FI894487A - Anvaendning av 2,7-diamino-1,2,3,4 -tetrahydronaftaliner som laekemedel, nya 2,7-diamino-1,2,3,4 -tetrahydronaftaliner samt foerfarande foer deras framstaellning. - Google Patents

Anvaendning av 2,7-diamino-1,2,3,4 -tetrahydronaftaliner som laekemedel, nya 2,7-diamino-1,2,3,4 -tetrahydronaftaliner samt foerfarande foer deras framstaellning. Download PDF

Info

Publication number
FI894487A
FI894487A FI894487A FI894487A FI894487A FI 894487 A FI894487 A FI 894487A FI 894487 A FI894487 A FI 894487A FI 894487 A FI894487 A FI 894487A FI 894487 A FI894487 A FI 894487A
Authority
FI
Finland
Prior art keywords
tetrahydronaftaliner
diamino
anvaendning
nya
foerfarande foer
Prior art date
Application number
FI894487A
Other languages
English (en)
Other versions
FI894487A0 (fi
Inventor
Matthias Grauert
Herbert Merz
Joachim Mierau
Guenter Schingnitz
Claus Schneider
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of FI894487A0 publication Critical patent/FI894487A0/fi
Publication of FI894487A publication Critical patent/FI894487A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C07C271/30—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a six-membered aromatic ring being part of a condensed ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/57—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems of the carbon skeleton
    • C07C211/60—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems of the carbon skeleton containing a ring other than a six-membered aromatic ring forming part of at least one of the condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/24—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
FI894487A 1988-09-24 1989-09-22 Anvaendning av 2,7-diamino-1,2,3,4 -tetrahydronaftaliner som laekemedel, nya 2,7-diamino-1,2,3,4 -tetrahydronaftaliner samt foerfarande foer deras framstaellning. FI894487A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3832571A DE3832571A1 (de) 1988-09-24 1988-09-24 Verwendung von 2,7-diamino-1,2,3,4-tetrahydronaphthalinen als arzneimittel, neue 2,7-diamino-1,2,3,4-tetrahydronaphthaline sowie verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
FI894487A0 FI894487A0 (fi) 1989-09-22
FI894487A true FI894487A (fi) 1990-03-25

Family

ID=6363689

Family Applications (1)

Application Number Title Priority Date Filing Date
FI894487A FI894487A (fi) 1988-09-24 1989-09-22 Anvaendning av 2,7-diamino-1,2,3,4 -tetrahydronaftaliner som laekemedel, nya 2,7-diamino-1,2,3,4 -tetrahydronaftaliner samt foerfarande foer deras framstaellning.

Country Status (15)

Country Link
US (1) US5053430A (fi)
EP (1) EP0361300A1 (fi)
JP (1) JPH02180857A (fi)
KR (1) KR900004673A (fi)
AU (1) AU626906B2 (fi)
DD (1) DD290136A5 (fi)
DE (1) DE3832571A1 (fi)
DK (1) DK467789A (fi)
FI (1) FI894487A (fi)
HU (1) HUT58038A (fi)
IL (1) IL91737A0 (fi)
NO (1) NO893768L (fi)
NZ (1) NZ230754A (fi)
PT (1) PT91767A (fi)
ZA (1) ZA897228B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3837809A1 (de) * 1988-11-08 1990-05-10 Merck Patent Gmbh Tetralinderivate
GB9019942D0 (en) * 1990-09-12 1990-10-24 Wyeth John & Brother Ltd Azetidine derivatives
US6197798B1 (en) 1998-07-21 2001-03-06 Novartis Ag Amino-benzocycloalkane derivatives
PT1259484E (pt) * 2000-01-18 2005-09-30 Novartis Ag Carboxamidas uteis como inibidores de proteina de transferencia de triglicerido microsomal e de secrecao de apolipoproteina b
EP2507204B1 (de) 2009-12-04 2014-08-06 Basf Se Verfahren zur herstellung von aromatischen formamiden

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat
US4320148A (en) * 1980-11-24 1982-03-16 Smithkline Corporation 2-Aminotetralin compounds, pharmaceutical compositions and method of producing central alpha1 agonist activity
US4370341A (en) * 1980-12-11 1983-01-25 Ayerst, Mckenna & Harrison, Ltd. 6,7,8,9-Tetrahydro-3H-benz[E]indol-8-amine derivatives
CA1159459A (en) * 1980-12-11 1983-12-27 Andre A. Asselin 6,7,8,9-tetrahydro-3h-benz¬e| indolamine derivatives
FR2512814A1 (fr) * 1981-09-16 1983-03-18 Synthelabo Derives d'amino-2 tetrahydro-1,2,3,4 naphtalene, leur preparation et leur application en therapeutique
US4520030A (en) * 1983-12-12 1985-05-28 Synthelabo Anti-ulcer agents
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline

