FI893211L - Antihypertensiva, n-terminala eteraminodiolamino-syraderivat. - Google Patents

Antihypertensiva, n-terminala eteraminodiolamino-syraderivat. Download PDF

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Publication number
FI893211L
FI893211L FI893211A FI893211A FI893211L FI 893211 L FI893211 L FI 893211L FI 893211 A FI893211 A FI 893211A FI 893211 A FI893211 A FI 893211A FI 893211 L FI893211 L FI 893211L
Authority
FI
Finland
Prior art keywords
etheraminodiolamino
antihypertensive
terminal
acid derivatives
derivatives
Prior art date
Application number
FI893211A
Other languages
English (en)
Finnish (fi)
Other versions
FI893211A7 (fi
FI893211A0 (fi
Inventor
Gunnar J Hanson
John S Baran
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/214,698 external-priority patent/US4900746A/en
Application filed by Searle & Co filed Critical Searle & Co
Publication of FI893211A0 publication Critical patent/FI893211A0/fi
Publication of FI893211A7 publication Critical patent/FI893211A7/fi
Publication of FI893211L publication Critical patent/FI893211L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/16Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/26Radicals substituted by carbon atoms having three bonds to hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI893211A 1988-07-01 1989-06-30 Antihypertensiva, n-terminala eteraminodiolamino-syraderivat. FI893211L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/214,698 US4900746A (en) 1988-07-01 1988-07-01 Ethereal N-terminal aminodiol amino acid derivatives as anti-hypertensive agents
US37096289A 1989-06-28 1989-06-28

Publications (3)

Publication Number Publication Date
FI893211A0 FI893211A0 (fi) 1989-06-30
FI893211A7 FI893211A7 (fi) 1990-01-02
FI893211L true FI893211L (fi) 1990-01-02

Family

ID=26909259

Family Applications (1)

Application Number Title Priority Date Filing Date
FI893211A FI893211L (fi) 1988-07-01 1989-06-30 Antihypertensiva, n-terminala eteraminodiolamino-syraderivat.

Country Status (9)

Country Link
EP (1) EP0349921A3 (de)
JP (1) JPH03505584A (de)
KR (1) KR900701737A (de)
AU (2) AU616282B2 (de)
FI (1) FI893211L (de)
IL (1) IL90822A0 (de)
NO (1) NO892727L (de)
NZ (1) NZ229791A (de)
WO (1) WO1990000051A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2010531A1 (en) * 1989-03-06 1990-09-06 Werner Neidhart Amino acid derivatives
WO1994007845A1 (en) * 1992-09-25 1994-04-14 Bio-Mega/Boehringer Ingelheim Research Inc. N-(hydroxyethyl)butanediamide derivatives as renin inhibitors

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59227851A (ja) * 1983-06-09 1984-12-21 Sankyo Co Ltd レニン阻害作用を有するペプチド類
US4652551A (en) * 1984-06-22 1987-03-24 Abbott Laboratories Renin inhibiting compounds
US4645759A (en) * 1984-06-22 1987-02-24 Abbott Laboratories Renin inhibiting compounds
EP0181110A3 (de) * 1984-10-22 1988-05-11 Kissei Pharmaceutical Co. Ltd. Histidinderivate als Renininhibitoren
DK34086A (da) * 1985-01-23 1986-07-24 Abbott Lab Peptidylaminodioler
JPS61236770A (ja) * 1985-04-15 1986-10-22 Kissei Pharmaceut Co Ltd 新規なアミノ酸誘導体
JPS6256458A (ja) * 1985-09-04 1987-03-12 Kissei Pharmaceut Co Ltd 新規なアミノ酸誘導体
NZ218937A (en) * 1986-01-16 1990-03-27 Abbott Lab Functionalised peptidyl aminodiols and -triols as renin inhibitors and pharmaceutical compositions
IL81234A (en) * 1986-01-16 1992-09-06 Abbott Lab Peptidylaminodiols,process for their preparation and pharmaceutical compositions comprising them
EP0258289A4 (en) * 1986-01-16 1991-01-02 Joseph Dellaria Peptide analogs
US5032577A (en) * 1986-12-31 1991-07-16 Abbott Laboratories Peptidylaminodiols
US4921855A (en) * 1987-06-22 1990-05-01 Fujisawa Pharmaceutical Co., Ltd. New Histidyl amino acid derivatives, and pharmaceutical composition comprising the same
IL87614A0 (en) * 1987-09-16 1989-01-31 Abbott Lab Peptidylheterocycles

Also Published As

Publication number Publication date
FI893211A7 (fi) 1990-01-02
KR900701737A (ko) 1990-12-04
FI893211A0 (fi) 1989-06-30
WO1990000051A1 (en) 1990-01-11
EP0349921A2 (de) 1990-01-10
NO892727D0 (no) 1989-06-30
AU616282B2 (en) 1991-10-24
IL90822A0 (en) 1990-01-18
NO892727L (no) 1990-01-02
AU3726089A (en) 1990-02-01
JPH03505584A (ja) 1991-12-05
NZ229791A (en) 1991-08-27
AU3870689A (en) 1990-01-23
EP0349921A3 (de) 1991-08-21

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Legal Events

Date Code Title Description
FD Application lapsed
FD Application lapsed

Owner name: G D SEARLE & CO.