EP0676474A1/en not_active Withdrawn
- 1989-12-14 FI FI896001A patent/FI896001A0/fi not_active IP Right Cessation
- 1989-12-14 EP EP19890403480 patent/EP0376785A3/en not_active Ceased
- 1989-12-15 NZ NZ231803A patent/NZ231803A/xx unknown
- 1989-12-15 DK DK638389A patent/DK638389A/da not_active Application Discontinuation
- 1989-12-15 AU AU46835/89A patent/AU640115B2/en not_active Ceased
- 1989-12-15 IL IL92737A patent/IL92737A0/xx unknown
- 1989-12-16 CN CN89109814.3A patent/CN1045992A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
IL92737A0 (en) | 1990-09-17 |
DK638389A (da) | 1990-06-17 |
NZ231803A (en) | 1992-10-28 |
AU640115B2 (en) | 1993-08-19 |
EP0676474A1 (en) | 1995-10-11 |
DK638389D0 (da) | 1989-12-15 |
US5221620A (en) | 1993-06-22 |
EP0376785A3 (en) | 1992-01-02 |
CN1045992A (zh) | 1990-10-10 |
AU4683589A (en) | 1991-06-21 |
EP0376785A2 (en) | 1990-07-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed | ||
MM | Patent lapsed |
Owner name: ONCOGEN LIMITED PARTNERSHIP |