Also Published As

Publication number Publication date
DD290136A5 (de) 1991-05-23
PT91767A (pt) 1990-03-30
NO893768D0 (no) 1989-09-22
HUT58038A (en) 1992-01-28
DK467789A (da) 1990-03-25
DE3832571A1 (de) 1990-05-31
AU626906B2 (en) 1992-08-13
NO893768L (no) 1990-03-26
KR900004673A (ko) 1990-04-12
EP0361300A1 (de) 1990-04-04
JPH02180857A (ja) 1990-07-13
AU4163289A (en) 1990-03-29
DK467789D0 (da) 1989-09-22
NZ230754A (en) 1992-02-25
FI894487A0 (fi) 1989-09-22
IL91737A0 (en) 1990-06-10
US5053430A (en) 1991-10-01
ZA897228B (en) 1991-06-26

Similar Documents

Publication Publication Date Title
FI901956A0 (fi) Nya naftalenylalkyl-3h-1,2,3,5 -oxatiadiazol-2-oxider anvaendbara som antihyperglykemiska medel.
FI894629A0 (fi) Nya 3,4-diaminokinolin- och -pyridinfoereningar.
FI901928A0 (fi) Foerfarande foer behandling av papper eller kartong foer att hoeja tjockleken av vattenaongar eller aromtjockleken samt papper eller kartong som behandlats enligt detta foerfarande.
FI911606A0 (fi) Foerfarande foer framstaellning av nya foereningar, som inhiberar trombocytaggregation.
FI913317A0 (fi) Foerfarande foer framstaellning av trae-plast-agglomerat, samt anvaendning daerav.
FI881613A (fi) Nya 2-acylpyrrolidinderivat, foerfarande foer framstaellning av dem, laekemedel innehaollande dessa samt deras anvaendning.
FI875397A0 (fi) Substituerade aminometyl-5,6,7,8 -tetrahydronaftyl-oxiaettikasyror, nya mellanprodukter, foerfarande foer deras framstaellning samt deras anvaendning i laekemedel.
FI904191A0 (fi) Nya aminopropanolderivater, foerfarande foer tillverkning av dessa samt farmaceutiska sammansaettningar som innehaoller dessa.
FI895800A0 (fi) Foerfarande foer framstaellning av nya a-cyano-b-oxopropionamider.
FI894487A0 (fi) Anvaendning av 2,7-diamino-1,2,3,4 -tetrahydronaftaliner som laekemedel, nya 2,7-diamino-1,2,3,4 -tetrahydronaftaliner samt foerfarande foer deras framstaellning.
FI890903A0 (fi) Nya trisubstituerade aminer, foerfarande foer framstaellning av dessa samt laekemedel innehaollande dessa foereningar.
FI881899A0 (fi) Nya 2 ,16 -diaminoandrostaner.
FI864716A0 (fi) Nya kefalosporiner, deras framstaellningsfoerfarande samt deras anvaendning som laekemedel.
FI893863A0 (fi) Foerfarande foer neutralisering av svavelsyra som innehaoller zinkjoner.
FI875787A0 (fi) Foerfarande foer framstaellning av lipofila aminosyraderivat, samt lipofila aminosyraderivat.
FI900051A0 (fi) Nya l-fukos-analoger, foerfarande foer framstaellning daerav, anvaendningen av dessa analoger foer framstaellning av nya glykaler, antracykliner som erhaollits medelst dessa glykaler samt anvaendningen av sagda antracykliner som farmaceutiska produkter.
FI900661A0 (fi) Nya formbara sammansaettningar som haerdas i vaerme.
FI843226A0 (fi) Aminoalkylimidazotiadiazolylalken- karboxylsyraamider, nya mellanprodukter foer framstaellning av dessa framstaellning av dem samt deras anvaendning som laekemedel.
FI894475A0 (fi) Anvaendning av sampolymerisat innehaollande aminogrupper i vattenbaserade kompositioner som grundfaerg.
FI906330A (fi) Nya fenoxialkylkarboxylsyraamider, foerfaranden foer framstaellning av desamma samt laekemedel innehaollande av dessa foereningar.
FI893816A (fi) Foerfarande foer framstaellning av nya bensazolderivat.
FI893291A0 (fi) Foerfarande foer framstaellning av nya allylaminoetylazoler.
FI932034A0 (fi) Nya 1-azacykloalkanderivat, farmaceutiska sammansaettningar som innehaoller dessa samt foerfarande foer framstaellning daerav
FI901955A0 (fi) Nya naftalenyl-3h-1,2,3,5-oxatiadiazol -2-oxider anvaendbara som, antihyperglykemiska medel.
FI870596A (fi) Nya antibiotika av streptogramintyp, mikrobiologiskt foerfarande foer deras framstaellning samt deras anvaendning som laekemedel och fodertillsatsmedel.

Legal Events

Date Code Title Description
FD Application lapsed
MM Patent lapsed

Owner name: BOEHRINGER INGELHEIM KG